Journal of Biophotonics, a Wiley physics journal, focuses on the interdisciplinary field of biophotonics, publishing cutting-edge research on interactions between light and biological material.

We cover photonics research in areas such as life sciences, medicine and biomedicine, environmental science, nutrition, biology, physics, and chemistry, ranging from fundamental research to the latest clinical applications.

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The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.

Transmission in near‐infrared optical windows for deep brain imaging

  •  38-43
  •  10 November 2015

Graphical Abstract


Near-infrared (NIR) radiation has been employed using one- and two-photon excitation of fluorescence imaging at wavelengths 650–950 nm for deep brain imaging. However, longer wavelengths in NIR have been overlooked due to a lack of suitable NIR-low band gap semiconductor imaging detectors and/or femtosecond laser sources. This research introduces three new optical windows in NIR and demonstrates their potential for deep brain tissue imaging.

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Mueller polarimetric imaging for surgical and diagnostic applications: a review

  •  950-982
  •  2 May 2017

Graphical Abstract

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Polarization is a fundamental property of light that is able to provide an interesting and unique insight into tissue. Tissue polarization properties convey morphological, micro-structural and compositional information of tissue with great potential for label free characterization of tissue pathological changes. Recent progress in tissue polarimetric imaging and polarization resolved endoscopy paved the way for translation of polarimetric imaging to surgery and tissue diagnosis.

Application of circularly polarized light for non‐invasive diagnosis of cancerous tissues and turbid tissue‐like scattering media

  •  317-323
  •  18 October 2014

Graphical Abstract


The directional awareness of circularly and elliptically polarized light backscattered from turbid tissue-like scattering media is exploited. Circularly and elliptically polarized laser light is applied which illuminates the tissue samples of interest. It is demonstrated that the Stokes vector of backscattered light depicted on a Poincaré sphere can be used for characterization of cancerous and non-cancerous tissue samples in vitro.

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