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Join our community of authors and benefit from:
- An easy-to-use manuscript submission system, without manuscript formatting requirements
- Dedicated editors who are active in their specific communities
- High editorial standards, ensuring all published manuscripts undergo an in-depth peer review process
- Quick, efficient publication with full transparency on all publishing metrics and turnaround times
- Greater impact, reach, and visibility of your research through open access
- Retention of all ownership and copyright of your published research
Language editing and author services
Wiley Editing Services offers expert help with article preparation, including English Language Editing, translation, manuscript formatting, figure illustration, figure formatting, and graphical abstract design - so you can submit your manuscript with confidence.
Submission
At submission you will need to register for a Wiley Researcher ID if you do not already have one (no need to create a new account if you have previously submitted to a Wiley journal or used Wiley Online Library). You will be asked to upload your manuscript file which will automatically be scanned and displayed for you to verify and confirm before submitting. Please note that author details and emails for all co-authors are required at the point of submission. Your manuscript will then be sent on for editorial evaluation and peer review. For technical help, please contact [email protected].
Terms of submission
Manuscripts must be submitted on the understanding that they are not published, in press, or submitted elsewhere (with the exception that articles are permitted to be submitted to preprint servers) The submitting author is responsible for ensuring that the article's publication has been approved by all the other co-authors. It is also the submitting author's responsibility to ensure that the article has all necessary institutional approvals. Only an acknowledgment from the editorial office officially establishes the date of receipt. Further correspondence and proofs will be sent to the author(s) before publication, unless otherwise indicated. It is a condition of submission that the authors permit editing of the manuscript for readability. All submissions are bound by the publisher's terms of service.
Peer review
The journal follows a single-anonymized peer review model, for applicable article types. Information on the Peer Review model can be found here.
Wiley's policy on the confidentiality of the review process is available here.
All submitted articles are subject to assessment and peer review to ensure editorial appropriateness and technical correctness.
Research published in the journal must be:
- Scientifically valid - adhering to accepted community standards of research.
- Technically accurate in its methods and results.
- Representative of a specific advance, or replication, or null/negative result, which is worthy of publication.
- As reproducible as possible - sharing underlying data, code, and supporting materials wherever able.
- Ethically sound and transparent - adhering to best practice with respect to animal and human studies, consent to publish, and clear declaration of potential conflicts of interests, both real and perceived.
In the spirit of sharing findings through our open science mission, emphasis is not placed on novelty, interest, or perceived impact. Replication studies, particularly of research published in this journal, are encouraged.
In order for an article to be accepted for publication, the assigned editor will first consider if the manuscript meets the minimum editorial standards and fits within the scope of the journal. If an article is considered suitable for the journal, the editor will ideally solicit at least two external peer reviewers (who will remain anonymous to the authors unless they choose to disclose their identity by signing the review report) to assess the article before confirming a decision to accept. Decisions to reject are at the discretion of the editor.
Our research integrity team will occasionally seek advice outside standard peer review, for example, on submissions with serious ethical, security, biosecurity, or societal implications. We may consult experts and the editor before deciding on appropriate actions, including but not limited to: recruiting reviewers with specific expertise, assessment by additional editors, and declining to further consider a submission.
Special Issues
Special Issues are subject to extensive review, during which journal Editors or Editorial Board input is solicited for each proposal. Our approval process includes an assessment of the rationale and scope of the proposed topic(s), and the expertise of Guest Editors, if any are involved. Special Issue articles must follow the same policies as described in the journal's Author Guidelines.
Editor/Editorial Board papers
Papers authored by Editors or Editorial Board members of the title are sent to Editors that are unaffiliated with the author or institution and monitored carefully to ensure there is no peer review bias.
Concurrent submissions
In order to ensure sufficient diversity within the authorship of the journal, authors will be limited to having three manuscripts under review at any point in time. If an author already has three manuscripts under review in the journal, they will need to wait until the review process of at least one of these manuscripts is complete before submitting another manuscript for consideration. This policy does not apply to editorials or other non-peer-reviewed manuscript types.
Article processing charges
The journal is open access. Article processing charges (APCs) allow the publisher to make articles immediately available online to anyone to read and reuse upon publication.
Preprints
The journal accepts articles previously published on preprint servers, and does not consider this to compromise the novelty of the results. Articles based on content previously made public only on a preprint server, institutional repository, or in a thesis will be considered. The preprint should be cited.
