Recently, Cen, Wang, Zhou et al. reported a crystal structure of a ternary complex of the non-heme iron endoperoxidase FtmOx1 (PDB entry 7ETK) and concluded that it provides evidence supporting the FtmOx1 catalysis CarC-like mechanistic model. However, this work did not accurately describe key mechanistic features and differences of the Carc-like and COX-like models, and their data do not support their conclusions.

The 2-oxoglutarate (2OG)-dependent non-heme enzyme FtmOx1 can catalyze the endoperoxidation of fumitremorgin B, producing verruculogen. The side product of deisoprenylation becomes the major product when the analogue 13-oxo-fumitremorgin B is used as the substrate. Fumitremorgin B and 13-oxo-fumitremorgin B show similar substrate-binding patterns with FtmOx1 but different enzymatic conversions.

In past decades, the orderly self-assembly of functionalized fluorophores has gained much attention. Such fluorophores can form nanoaggregates by self-assembly, which prolong their residence time in vivo, achieving high signal-to-background ratios and accurate bioimaging. In this review, we summarize progress and challenges of self-assembled fluorophores, focusing on their development history, self-assembly mechanism and biomedical applications.

We present a comprehensive overview of the recent synthetic advancements of covalent organic frameworks (COFs), with emphasis on the energy input required. These emerging strategies encompass microwave-assisted, sonochemical, mechanochemical, photochemical, plasma-promoted, electric field-induced, and electron beam-mediated synthesis. We also delve into the merits and limitations of these methods in comparison to the solvothermal approach.

Symmetry infers perfection and perennity, order, and harmony. Synthesizing perfluoropolyhedranes, a serious challenge, greatly enhances polyhedrane electron affinity, providing a unique opportunity for hosting an extra electron inside a molecular frame. The expectations for an easy entry to supramolecular chemistry hinted by such “cage” or “box” structures are, however, illusive.

The 40 years development of low-temperature electrolytes for rechargeable batteries has been reviewed. Critical insights are given from both underlying mechanistic and practical engineering aspects while we traverse the history on the rational design of low-temperature electrolyte systems.

Two improved methods for synthesis of poly(diphenylacetylene)s having functional groups have been developed. Molybdenum(V) catalysis with the MoCl₅-PhSnⁿBu₃ system provides linear poly(diphenylacetylene)s by migratory insertion polymerization while low-valent tungsten catalysis with the WCl₄-Ph₄Sn-PPh₃ system provides cyclic poly(diphenylacetylene)s by ring expansion polymerization.

A versatile molecular engineering strategy for regulating the solvation shell of metal cations has been reported, aiming to achieve a balanced H₂O activation behavior. By enriching the interface with aprotic organic molecules, the density of H₂O is decreased, and a second-sphere effect is delivered to stabilize the adsorbed H₂O molecule, leading to highly selective CO₂ electroreduction.

The use of various CN-functionalized conjugated molecules and Lewis acids has led to the synthesis of unprecedentedly strong organic p-dopants (LUMO level down to −5.93 eV) exhibiting excellent doping stability (over 40 h at 120 °C). Lewis pairing leads to the electron-withdrawing properties of the CN groups increasing almost twofold and the dopant size enlarging significantly.

Efficient charge transfer from organic ligands to metal halides in zero-dimensional organic metal halide hybrids [(C₆H₅)₄P]₂SbCl₅ is achieved through pressure modulation. It leads to high excitonic emission with near-unity photoluminescence quantum yield. In situ experimental and theoretical methods show that the pressure-induced electronic coupling between the lone-pair electrons of Sb³⁺ and the π electrons of benzene acts as an unexpected “bridge” for the charge transfer.

A general synthetic platform that could transform proteinogenic α-amino acids into a plethora of unprecedented tetrazole-decorated amino acid derivatives is developed via a silver-catalyzed intermolecular cycloaddition reaction with aryldiazonium salts.

