• Issue

    Fundamental & Clinical Pharmacology: Volume 35, Issue 1

    1-203
    February 2021
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Issue Information

  • Pages: 1-3
  • First Published: 06 February 2021

REVIEW ARTICLES

Progress on ocular siRNA gene-silencing therapy and drug delivery systems

Jinjin Jiang,  Xinru Zhang,  Yue Tang,  Shuhan Li,  Jing Chen, 
  • Pages: 4-24
  • First Published: 16 April 2020

Melatonin and morphine: potential beneficial effects of co-use

Karim Hemati,  Mohammad Hossein Pourhanifeh,  Ehsan Dehdashtian,  Iman Fatemi,  Saeed Mehrzadi,  Russel J. Reiter,  Azam Hosseinzadeh, 
  • Pages: 25-39
  • First Published: 15 May 2020

Ceftriaxone-associated biliary pseudolithiasis in children: do we know enough?

Laura Cuzzolin,  Anna Maria Oggiano,  Maria Grazia Clemente,  Cristian Locci,  Luca Antonucci,  Roberto Antonucci, 
  • Pages: 40-52
  • First Published: 03 June 2020

Impact of bariatric surgery on oral anticoagulants pharmacology, and consequences for clinical practice: a narrative review

Cyril Leven,  Clément Hoffmann,  Charles Roche,  Francis Couturaud,  Jérémie Thereaux,  Karine Lacut, 
  • Pages: 53-61
  • First Published: 03 July 2020

Pharmacological agents under investigation in the treatment of coronavirus disease 2019 and the importance of melatonin

Hakan Parlakpinar,  Seyhan Polat,  Haci Ahmet Acet, 
  • Pages: 62-75
  • First Published: 13 July 2020

Overview of French databases available for studying anticancer drugs in real-life setting

Emilie Casarotto,  Pernelle Noize,  Amandine Gouverneur,  Driss Berdaï,  Bernard Bégaud,  Laurie Levy-Bachelot,  Mathieu Molimard, 
  • Pages: 76-85
  • First Published: 02 August 2020

Oral drug delivery with nanoparticles into the gastrointestinal mucosa

Jiao Liu,  Ping Leng,  Yujun Liu, 
  • Pages: 86-96
  • First Published: 04 August 2020

ORIGINAL ARTICLES

Neuropsychopharmacology

Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats

Adel A. Gomaa,  Rania M. Makboul,  Mohamed A. El-Mokhtar,  Engy A. Abdel-Rahman,  Esraa A. Ahmed,  Mariam A. Nicola, 
  • Pages: 97-112
  • First Published: 30 June 2020
Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats Issue 1, 2021

Effect of donepezil on cognitive deficit in type 2 diabetes.

Neuropharmacology

The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences

Majid Motaghinejad,  Roya Mashayekh,  Manijeh Motevalian,  Sepideh Safari, 
  • Pages: 113-130
  • First Published: 24 June 2020

Sumatriptan reduces severity of status epilepticus induced by lithium–pilocarpine through nitrergic transmission and 5-HT1B/D receptors in rats: A pharmacological-based evidence

Faezeh Eslami,  Nastaran Rahimi,  Aysa Ostovaneh,  Mehdi Ghasemi,  Pegah Dejban,  Ata Abbasi,  Ahmad Reza Dehpour, 
  • Pages: 131-140
  • First Published: 13 July 2020

EDITORIAL

Targeting IL-10, ZO-1 gene expression and IL-6/STAT-3 trans-signalling by a combination of atorvastatin and mesalazine to enhance anti-inflammatory effects and attenuate progression of oxazolone-induced colitis

Davide Giuseppe Ribaldone,  Marta Vernero,  Gian Paolo Caviglia, 
  • Pages: 141-142
  • First Published: 08 December 2020

ORIGINAL ARTICLES

Inflammation, Immunopharmacology

Targeting IL-10, ZO-1 gene expression and IL-6/STAT-3 trans-signaling by a combination of atorvastatin and mesalazine to enhance anti-inflammatory effects and attenuates progression of oxazolone-induced colitis

Nageh Ahmed El-Mahdy,  Magda El-Sayed El-Sayad,  Aya Hassan El-Kadem,  Sally El-Sayed Abu-Risha, 
  • Pages: 143-155
  • First Published: 08 May 2020

Oncopharmacology

Abemaciclib sensitizes HPV-negative cervical cancer to chemotherapy via specifically suppressing CDK4/6-Rb-E2F and mTOR pathways

Yuan Liu,  Runsheng Zhao,  Shanshan Fang,  Quan Li,  Yiqiang Jin,  Bo Liu, 
  • Pages: 156-164
  • First Published: 23 May 2020

Targeting Wnt/β-catenin by anthelmintic drug niclosamide overcomes paclitaxel resistance in esophageal cancer

Wei Wei,  Hongfang Liu,  Jia Yuan,  Yang Yao, 
  • Pages: 165-173
  • First Published: 24 June 2020

Miscellaneous

Fentanyl inhibits acute myeloid leukemia differentiated cells and committed progenitors via opioid receptor-independent suppression of Ras and STAT5 pathways

Shuangbo Dai,  Xiaoqing Zhang,  Peng Zhang,  Xuesong Zheng,  Qiying Pang, 
  • Pages: 174-183
  • First Published: 21 June 2020

EDITORIAL

Cannabinoid hyperemesis syndrome in two French emergency departments: a prospective cohort

Nicolas Franchitto, 
  • Pages: 184-185
  • First Published: 09 January 2021

ORIGINAL ARTICLE

Cannabinoid hyperemesis syndrome in two French emergency departments: a prospective cohort

Julie Weiss,  Romain Torrents,  Baptiste Verhamme,  Antoine Roch,  Pierre Lazerges,  Maeva Jego,  Pierre Michelet,  Nicolas Simon, 
  • Pages: 186-191
  • First Published: 21 June 2020

EDITORIAL

Outcome of patients hospitalized for Covid-19 and exposure to angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers in France: Results of the ACECoV study

Joachim Alexandre,  Jean-Luc Cracowski, 
  • Pages: 192-193
  • First Published: 08 December 2020

ORIGINAL ARTICLE

Outcome of patients hospitalized for COVID-19 and exposure to angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers in France: results of the ACE-CoV study

Margaux Lafaurie,  Guillaume Martin-Blondel,  Pierre Delobel,  Sandrine Charpentier,  Agnès Sommet,  Guillaume Moulis, 
  • Pages: 194-203
  • First Published: 28 October 2020