This study reports age-related changes in a wide range of behaviors in male C57BL/6J mice from young to old age. The findings provide basic information about the behavioral characteristics of young, middle-aged, and aged male C57BL/6J mice.

The post COVID-19 manifestations including anhedonia and fatigue are very commonly reported in the duration after recovery ,they may affect the different domains of life,also these post COVID-19 manifestions are negatively associated to the duration.

In Syngap1^−/+ mice, a well-known model of SYNGAP-related ID, we could reproduce most of the previously reported cognitive and emotional deficits. The decreased sensitivity to painful stimuli and impaired motor function that we found in Syngap1^−/+ mice are consistent with the common characteristics of patients with SYNGAP-related ID. We further confirmed that the Syngap1 heterozygote mouse recapitulates the symptoms of ID and ASD patients.

This study investigated the effects of stress exposure via two types of restraint apparatuses, a well-ventilated plastic conical tube and a tapered plastic film envelope, on body weights, behaviors, and plasma corticosterone levels in male BALB/cAJcl mice. Film-restraint stress had more pronounced effects on body weight, depression-related behavior, and corticosterone response than tube-restraint stress, which may help guide which restraint stress procedures to use in generating animal models of stress-induced disorders.