1. Submission and Peer Review Process
  2. Article Types
  3. After Acceptance 

1. Submission and Peer Review Process

Once the submission materials have been prepared in accordance with the Author Guidelines, manuscripts should be submitted online at 


For help with submissions, please contact: [email protected] 

This journal does not charge submission fees. 


Article Preparation Support  

Wiley Editing Services offers expert help with English Language Editing, as well as translation, manuscript formatting, figure illustration, figure formatting, and graphical abstract design – so you can submit your manuscript with confidence.  

Also, check out our resources for Preparing Your Article for general guidance about writing and preparing your manuscript. 


Free format submission 

Acta Physiologica save your time by using Free Format submission for a simplified and streamlined submission process.  

Before you submit, you will need: 

  • Your manuscript: this should be an editable file including text, figures, and tables, or separate files—whichever you prefer. All required sections should be contained in your manuscript, including abstract, introduction, methods, results, and conclusions. Figures and tables should have legends. Figures should be uploaded in the highest resolution possible. If the figures are not of sufficiently high quality your manuscript may be delayed. References may be submitted in any style or format, as long as it is consistent throughout the manuscript. Supporting information, such as cover letters, should be submitted in separate files. If the manuscript, figures, or tables are difficult for you to read, they will also be difficult for the editors and reviewers, and the editorial office will send it back to you for revision. Your manuscript may also be sent back to you for revision if the quality of English language is poor. 
  • An ORCID ID, freely available at (Why is this important? Your article, if accepted and published, will be attached to your ORCID profile. Institutions and funders are increasingly requiring authors to have ORCID IDs.) 
  • The title page of the manuscript, including:
    • Your co-author details, including affiliation and email address. (Why is this important? We need to keep all co-authors informed of the outcome of the peer review process.)
    • Statements relating to our ethics and integrity policies, which may include any of the following (Why are these important? We need to uphold rigorous ethical standards for the research we consider for publication):
      • data availability statement
      • funding statement
      • conflict of interest disclosure
      • ethics approval statement
      • patient consent statement
      • permission to reproduce material from other sources
      • clinical trial registration 


Open Access 

This journal is a subscription journal that offers an open access option. You’ll have the option to choose to make your article open access after acceptance, which will be subject to an APC, unless a waiver applies. For more information on this journal’s APCs, please see the Open Access page.


Preprint policy  

Please find the Wiley preprint policy here. 

Acta Physiologica will consider for review articles previously available as preprints. You may also post the submitted version of a manuscript to a preprint server at any time. You are requested to update any pre-publication versions with a link to the final published article.


Data Sharing and Data Availability 

This journal expects and peer reviews data sharing. Review Wiley’s Data Sharing policy where you will be able to see and select the data availability statement that is right for your submission. 


Data Citation  

Please review Wiley’s Data Citation policy. 


Data Protection 

By submitting a manuscript to or reviewing for this publication, your name, email address, and affiliation, and other contact details the publication might require, will be used for the regular operations of the publication. Please review Wiley’s Data Protection Policy to learn more. 



You should list all funding sources in the Acknowledgments section. You are responsible for the accuracy of their funder designation. If in doubt, please check the Open Funder Registry for the correct nomenclature. 



All listed authors should have contributed to the manuscript substantially and have agreed to the final submitted version. Review editorial standards and scroll down for a description of authorship criteria.


Author Pronouns  

Authors may now include their personal pronouns in the author bylines of their published articles and on Wiley Online Library. Authors will never be required to include their pronouns; it will always be optional for the author. Authors can include their pronouns in their manuscript upon submission and can add, edit, or remove their pronouns at any stage upon request. Submitting/corresponding authors should never add, edit, or remove a coauthor’s pronouns without that coauthor’s consent. Where post-publication changes to pronouns are required, these can be made without a correction notice to the paper, following Wiley’s Name Change Policy to protect the author’s privacy. Terms which fall outside of the scope of personal pronouns (e.g., proper or improper nouns), are currently not supported. 