A new, liquid-crystalline alignment medium for the measurement of residual dipolar couplings by NMR spectroscopy is presented. The medium is based on filamentous type 1 pili from E. coli and shown to withstand a wide range of challenging experimental conditions. Being compatible with biological macromolecules and small molecules alike, its high versatility suggests broad applicability in molecular structure determination by NMR.

Bacillus subtilis can be programmed to autonomously assemble recombinant silk peptides on its own membrane, and then release them as fibers into the extracellular milieu. The process, called secretion-catalyzed assembly, enables coupled synthesis, assembly, and processing of biomaterials by microbes.

The first catalytic asymmetric (4+2) and (4+3) cycloadditions of 2,3-indolyldimethanols enable the construction of enantioenriched indole-fused rings in high yields with excellent enantioselectivities. This approach led to the first enantioselective construction of challenging tetrahydroindolocarbazole scaffolds, which show promising anticancer activity. Theoretical calculations offer an in-depth understanding of this class of indolylmethanols.

Dual-active sites comprising Pt clusters and frustrated Lewis pairs (FLP) on porous CeO₂ nanorods provide an interface-independent pathway to boost the reverse water-gas shift reaction at low temperatures. The FLP sites enable strong adsorption of CO₂ for efficient activation, but weak adsorption of CO that suppresses CH₄ formation.

Oxyamination of gem-difluorodienes afforded 1,4-amino alcohol derivatives in excellent 1,4-regioselectivity and enantioselectivity. The reaction proceeded via rhodium(III) catalysis through an η³-allyl intermediate.

The potential of mechanical bonds in modulating the intrinsic characteristics of aerogels, such as porous microstructures and mechanical performances, has been demonstrated with mechanically interlocked aerogels. Such networks facilitate the development of smart materials with complex functionalities.

Unavoidable leaky protein expression limits in situ cell purification of synthetic mRNA switches. Harnessing the power of controlled self-assembly, we use synthetic mRNA switch to convey intracellular biomarker information into enzyme-controlled toxic assemblies only on the surface of undesired cells, promising high purity and high retention of target cells.

A facile and versatile method to synthesize a series of recyclable plastics has been developed. It involves the step polyaddition of diols, diacrylates, and COS and arises from the discovery of a new, modular, and efficient click reaction involving alcohol.

Using the complementary techniques of X-ray micro-computed tomography, scanning electron microscopy and energy dispersive X-ray spectroscopy, Pt ion migration was identified as an important factor to explain the decay in performance of anion-exchange membrane (AEM) fuel cells. The picture shows 3D reconstruction micro-CT images of the cross-section MEAs with Sustainion AEM and Pt/C cathode electrode after (a) 5 h and (b) 70 h of operation at 0.15 A/cm².

Reversible Si redox has been unlocked in Cl-based batteries through rational electrolyte dilution and anode passivation, which demonstrates excellent electrochemical performance and high practicability. It enables us to revisit the overlooked Cl-based batteries and to harness them for sustainable and high-performance energy storage.

We propose an efficient strategy to achieve simultaneously high photoluminescence quantum yield and large dissymmetry factor (g_lum) in chiral 0D hybrid metal halides by integrating achiral and chiral ligands. A pair of (R/S-MBA)₂(Gua)₄(In_0.99Sb_0.01Cl₆)₂ H₂O (MBA=α-methylbenzylammonium, Gua=guanidine) HMHs with near-unity PLQYs and large g_lum values (~0.01) are constructed.

A chiral metal-deficient Cu₅₇ hydride-rich nanocluster was prepared by a mixed-ligand strategy. Its total structure and electronic structure were established by combined experimental and DFT results. Its optical and catalytic hydrogenation properties were studied.

A tumor-targeted CRISPR/Cas delivery strategy was developed to switch on antitumor immunity via bioorthogonal reaction. Selectively labeling tumor sites and the activation of the cGAS-STING pathway was achieved first, turning “cold” tumors into “hot”. The targeted accumulation of the CRISPR/Cas system within tumors via click chemistry then further enhanced cancer immunotherapy, substantially boosting antitumor effectiveness.

