Photoactivated chemotherapy (PACT), an oxygen-independent light-based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target-specific activation while minimizing off-target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that could improve cancer treatment.

This study investigates the potential of optical coherence tomography (OCT) combined with deep learning for the diagnosis and treatment evaluation of melasma. A portable OCT system was developed for imaging skin, with which a VGG16-based diagnostic model was built, yielding a good differentiation of melasma.

Experimental process to evaluate the optomechanical and structural properties of individual macroscopic layers in swine skin tissues treated with a nontoxic optical clearing agent.

This study presents a compact monocular VO that captures high-frame-rate retinal videos of the ONH during flicker light stimulation. The device demonstrated its ability to detect flicker-induced changes in retinal parameters related to blood flow in healthy subjects, providing insights into temporal and spatial retinal variations.

The setup of our experiment is shown on Labrador, Johny, a canine participant of our research. The schematic of the setup features: green laser, digital camera, source of smell, and computer. Regions of the brain that were tested are highlighted. Note that the hippocampus and amygdala are on both sides of the dog's brain.