This journal requires ORCID. Please refer to Wiley’s resources on ORCID. Acta Physiologica requires the Corresponding Author and Senior Author to provide their ORCID ID.  


Reproduction of Copyright Material 

If excerpts from copyrighted works owned by third parties are included, credit must be shown in the contribution. It is your responsibility to also obtain written permission for reproduction from the copyright owners. For more information visit Wiley’s Copyright Terms & Conditions FAQ. 

The corresponding author is responsible for obtaining written permission to reproduce the material "in print and other media" from the publisher of the original source, and for supplying Wiley with that permission upon submission. 


Title Page  

The title page should contain: 

  1. A brief informative title containing the major key words. The title should not contain abbreviations or symbols (see Wiley's best practice SEO tips);  
  2. A short running title of less than 40 characters (including spaces); 
  3. The full names of the authors;  
  4. The author's institutional affiliations where the work was conducted, with a footnote for the author’s present address if different from where the work was conducted;  
  5. The animal species should appear in the title; 
  6. Acknowledgments. 


Main Text File 

Manuscripts can be uploaded either as a single document (containing the main text, tables, and figures), or with figures and tables provided as separate files. Should your manuscript reach revision stage, figures and tables must be provided as separate files. The main manuscript file can be submitted in Microsoft Word format. The main text file should be in Word format. 


Your main document file should include: 

  • A short informative title not exceeding 40 letters (spaces are included). The title should contain the major key words. The title should contain up to seven keywords and should not contain abbreviations or symbols; 
  • The full names of the authors with institutional affiliations (department, institution, and country) where the work was conducted, with a footnote for the author’s present address if different from where the work was conducted;  
  • Acknowledgments; 
  • Abstract (structured Aim, Methods, Results and Conclusion). The abstract should not exceed 250 words and should briefly and concisely describe the aim of the investigation, the methods used, the results including quantitative figures and the conclusions drawn. Novel aspects and physiological relevance should be emphasized. Do not use abbreviations or symbols in the abstract.  
  • Up to seven keywords;
  • Practitioner Points (optional at first submission) Authors will need to provide no more than 3 ‘key points’, written with the practitioner in mind, that summarize the key messages of their paper to be published with their article. 
  • Main body: formatted as introduction, results, discussion, materials & methods, conclusion
  • Conflict of interest
  • References;
  • Tables (each table complete with title and footnotes); 
  • Figure legends: Legends should be supplied as a complete list in the text. Figures should be uploaded as separate files (see below). 


Preferred Main Text Formatting 

As the journal offers Free Format submission, the following guidelines are recommendations and will not be required at submission: 

  • Manuscripts should be formatted double-spaced with no hyphenation and automatic word-wrap (no hard returns within paragraphs). 
  • Please type your text consistently, e.g., take care to distinguish between '1' (one) and 'l' (lower-case L) and '0' (zero) and 'O' (capital O).
  • Please do not use carriage returns at the end of lines within a paragraph. Turn hyphenation option off.
  • All pages should be correctly numbered at the top, right-hand corner, beginning with the title page. 


Conflict of Interest 

A conflict of interest exists when professional judgment concerning a primary interest (such as patients’ welfare or the validity of research) may be influenced by a secondary interest (such as financial gain) (ICMJE, 2013). This occurs, for example, when an author or the author's institution has financial or personal relationships with other people or organizations that inappropriately influence (bias) his or her actions. 

Financial relationships are easily identifiable, but conflicts can also occur because of personal relationships, academic competition, or intellectual passion. A conflict can be actual or potential, perceptions of conflict of interest are as important as actual conflicts of interest and full disclosure to the Editor is mandatory. 

All submissions to Acta Physiologica must include disclosure of all relationships that could be viewed as presenting a potential conflict of interest. If there are no conflicts of interest, authors should state that there are none. 