A new mode of difluorocarbene transfer reaction that tames difluorocarbene to couple with two electrophiles via palladium catalysis has been developed. This reaction overcomes the intrinsic limitations of electrophilic difluorocarbene and allows difluoromethylation of various aryl bromides and aryl triflates. Experimental mechanistic studies revealed that a palladium(0/II) pathway is responsible for this reductive reaction.

Novel cyclodextrin-supported Co(OH)₂ cluster electrocatalysts were prepared through a mild and facile synthetic method, affording excellent 2 e⁻ ORR activity for efficient and selective H₂O₂ synthesis.

Olefin-linked covalent organic frameworks (COFs) with electronegative 1D channels are presented as a cationic highway membrane strategy for sustainable Li metal battery anodes. Introduction of triazine rings and fluorinated groups into the COF skeletons played a viable role in enhancing salt dissociation and guiding uniform Li⁺ flux within the channels. The resulting COF membrane exhibited reliable Li plating/stripping cyclability and stable capacity retention in the Li/LiFePO₄ full cell.

We have proposed the radical-triggered luminescence to monitor the radical behaviours during polymer degradation. It was disclosed that the pure polymers showed a single sigmoidal dynamic curve from ROO⋅ emissions, leading to the exponential proliferation for the degradation evolution. Alternatively, the degradation pathways of polymers were regulated into a double sigmoidal curve by anti-degradation LDHs.

The site-selective C−H functionalizations of 3- and 4-phenylpyridine biaryls at sterically disfavored ortho positions were realized by developing two new catalytic templates.

A robust chem-stamp approach consisting of two steps, one-carbon extension of aldehydes to alkenyl boronates and the rhodium-catalyzed reaction of these alkenyl boronates with 2,3-allenols, has been developed for the construction of key isoprene units in terpenoids. This approach enables the modular concise synthesis of terpenoids and the creation of artificial terpenoids with control over the number of isoprene units, the side chain, and two terminal groups.

Single-crystalline poly (Triazine Imide)/Li⁺Cl⁻ nanosheets with more exposed active sites and efficient charge transfer present a record apparent quantum efficiency of 25 % for photocatalytic overall water splitting.

Linked fragments for molecular glue development for the 14-3-3/ERα protein-protein interactions (PPIs) are described. Two classes of fragments were co-crystallized and subsequently linked, resulting in a noncovalent hybrid molecule that was further optimized, guided by 20 crystal structures, resulting in a selective 25-fold stabilization of the 14-3-3/ERα PPIs.

In situ peptide self-assembly into a nano proteolysis targeting chimeras (Nano-PROTACs) system was reported with “anti-hook effect” to realize dose-dependent and long-acting protein degradation in vitro and in vivo.

A fusion protein of Nano-luciferase and HaloTag was engineered to construct a DNAzyme sensor for metal ion detection in vivo, utilizing bioluminescent resonance energy transfer (BRET).

Reduction of a bulky magnesium(II) diamide with 5 % w/w K/KI under an N₂ atmosphere has given a complex between magnesium and doubly reduced dinitrogen, N₂²⁻. The reaction has been calculated to proceed via an anionic magnesium(I) radical, and the final product shown to act as a masked dimagnesium(I) diradical in reactions with CO, H₂ and C₂H₄.

Carbon dioxide and propene oxide ring opening copolymerization is a leading carbon dioxide utilization technology. Future catalyst development needs better understanding of how to maximize both activity and selectivity. Here, a series of catalysts show a correlation between both their activity and selectivity values with the cobalt reduction potential, providing a useful ‘predictive’ tool for catalyst performances.