Clinical Trials
When publishing clinical trials, the journal aims to comply with the recommendations of the International Committee of Medical Journal Editors (ICMJE) on trial registration. Therefore, authors are requested to register the clinical trial presented in the manuscript in a public trial registry and include the trial registration number at the end of the abstract. Trials should be registered prospectively before patient recruitment has begun. Where this has not happened, the study must be registered retrospectively, and the date of registration should be clearly stated in the manuscript.
Preregistration of studies
Authors are encouraged to indicate whether the conducted research was preregistered in an independent, institutional registry (e.g., http://clinicaltrials.gov/, https://www.socialscienceregistry.org/, http://osf.io/, https://egap.org/registry/, http://ridie.3ieimpact.org/). Preregistration of studies involves registering the study design, variables, and treatment conditions prior to conducting the research.
Preregistration of analysis plans
Authors are encouraged to indicate whether or not the conducted research was preregistered with an analysis plan in an independent, institutional registry (e.g., http://clinicaltrials.gov/, https://www.socialscienceregistry.org/, http://osf.io/, https://egap.org/registry/, http://ridie.3ieimpact.org/). Preregistration of studies involves registering the study design, variables, and treatment conditions. Including an analysis plan involves specification of sequence of analyses or the statistical model that will be reported.
ORCID
At submission, an ORCID iD must be provided for the submitting author(s). If you already have an ORCID iD, you will be asked to provide it.
Article types
The journal will consider the following article types:
Research articles
Research articles should present the results of an original research study. These manuscripts should describe how the research project was conducted and provide a thorough analysis of the results of the project. Systematic reviews may be submitted as research articles.
Reviews
A review article provides an overview of the published literature in a particular subject area.
Formatting
The manuscript should be an editable doc./.docx file including text and tables. Please provide figures in the highest resolution possible, whether this means they are embedded or provided separately.
Note: If the manuscript, figures, or tables are difficult for you to read, they will also be difficult for the editors and reviewers, and the editorial office will send them back for revision.
We recommend that all manuscripts include line numbers and follow the structure below:
Title and authorship information
The following information should be included:
- Manuscript title
- Full author names
- Full institutional mailing addresses
- Email addresses
Affiliations. The publisher remains neutral with regard to jurisdictional claims in institutional affiliations. Responsibility for affiliations ultimately rests with the author, although the publisher may request changes be made to countries listed in affiliations to ensure consistency across published output (for indexing and discovery reasons).
Abstract
The manuscript should contain an abstract. The abstract should be self-contained, citation-free, and should not exceed 300 words.
Introduction
This section should be succinct, with no subheadings.
Materials and methods
The methods section should provide enough detail for others to be able to replicate the study. If you have more than one method, use subsections with relevant headings, e.g. different models, in vitro and in vivo studies, statistics, materials and reagents, etc.
The journal has no space restriction on methods. Detailed descriptions of the methods (including protocols or project descriptions) and algorithms may also be uploaded as supplementary information or a previous publication that gives more details may be cited. If the method from a previous article is used then this article must be cited and discussed. If wording is reused from a published article then this must be noted, e.g. This study uses the method of Smith et al. and the methods description partly reproduces their wording [1].
If a method or tool is introduced in the study, including software, questionnaires, and scales, the license this is available under and any requirement for permission for use should be stated. If an existing method or tool is used in the research, the authors are responsible for checking the license and obtaining any necessary permission. If permission was required, a statement confirming permission was granted should be included in the materials and methods section.
Publishing protocols. We encourage authors describing any methodology, in particular laboratory-based experiments in the life sciences but also computational and bioinformatics protocols, to upload details of their methods to protocols.io. This is an open access website that allows researchers to record their methods in a structured way, obtain a DOI to allow easy citation of the protocol, collaborate with selected colleagues, share their protocol privately for journal peer review, and choose to make it publicly available. Once published, the protocol can be updated and cited in other articles.
You can make your protocol public before publication of your article if you choose, which will not harm the peer review process of your article and may allow you to get comments about your methods to adapt or improve them before you submit your article (see also the protocols.io FAQ page).
Results and discussion
This section may be divided into subsections or may be combined.
Main text (review only)
This section may be divided into subsections or may be combined.
Conclusions
This should clearly explain the main conclusions of the article, highlighting its importance and relevance.
Data availability
Authors must include a data availability statement with their submission.