Clinical Trial Registration 

Clinical trials are studies that prospectively assign human beings to either intervention/treatment or control groups, usually to report clinical/health-related outcomes. Prior to subject enrolment, all clinical trials must be registered in a public clinical trials registry. Trial identification numbers and registry URLs must be provided in the manuscript. Appropriate clinical trials registries provide, free of charge, public information on the trial and are managed by independent not-for-profit providers, examples include ISRCTN, UMIN-CTR, Australian-New Zealand Clinical Trials Registry, Netherlands Trial Registry, a primary register of WHO International Clinical Trials Registry Platform or 

Reference Style 

As the journal offers Free Format submission, you do not need to format the references in your article. This will instead be taken care of by the typesetter. However, we do recommend the use of a tool such as EndNote or Reference Manager to assist with reference management. 


Figures and Supporting Information 

Figures, supporting information, and appendices should be supplied as separate files. You should review the basic figure requirements for manuscripts for peer review, as well as the more detailed post-acceptance figure requirements 

Please note that authors will be asked to apply Acta Physiologica’s 2021 ‘Guidelines to figures’ at revision stage. View Wiley’s FAQs on supporting information. 

As Acta Physiologica offers Free Format submission, the following recommendations for Electronic Artwork, Tables and Mathematics are only required at revision and do not need to be included at initial submission. 

Electronic Artwork 

We would like to receive your artwork in electronic form. Please save vector graphics (e.g., line artwork) in Encapsulated Postscript Format (EPS), and bitmap files (e.g., half-tones) in Tagged Image File Format (TIFF). Ideally, vector graphics that have been saved in metafile (.WMF) or pict (.PCT) format should be embedded within the body of the text file. Detailed information on our digital illustrations standards is available here. 



Tables should be double-spaced on separate pages. Each table should have three dividing lines to separate the titles and data. No vertical rules should be used. Tables should ideally be created in a word processor table editor. Avoid including multiple data in single table cells. 



In-line equations should be typed as text. The use of graphics programs and 'equation editors' should be taken with care. Displayed equations (unless prepared by the MathType Equation Editor) may be re-keyed by our typesetter. 


Peer Review  

This journal operates under a single-blind peer review model. Except where otherwise stated, manuscripts are peer reviewed by at least two anonymous reviewers and an Associate or Assistant Editor. Papers will only be sent to review if the Editor-in-Chief determines that the paper meets the appropriate quality and relevance requirements. 

In-house submissions, i.e., papers authored by Editors or Editorial Board members of the title, will be sent to Editors unaffiliated with the author or institution and monitored carefully to ensure there is no peer review bias. 

Wiley's policy on the confidentiality of the review process is available here. 


Refer and Transfer Program 

Wiley believes that no valuable research should go unshared. This journal participates in Wiley’s Refer & Transfer program. If your manuscript is not accepted, you may receive a recommendation to transfer your manuscript to another suitable Wiley journal, either through a referral from the journal’s editor or through our Transfer Desk Assistant.  

Author Contributions 

For all articles, the journal mandates the CRediT (Contribution Roles Taxonomy)—more information is available on our Author Services site. 


Genomic and/or Proteomic high-throughput studies 

High-throughput data (genomic or proteomic, e.g., microarrays or next-generation sequencing) must comply with minimum information about a microarray experiment (MIAME) criteria. Editors and reviewers must be able to access the data at the time of submission, e.g., through the provision of a GEO, ArrayExpress or CYBEX accession number. Upon acceptance, data must be publicly available, and no more amendments to the data must be made. 


Guidelines for Nucleic Acid and Protein Sequence reporting 

If a manuscript reports novel protein or nucleotide sequences, authors are requested to, prior to submission, upload the sequence information to GenBank, EMBL, or the DNA Databank of Japan, and provide an accession number in the manuscript upon submission. Upon acceptance, data must be publicly available, and no more amendments to the data must be made. 


Guidelines on Publishing and Research Ethics in Journal Articles 

The journal requires that you include in the manuscript details IRB approvals, ethical treatment of human and animal research participants, and gathering of informed consent, as appropriate. You will be expected to declare all conflicts of interest, or none, on submission. Please review Wiley’s policies surrounding human studies, animal studies, clinical trial registration, biosecurity, and research reporting guidelines. 

