Editor-in-Chief: Irem Bayindir-Buchhalter
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Advanced NanoBiomed Research, part of the prestigious Advanced portfolio, serves as an open access journal for cutting-edge nanomedicine, tissue engineering and biomaterials research aimed at improving human health.
We welcome your manuscripts with a strong focus on healthcare applications of materials science, nanotechnology, biofabrication and biointerfaces.
The Advanced portfolio from Wiley is a family of globally respected, high-impact journals that disseminates the best science from well-established and emerging researchers so they can fulfill their mission and maximize the reach of their scientific discoveries.
Advanced NanoBiomed Research just received a first Journal Citation Indicator of 0.38 and first Journal Impact Factor™ of 3.4. Thank you to all Authors, Reviewers, and other contributors!
On the Cover
Articles
Biomaterial‐Based Gene Delivery to Central Nervous System Cells for the Treatment of Spinal Cord Injury
-  10 September 2023
Graphical Abstract

Spinal cord injury is a catastrophic injury that leads to long-term disability. This review discusses nonviral gene therapy approaches that have been employed to promote repair after injury. Through the targeting of different cells and pathways, this state-of-the-art strategy can revolutionize treatment by simultaneously promoting survival and axon regrowth attenuating scarring, and reducing inflammation, ultimately restoring function to the patient.
Development of 3D‐Printed Magnetic Micro‐Nanorobots for Targeted Therapeutics: the State of Art
-  8 September 2023
Graphical Abstract

Micro-/nanorobots show great potential in enabling innovative bio-applications. The developments in magnetic micro-/nanorobots regarding their materials, fabrications, actuations, and applications are discussed in this article. Herein, it is aimed to discover the limitations of the existing works and to identify the knowledge gap, thereby deriving future directions on magnetic micro-/nanorobots, especially for their applications in targeted therapeutic delivery.
Bioresorbable Insertion Aids for Brain Implantable Flexible Probes: A Comparative Study on Silk Fibroin, Alginate, and Disaccharides
-  7 September 2023
Graphical Abstract

Implantable Probes
As miniaturized, flexible, and biocompatible implantable neural probes seek to circumvent the foreign body response, the problem of surgical implantation due to buckling remains. Multiple bioresorbable insertion aids are investigated in article number 2200117 by Hadi Heidari and co-workers through mechanical, chemical and dissolution characterizations to determine their viability as stiffening coatings for novel flexible neural probes.
Engineered Extracellular Vesicles from Human Skin Cells Induce Pro-β-Cell Conversions in Pancreatic Ductal Cells
-  5 September 2023
Graphical Abstract

Engineered EVs derived from primary human and mouse dermal fibroblasts are used as effective carriers to deliver pancreatic endocrine cell-patterning factors (Pdx1, Ngn3, and MafA—PNM). Engineered EVs can induce direct reprogramming of exocrine/ductal tissue in the pancreas, both in vitro and in vivo; and provide a novel platform technology for nonviral reprogramming-based cell therapies for insulin-dependent diabetes.
Multichamber PLGA Microparticles with Enhanced Monodispersity and Encapsulation Efficiency Fabricated by a Batch‐Microfluidic Hybrid Approach
-  5 September 2023
Graphical Abstract

A batch-microfluidic hybrid approach that can fabricate multichamber PLGA microparticles is presented. The multichambered PLGA microparticles prepared by the hybrid method exhibit high monodispersity, improved encapsulation efficiency, size controllability, and sustained drug release profiles without initial burst release.
The following is a list of the most cited articles based on citations published in the last three years, according to CrossRef.
Lipid Nanoparticles for Drug Delivery
-  25 November 2021
Graphical Abstract

This article reviews the classification of different lipid nanoparticles, and their preparation and characterization. Their applications in encapsulating and delivering hydrophobic drugs, hydrophilic drugs, and RNAs for different diseases and how lipid nanoparticles enable nanomedicine to address the challenges of blood–brain barrier, targeted delivery, and various routes of administration are also discussed .
Natural and Synthetic Bioinks for 3D Bioprinting
-  30 March 2021
Graphical Abstract

Herein, various bioprinting methods are discussed briefly and then natural and synthetic polymers or hybrid biomaterials are presented with respect to their rheological, mechanical, and biological properties that are essential for successful 3D bioprinting. The future challenges and critical considerations concerning the translation of bioprinting technique are also discussed.
Considerations for Size, Surface Charge, Polymer Degradation, Co‐Delivery, and Manufacturability in the Development of Polymeric Particle Vaccines for Infectious Diseases
-  17 December 2020
Graphical Abstract

Properties such as size, surface charge, degradation rate, and the co-delivery of antigen and adjuvant all affect the immune responses of polymeric particle vaccines for infectious disease. A review of current and past literature reveals these effects vary with polymer type, antigen, adjuvant, and route of administration. Vaccine manufacturing methods also impact efficacy, scalability, and marketability.
Recent Strategies for Strengthening and Stiffening Tough Hydrogels
-  13 May 2021
Graphical Abstract

Strengthening and stiffening tough double-network (DN) or polyampholyte (PA) hydrogels are a promising approach to fabricate synthetic hydrogels emulating the natural load-bearing tissues with elastic moduli in the MPa-to-GPa. Herein, several strategies for strengthening and stiffening the hydrogels are summarized, and their reinforcing and fracture mechanisms are outlined, providing future directions to develop hydrogels with desirable mechanical properties.
Air−Liquid Interface Cultures of the Healthy and Diseased Human Respiratory Tract: Promises, Challenges, and Future Directions
-  6 May 2021
Graphical Abstract

Air−liquid interface cultures are used to accurately mimic the human respiratory tract. Different cell types are combined to create a complex in vitro environment. Furthermore, the interaction with different pathogens such as viruses or bacteria can be simulated. Thereby, they represent a useful tool for drug testing and help reduce animal experimentation.