When submitting a manuscript, submitting authors will be asked to select from several pre-written statements or use the text editor to tell us about data availability with regard to their submission. Review our Data Sharing Policy to understand which data availability statement is right for your submission.
Conflicts of interest
Authors must declare all relevant interests that could be perceived as conflicting. Authors should explain why each interest may represent a conflict. If no conflicts exist, the authors should state this. Submitting authors are responsible for co-authors declaring their interests.
Conflicts of interest (COIs, also known as 'competing interests') occur when issues outside research could be reasonably perceived to affect the neutrality or objectivity of the work or its assessment. For more information, see our publication ethics policy. Authors must declare all potential interests - whether or not they actually had an influence - in the conflicts of interest section, which should explain why the interest may be a conflict. If there are none, the authors should state: "The author(s) declare(s) that there is no conflict of interest regarding the publication of this article". Submitting authors are responsible for co-authors declaring their interests. Declared conflicts of interest will be considered by the editor and reviewers, and included in the published article.
Authors must declare current or recent funding (including for article processing charges) and other payments, goods or services that might influence the work. All funding, whether a conflict or not, must be declared in the funding statement. The involvement of anyone other than the authors who: i) has an interest in the outcome of the work; ii) is affiliated to an organization with such an interest; or iii) was employed or paid by a funder, in the commissioning, conception, planning, design, conduct, or analysis of the work, the preparation or editing of the manuscript, or the decision to publish must be declared.
You may be asked to make certain changes to your manuscript as a result of your declaration. These requests are not an accusation of impropriety. The editor or reviewer is helping you to protect your work against potential criticisms.
If you are in any doubt about declaring a potential conflict, remember that if it is revealed later - especially after publication - it could cause more problems than simply declaring it at the time of submission. Undeclared conflicts of interest could lead to a corrigendum or, in the most serious cases, a retraction.
Funding statement
Authors must state how the research and publication of their article was funded, by naming financially supporting body(s) (written out in full) followed by associated grant number(s) in square brackets (if applicable), for example: "This work was supported by the Engineering and Physical Sciences Research Council [grant numbers xxxx, yyyy]; the National Science Foundation [grant number zzzz]; and a Leverhulme Trust Research Project Grant".
If the research did not receive specific funding, but was performed as part of the employment of the authors, please name this employer. If the funder was involved in the manuscript writing, editing, approval, or decision to publish, please declare this.
Acknowledgments
All acknowledgments (if any) should be included at the very end of the manuscript before the references. Anyone who made a contribution to the research or manuscript, but who is not a listed author, should be acknowledged (with their permission).
References
Authors may submit their references in any style. If accepted, these will be reformatted in Chicago style by the publisher. Authors are responsible for ensuring that the information in each reference is complete and accurate. All references should be numbered consecutively in the order of their first citation. Citations of references in the text should be identified using numbers in square brackets e.g., "as discussed by Smith [9]"; "as discussed elsewhere [9, 10]". All references should be cited within the text and uncited references will be removed.
Citation standards. All data, program code, and other methods should be appropriately cited. Such materials should be recognized as original intellectual contributions and afforded recognition through citation.
Date formatting
Dates should be written out fully to avoid confusion with different all-numeral date styles. For example, 11/10/2018 could be 10 November 2018 or 11 October 2018 depending on the reader, therefore, the date should be written out in full. For example, the date September 1, 2018 should be used rather than 01/09/2018 or 09/01/2018.
Units of measurement
Units of measurement should be presented simply and concisely using the International System of Units (SI).
Preparation of figures
Upon submission of an article, authors should include all figures and tables in the file of the manuscript. If the article is accepted, authors will be asked to provide the source files of the figures. Each figure should be supplied in a separate electronic file. All figures should be cited in the manuscript in a consecutive order. Figures should be supplied in either vector art formats (Illustrator, EPS, WMF, FreeHand, CorelDraw, PowerPoint, Excel, etc.) or bitmap formats (Photoshop, TIFF, GIF, JPEG, etc.). Bitmap images should be of 300 dpi resolution at least unless the resolution is intentionally set to a lower level for scientific reasons. If a bitmap image has labels, the image and labels should be embedded in separate layers.
Maps. The publisher remains neutral with regard to jurisdictional claims in published maps. For reasons of consistency, authors are requested to use accepted standard maps as the basis for map figure drawing, for example using the latest standard base-map of Map Press. Responsibility for maps rests with the author and it is their responsibility to also provide any copyright or licence information when using maps that are not owned or created by the author (e.g. Google Maps, etc.)