This journal follows the core practices of the Committee on Publication Ethics (COPE) and handles cases of research and publication misconduct accordingly (  

This journal uses iThenticate’s CrossCheck software to detect instances of overlapping and similar text in submitted manuscripts. Read Wiley’s Top 10 Publishing Ethics Tips for Authors and Wiley’s Publication Ethics Guidelines 


2. Article Types

Article Type 



Suggested Word Limit*  

Abstract / Structure 

Other Requirements 







Research Paper 


reports of new research findings or conceptual analyses that make a significant contribution to knowledge 

3500 limit  

Yes, Structured  

Data Availability Statement 

IRB Statement 

Review Article 


critical reviews of the literature, including systematic reviews and meta-analyses 

5000 limit 

Yes, unstructured 




brief and concise description of the aim of the investigation, the methods used, the results of the investigation and the conclusions drawn. Novel aspects and physiological relevance should be emphasized 

1500 limit 

Yes, structured 

Data Availability Statement 

IRB Statement 



short, invited opinion pieces that discuss an issue of immediate importance to the research community 

1000 limit 





important, ancillary information, which is relevant to the parent article, but that would be inappropriate or impractical to include in the article itself 




 *Papers significantly exceeding the Word Limit should be queried with the Editorial Office. Explanations for being significantly over the Word Limit may be included in the Covering Letter.

3. After Acceptance

First Look 

After your paper is accepted, your files will be assessed by the editorial office to ensure they are ready for production. You may be contacted if any updates or final files are required. Otherwise, your paper will be sent to the production team. 


Wiley Author Services 

When an accepted article is received by Wiley’s production team, the corresponding author will receive an email asking them to login or register with Wiley Author Services. You will be asked to sign a publication license at this point as well as pay for any applicable APCs. 


Copyright & Licensing 

You may choose to publish under the terms of the journal’s standard copyright agreement, or Open Access under the terms of a Creative Commons License.  

Standard re-use and licensing rights vary by journal. Note that certain funders mandate a particular type of CC license be used. This journal uses the CC-BY Creative Commons License. 

Self-Archiving Definitions and Policies: Note that the journal’s standard copyright agreement allows for self-archiving of different versions of the article under specific conditions. 



Authors will receive an e-mail notification with their proofs included as an Adobe Acrobat pdf. The e-mail server must be able to accept attachments up to 4 MB in size. Acrobat Reader will be required to read this file. This software can be downloaded (free of charge) from the following Web site: 

This will enable the file to be opened, read on screen, and printed out for any corrections to be added. Further instructions will be sent with the proof. Proofs must be returned within 48 hours of receipt of the email. Proofs will be posted if no e-mail address is available; in your absence, please arrange for a colleague to access your e-mail to retrieve the proofs. 

Authors should also make sure that any renumbered tables, figures, or references match text citations and that figure legends correspond with text citations and actual figures.  


Article Promotion Support  

Wiley Editing Services offers professional video, design, and writing services to create shareable video abstracts, infographics, conference posters, lay summaries, and research news stories for your research – so you can help your research get the attention it deserves. 


Author Name Change Policy  

In cases where authors wish to change their name following publication, Wiley will update and republish the paper and redeliver the updated metadata to indexing services. Our editorial and production teams will use discretion in recognizing that name changes may be of a sensitive and private nature for various reasons including (but not limited to) alignment with gender identity, or as a result of marriage, divorce, or religious conversion. Accordingly, to protect the author’s privacy, we will not publish a correction notice to the paper, and we will not notify co-authors of the change. Authors should contact the journal’s Editorial Office with their name change request. 


