Edited By: Prof. Hansel M. Fletcher
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Molecular Oral Microbiology is a bimonthly journal which publishes high quality research papers and reviews on fundamental or applied molecular studies of microorganisms of the oral cavity and respiratory tract, host-microbe interactions, cellular microbiology, molecular ecology, and immunological studies of oral and respiratory tract infections.
Prof. Hansel M. Fletcher, Editor-in-Chief of Molecular Oral Microbiology.

Dr. Fletcher is currently the Assistant Dean for Graduate Student Affairs in the School of Medicine at Loma Linda University. As part of this portfolio he manages the graduate program including the curriculum. He is also Professor and Vice Chair for the Department of Basic Sciences, Division of Microbiology and Molecular Genetics. He serves on several study panels for the National Institutes of Health, including study sections that evaluate grants for the training and development of graduate students, postdoctoral fellows and faculty at the early stages of their career.
As an experienced and well-trained scientist in the molecular genetics and biochemistry of microbial diseases, his research program has been focused on oral bacterial pathogens important to periodontal diseases and inflammatory systemic diseases including cardiovascular disease and rheumatoid arthritis. His pioneering work on genetic tool development for Porphyromonas lead to the first demonstration of the role of proteases in the virulence of P. gingivalis. Furthermore, the genetic tool (an ermF/ermAM antibiotic resistance cassette) is the most widely used in genetics studies in P. gingivalis.
Read here a more detailed biosketch of Dr. Fletcher.
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Articles
The Effect of Environmental Factors on the Nitrate and Nitrite Metabolism of Oral Actinomyces and Schaalia Species
-  6 February 2025
From Teeth to Body: The Complex Role of Streptococcus mutans in Systemic Diseases
-  27 January 2025
Detection of Amyloid‐β Peptides in Gingival Crevicular Fluid and Its Effect on Oral Pathogens
-  12 December 2024
Decoding Adenine DNA Methylation Effects in Streptococcus Mutans: Insights Into Self-DNA Protection and Autoaggregation
-  3 December 2024
Impact of Periodontal Lipopolysaccharides on Systemic Health: Mechanisms, Clinical Implications, and Future Directions
-  27 November 2024
Graphical Abstract

Summary of the pathways through which periodontal LPS enter systemic circulation, current treatments, and future research directions. Red arrows show the mechanisms of LPS dissemination, blue arrows indicate therapeutic strategies, and green arrows highlight future perspectives, including natural products mitigating the effects of periodontal LPS. Created with BioRender.com.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology
-  409-419
-  21 July 2012
The microbiota associated with successful or failing osseointegrated titanium implants
-  145-151
-  December 1987
The inflammophilic character of the periodontitis‐associated microbiota
-  248-257
-  26 June 2014
Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease
-  113-118
-  19 March 2002
The function of dendritic cells in modulating the host response
-  13-21
-  28 August 2017
Critical review of 16S rRNA gene sequencing workflow in microbiome studies: From primer selection to advanced data analysis
- Molecular Oral Microbiology
-  347-399
-  7 October 2023
Efficacy of Cetylpyridinium Chloride mouthwash against SARS‐CoV‐2: A systematic review of randomized controlled trials
- Molecular Oral Microbiology
-  171-180
-  20 February 2023
Impact of treatment of rheumatoid arthritis on periodontal disease: A review
- Molecular Oral Microbiology
-  199-224
-  16 February 2024
Functional profile of oral plaque microbiome: Further insight into the bidirectional relationship between type 2 diabetes and periodontitis
- Molecular Oral Microbiology
-  62-79
-  31 May 2023
Prevalence of antibiotic resistance genes in the oral cavity and mobile genetic elements that disseminate antimicrobial resistance: A systematic review
- Molecular Oral Microbiology
-  133-153
-  8 June 2022
Glycolanguage of the oral microbiota
- Molecular Oral Microbiology
-  291-320
-  21 March 2024
Graphical Abstract

Oral bacteria speak a sophisticated glycolanguage transmitted through versatile glycoinfrastructure, carbohydrate-active enzymes, and lectins, which contributes decisively to their success in the oral habitat. Deciphering this glycolanguage opens new avenues for novel antibacterials to treat oral diseases.
Gene expression and metabolic activity of Streptococcus mutans during exposure to dietary carbohydrates glucose, sucrose, lactose, and xylitol
- Molecular Oral Microbiology
-  424-441
-  13 July 2023
Role of oral microbiome in oral oncogenesis, tumor progression, and metastasis
- Molecular Oral Microbiology
-  9-22
-  24 November 2022
Strategies for Streptococcus mutans biofilm dispersal through extracellular polymeric substances disruption
- Molecular Oral Microbiology
-  1-8
-  2 November 2021
Recent issues
- Volume 39, Issue 4
Special Issue: “Regulation of metabolism and inflammation: Links with oral and systemic health” Part III Emerging concepts from pathogenesis to therapy
i-iv, 153-259August 2024Ping Zhang, Sinem Esra Sahingur, Shauna Culshaw