Preparation of tables
Tables should be cited consecutively in the text. Every table must have a descriptive title and if numerical measurements are given, the units should be included in the column heading. Vertical rules should not be used.
Supplementary materials are the additional parts to a manuscript, such as audio files, video clips, or datasets that might be of interest to readers. A section titled supplementary material should be included before the references list with a concise description for each supplementary material file. Supplementary materials are not modified by our production team. Authors are responsible for providing the final supplementary material files that will be published along with the article.
Proofs
Corrected proofs must be returned to the publisher within two to three days of receipt. The publisher will do everything possible to ensure prompt publication.
Copyright and permissions
Authors retain the copyright of their manuscripts, and all open access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. The submitting author is responsible for securing any permissions needed for the reuse of copyrighted materials included in the manuscript.
While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.
Reporting guidelines
Authors are strongly encouraged to use appropriate reporting guidelines when preparing and submitting manuscripts, to maximize transparency and reproducibility. Our editors and reviewers are also encouraged to use them in the review process. Completed checklists should be provided in the supplementary files on submission. We particularly encourage the use of:
- CONSORT for randomized controlled trials
- TREND for non-randomized trials
- PRISMA for systematic review and meta-analyses
- CARE for case reports
- STROBE for observational studies
- STREGA for genetic association studies
- SRQR for qualitative studies
- STARD for diagnostic accuracy studies
- ARRIVE for animal experiments
Small molecule single crystal X-ray diffraction data
We recommend the use of SHELXL (2014 or later) for data processing, which embeds both the results file and structure factors into the finalized crystallographic information file (CIF) (see http://journals.iucr.org/c/services/shelxl.html for more information).
We strongly encourage that all new small molecule single crystal X-ray diffraction data be deposited with the Cambridge Crystallographic Data Centre (CCDC; https://www.ccdc.cam.ac.uk/deposit) prior to submission of your article. The CCDC number(s) assigned to your structure(s) should be listed in the data availability statement, which permits retrieval of the crystallographic data for peer review purposes, and allows readers to find them once the article is published.
We would also ask you to check the integrity of your data using the IUCr's checkCIF service (available here: http://checkcif.iucr.org/), and address significant unresolved problems (typically all A- and B-alerts) in the Validation Response Form portion of the CIF. The generation of the checkCIF report and the response to A- and B-alerts can also all be done through the deposition to the CCDC.
If you choose to not deposit your data in the CCDC prior to submission, you must upload your CIF (and RES and HKL/FCF files if necessary), along with a PDF of the checkCIF report (link above) as supporting information, at the same as uploading your manuscript. At acceptance, you should then submit your crystal data to an appropriate repository, and update the data availability statement in your manuscript to indicate how authors can retrieve the data.
The data availability section should reference crystallographic data in the following format: "Crystallographic data for the structures reported in this manuscript have been deposited with the Cambridge Crystallographic Data Centre under the CCDC numbers: xxxxxx (Compound name 1), xxxxxx (Compound name 2), and xxxxxx (Compound name 3). Copies of these data can be obtained free of charge from http://www.ccdc.cam.ac.uk/data_request/cif."
Ethical guidelines
For any experiments on humans, all work must be conducted in accordance with the Declaration of Helsinki (1964) Manuscripts describing experimental work that carries a risk of harm to human subjects must include a statement that the experiment was conducted with the human subjects' understanding and written informed consent, as well as a statement that the responsible ethics committee has approved the experiments.
In the case of any animal experiments, the authors must provide a full description of any anaesthetic or surgical procedure used, as well as evidence that all possible steps were taken to avoid animal suffering at each stage of the experiment. Approval must be obtained from the relevant ethics committee/Institutional Animal Care and Use Committee where required.
This journal uses iThenticate’s CrossCheck software to detect instances of overlapping and similar text in submitted manuscripts. Read Wiley’s Top 10 Publishing Ethics Tips for Authors and Wiley’s Publication Ethics Guidelines.
Appeals
Authors may appeal if they feel that the decision to reject was based on: i) a major misunderstanding over a technical aspect of the manuscript; or ii) a failure to understand the scientific advance shown by the manuscript. Appeals requesting a second opinion without sufficient justification will not be considered. To lodge an appeal, please contact the journal by email, quoting your manuscript number. Appeals will only be considered from the original submitting author.