Correction to authorship  

In accordance with Wiley’s Best Practice Guidelines on Research Integrity and Publishing Ethics and the Committee on Publication Ethics’ guidance, Acta Physiologica will allow authors to correct authorship on a submitted, accepted, or published article if a valid reason exists to do so. All authors – including those to be added or removed – must agree to any proposed change. To request a change to the author list, please complete the Request for Changes to a Journal Article Author List Form and contact either the journal’s editorial or production office, depending on the status of the article. Authorship changes will not be considered without a fully completed Author Change form. [Correcting the authorship is different from changing an author’s name; the relevant policy for that can be found in Wiley’s Best Practice Guidelines under “Author name changes after publication.”] 



Resource Identification Initiative 

The journal supports the Resource Identification Initiative, which aims to promote research resource identification, discovery, and reuse. This initiative, led by the Neuroscience Information Framework and the Oregon Health & Science University Library, provides unique identifiers for antibodies, model organisms, cell lines, and tools including software and databases. These IDs, called Research Resource Identifiers (RRIDs), are machine-readable and can be used to search for all papers where a particular resource was used and to increase access to critical data to help researchers identify suitable reagents and tools. 

You will be asked to use RRIDs to cite the resources used in your research where applicable in the text, similar to a regular citation or Genbank Accession number. For antibodies, you should include in the citation the vendor, catalogue number, and RRID both in the text upon first mention in the Methods section. For software tools and databases, please provide the name of the resource followed by the resource website, if available, and the RRID. For model organisms, the RRID alone is sufficient. 

Additionally, you must include the RRIDs in the list of keywords associated with the manuscript. 


To Obtain Research Resource Identifiers (RRIDs): 

  1. Use the Resource Identification Portal, created by the Resource Identification Initiative Working Group. 
  2. Search for the research resource (please see the section titled “Search Features and Tips” for more information). 
  3. Click on the “Cite This” button to obtain the citation and insert the citation into the manuscript text. 


If there is a resource that is not found within the Resource Identification Portal, you are asked to register the resource with the appropriate resource authority. Information on how to do this is provided in the “Resource Citation Guidelines” section of the Portal. 

If any difficulties in obtaining identifiers arise, please contact [email protected] for assistance. 


Example Citations: 

Antibodies: "Wnt3 was localized using a rabbit polyclonal antibody C64F2 against Wnt3 (Cell Signaling Technology, Cat# 2721S, RRID: AB_2215411)" 

Model Organisms: "Experiments were conducted in c. elegans strain SP304 (RRID:CGC_SP304)" 

Cell lines: "Experiments were conducted in PC12 CLS cells (CLS Cat# 500311/p701_PC-12, RRID:CVCL_0481)" 

Tools, Software, and Databases: "Image analysis was conducted with CellProfiler Image Analysis Software, V2.0 (, RRID:nif-0000-00280)" 


Species Names 

Upon its first use in the title, abstract, and text, the common name of a species should be followed by the scientific name (genus, species, and authority) in parentheses. For well-known species, however, scientific names may be omitted from article titles. If no common name exists in English, only the scientific name should be used.  


Genetic Nomenclature 

Sequence variants should be described in the text and tables using both DNA and protein designations whenever appropriate. Sequence variant nomenclature must follow the current HGVS guidelines; see, where examples of acceptable nomenclature are provided. 


Sequence Data 

Nucleotide sequence data can be submitted in electronic form to any of the three major collaborative databases: DDBJ, EMBL, or GenBank. It is only necessary to submit to one database as data are exchanged between DDBJ, EMBL, and GenBank on a daily basis. The suggested wording for referring to accession-number information is: ‘These sequence data have been submitted to the DDBJ/EMBL/GenBank databases under accession number U12345’. Addresses are as follows: 

Proteins sequence data should be submitted to either of the following repositories:  


Structural Data 

For papers describing structural data, atomic coordinates and the associated experimental data should be deposited in the appropriate databank (see below). Please note that the data in databanks must be released, at the latest, upon publication of the article. We trust in the cooperation of our authors to ensure that atomic coordinates and experimental data are released on time.  

