International Journal of Developmental Neuroscience publishes research spanning fundamental and clinical aspects of nervous system development, renewal, regeneration, and the impact of genetic and environmental factors on brain development and neurodevelopmental disorders. We encourage studies on stem cell involvement in nervous system health, neurodegenerative disease investigation, neuroinflammation, and neuroevolution. The journal serves as a valuable resource for biologists and physicians, supported by The International Society for Developmental Neuroscience.

Articles

RESEARCH ARTICLE

Oxidative stress and apoptosis of the spinal cord in a rat model of retinoic acid‐induced neural tube defects

Peng Wu, Nan Shen, Shaoguang Feng, Weiguang Liu, Jun Wang, Chen Wang, 
  •  5 December 2024

Graphical Abstract

Oxidative stress and apoptosis of the spinal cord in a rat model of retinoic acid-induced neural tube defects Issue ,

Our findings reveal heightened oxidative stress and elevated apoptosis in the spinal cord of embryos with NTDs, suggesting these factors contribute significantly to the pathophysiology of NTDs. This research enhances understanding of NTDs' molecular basis, offering potential avenues for intervention to mitigate these devastating conditions in human pregnancies.

RESEARCH ARTICLE

Ascorbic acid supplementation in adolescent rats ameliorates anxiety‐like and depressive‐like manifestations of nicotine‐ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms

Alireza Najafzadeh, Mobina Mahdizadeh, Samaneh Kakhki, Ali Rahimi, S. Mohammad Ahmadi-Soleimani, Farimah Beheshti, 
  •  4 December 2024

Graphical Abstract

Ascorbic acid supplementation in adolescent rats ameliorates anxiety-like and depressive-like manifestations of nicotine-ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms Issue ,

Adolescent male rats were divided 7 groups: 1) vehicle, 2) Nicotine (Nic)-Ethanol (Eth), 3-5) Nic-Eth-Vit C 100/200/400, 6) Nic-Eth-Bupropion (Bup)- Naloxone (Nal) and 7) Vit C 400mg/kg. Behavioral assessments were done by EPM, FST, MBT, and OFT. Furthermore, specific biochemical variables associated with oxidative, inflammatory, and serotonergic profiles were quantified.

REVIEW ARTICLE

The effect of early weaning on feeding behavior parameters in rodents: A systematic review

Swane Miranda Alves, Elifrances Galdino de Oliveira, Eulália Rebeca Da Silva Araújo, Paula Brielle Pontes Silva, Raul Manhães de Castro, Sandra Lopes de Souza, 
  •  3 December 2024

Graphical Abstract

The effect of early weaning on feeding behavior parameters in rodents: A systematic review Issue ,

Early weaning causes changes in eating behavior and metabolism that, if not reversed, can have negative health consequences.

RESEARCH ARTICLE

Genetic machinery which accompanies metaplasticity operates differentially in experimental model of autism

Esra Tufan Benli, Ercan Babur, Nurcan Dursun, Hatice Saray, Özlem Barutçu, Cem Süer, 
  •  1 December 2024

Graphical Abstract

Genetic machinery which accompanies metaplasticity operates differentially in experimental model of autism Issue ,

Investigation of Synaptic Plasticity and Molecular Changes in the Autism Model Induced by VPA.

RESEARCH ARTICLE

Investigation of chromosomal anomalies and copy number variations in children diagnosed with autism spectrum disorder by array CGH method

Fethiye Kılıçaslan, Özlem Öz, Mehmet Burak Mutlu, 
  •  30 November 2024

Graphical Abstract

Investigation of chromosomal anomalies and copy number variations in children diagnosed with autism spectrum disorder by array CGH method Issue ,

This study aimed to identify the chromosomal anomalies and copy number variations (CNVs) in autism spectrum disorder (ASD) and to provide genotype/phenotype correlations. This shows aCGH images of patients with pathogenic or likely pathogenic changes: (a) 70 kb copy number loss in region 22q13.33; (b) 10.1 Mb copy number gain in region 15q13.2q13.3; (c) 6.3 Mb copy number gain in region 3p22.3p22.2; (d) 699 kb copy number gain in region 15q11.2q12; and (e) 500 kb copy number loss in region 15q11.2.

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Articles with the most citations published in the Last 2 Years according to CrossRef. The citation counts listed reflect the total number of all citations to date.

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Open access

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Music alleviates cognitive impairments in an animal model of autism

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Administration of agmatine prior to physical or psychological stress in pregnant mice ameliorates behavioural and cognitive deficits in female offspring

Amin Hassanshahi, Mahyar Janahmadi, Moazamehosadat Razavinasab, Mehran Ilaghi, Kristi A. Kohlmeier, Elham Hassanshahi, Mohammad Shabani, 

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Gut—brain barrier dysfunction bridge autistic‐like behavior in mouse model of maternal separation stress: A behavioral, histopathological, and molecular study

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Effects of prenatal testosterone exposure on the development of autism‐like behaviours in offspring of Wistar rats

Mumin Alper Erdogan, Mehmet Fatih Bozkurt, Oytun Erbas, 
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X‐linked neuronal migration disorders: Gender differences and insights for genetic screening

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