  • Organic and organometallic compounds: Crystallographic data should not be sent as Supporting Information, but should be deposited with the Cambridge Crystallographic Data Centre (CCDC) at 
  • Inorganic compounds: Fachinformationszentrum Karlsruhe (FIZ;
  • Proteins and nucleic acids: Protein Data Bank ( 
  • NMR spectroscopy data: BioMagResBank (  


Cover Image Submissions  

Acta Physiologica welcomes topical and interesting artwork submissions, in colour or black and white, for the journal cover. This is an optional service you can use to help increase article exposure and showcase your research. If you have such an image, please send it to [email protected]. Artwork submissions do not need to have been published previously. The figures should be supplied in the format detailed above and should have a suitable legend of no more than 100 words, including publication details.  

We reserve the right to redraw images prior to publication, subject to discussion. For more information, including artwork guidelines, pricing, and submission details, please visit the Journal Cover Image page 

Wiley Editing Services offers a professional cover image design service that creates eye-catching images, ready to be showcased on the journal cover. 


Additional Guidelines for Cover Pictures, Visual Abstracts, Frontispieces and Table of Contents Graphics 

  • Concepts illustrated in graphical material must clearly fit with the research discussed in the accompanying text. 
  • Images featuring depictions or representations of people must not contain any form of objectification, sexualization, stereotyping, or discrimination. We also ask authors to consider community diversity in images containing multiple depictions or representations of people. 
  • Inappropriate use, representation, or depiction of religious figures or imagery, and iconography should be avoided. 
  • Use of elements of mythology, legends, and folklore might be acceptable and will be decided on a case-by-case basis. However, these images must comply with the guidelines on human participants when they are present. 
  • Authors should consider any sensitivities when using images of objects that might have cultural significance or may be inappropriate in the context (for example, religious texts, historical events, and depictions of people). 
  • Legal requirements: 
    • All necessary copyright permission for the reproduction of the graphical elements used in visuals must be obtained prior to publication. 
    • Clearance must be obtained from identifiable people before using their image on the cover or the like and such clearance must specify that it will be used on the cover. Use within text does not require such clearance unless it discloses sensitive personal information such as medical information. In all situations involving disclosure of such personal info, specific permission must be obtained. And images of individuals should not be used in a false manner. 


Graphics that do not adhere to these guidelines will be recommended for revision or will not be accepted for publication. 


Embedded Rich Media 

This journal has the option for authors to embed rich media (i.e., video and audio) within their final article. These files should be submitted with the manuscript files online, using either the “Embedded Video” or “Embedded Audio” file designation. If the video/audio includes dialogue, a transcript should be included as a separate file. The combined manuscript files, including video, audio, tables, figures, and text must not exceed 350 MB. For full guidance on accepted file types and resolution please see here. 

Ensure each file is numbered (e.g., Video 1, Video 2, etc.) Legends for the rich media files should be placed at the end of the article. 

The content of the video should not display overt product advertising. Educational presentations are encouraged. 

Any narration should be in English, if possible. A typed transcript of any speech within the video/audio should be provided. An English translation of any non-English speech should be provided in the transcript.  

All embedded rich media will be subject to peer review. Editors reserve the right to request edits to rich media files as a condition of acceptance. Contributors are asked to be succinct, and the Editors reserve the right to require shorter video/audio duration. The video/audio should be high quality (both in content and visibility/audibility). The video/audio should make a specific point; particularly, it should demonstrate the features described in the text of the manuscript. 

Participant Consent: It is the responsibility of the corresponding author to seek informed consent from any identifiable participant in the rich media files. Masking a participant’s eyes, or excluded head and shoulders is not sufficient. Please ensure that a consent form ( is provided for each participant.  


Plain Language Summary 

The Plain Language Summary (PLS) should convey the same information as the Abstract but in a completely different language and tone. It should summarize your scientific study, its results, and their broader relevance without using jargon so that it is understandable by scientists from outside of your discipline, as well as science journalists and science educators. The PLS should be a single paragraph no more than 200 words long.