A new strategy that could enable the polymerizations of thiyl radical propagation to be controlled by existing RDRP methods has been reported. The key to this strategy is the propagating thiyl radicals could undergo desulfurization with isocyanides to generate stabilized alkyl radicals, thereby allowing for controlling the polymerization via RAFT agents, leading to the formation of main-chain polymers with well-defined architectures.

A series of HOFs with unique pore structures have been designed by precise pore modulation engineering through the introduction of structure directing agents. One example is HOF-ZSTU-2 with a one-dimensional pearl-chain channel that balances size control, adsorption capacity, and functional sites for efficient storage and separation of propylene.

A nickel-catalyzed selective C(sp²)−F bond alkylation of the inexpensive industrial chemical HFO-1234yf with alkylzinc reagents has been developed. Preliminary mechanistic studies reveal that the less electron-rich pyridine-oxazoline or bipyridine-based ligands feature comparable or even higher rates of C−F bond oxidative addition than the electron-rich phosphine ligands in the presence of lithium bromide.

Like two color-changing chameleons coming face to face, integration of two distinct stimuli-responsive moieties within the same platform results in their synergistic behavior. Perturbation of the chameleons’ environment upon a different external stimulus breaks the synergy, promoting their orthogonal behavior, a concept highlighted for a novel hierarchical photo-thermo-responsive metal–organic framework.

We reported the on-demand development of phosphonium fluoropolymers as the electrostatic shielding interlayer to stabilize Li metal anodes, where the periodic arrangement of F/P units not only adaptively homogenized electric field distribution to induce dendrite-free Li deposition, but also restrained undesirable coating decomposition to provide persistent protection for long-term battery cycling.

Traditional sulfur conversion reactions suffer from severe shuttle effects as well as sluggish redox kinetics. Here, we achieved an endogenous facilitation mechanism for sulfur conversion which constructed a fast “internal cycle” of the promotors to promote the slow “external cycle” of sulfur conversions by coupling lithium polysulfides with functional molecules. By regulating the intermediates solubility and mediating the reaction kinetics, organophosphorus polysulfides as endogenous promotors can simultaneously eliminate the shuttle effect and improve the sulfur electrode process.

The co-assembly of the pyridine-based tricarboxamides 2–4 with tricarboxamide 1 is investigated. Whilst the formation of the supramolecular co-polymer poly-1-co-2 is not possible, co-polymers poly-1-co-3 and poly-1-co-4 are formed. The latter has been investigated by mass-balance model that revealed an alternating blocky microstructure.

Supramolecular soft actuators have been developed that are based on hydrogen-bond crosslinked liquid-crystal elastomers (LCEs). The LCEs can be manufactured in the form of fibers and 2D/3D objects that are capable of performing stable and reversible thermal actuation under mechanical stretch or melt extrusion, opening the way for the one-step and custom manufacturing of soft actuators.

Electrolytes based on polymers with intrinsic microporosity (PIMs) are proposed as ideal solid electrolytes for lithium batteries. Benefiting from rational material selection and structure design, solid-state Li−O₂ batteries deliver high discharge specific capacity (11307 mAh g⁻¹) and prolonged cycling life (247 cycles). The solid-state Li-metal batteries can operate steadily for over 100 cycles after a series of abuse tests (bending and twisting).

Proton co-insertion into tunnel materials is determined jointly by interface derivation and inner diffusion. At the electrode-electrolyte interface, hydrated Mg²⁺ has poor insertion kinetics and thus accumulates on the surface of VO₂(B) to hydrolyze, triggering the formation of Mg-rich SEI and production of protons. In the tunnels, co-inserted/lattice H₂O molecules block the Mg²⁺ diffusion while facilitate proton diffusion.

A coordination defect-induced strategy gives frustrated Lewis pair (FLP) sites in a polyoxometalate (POM) based metal–organic framework (MOF), where the Lewis acid (LA) sites are linker-defective metal nodes and the Lewis base (LB) sites are derived from surface oxygen atoms of the POM. This FLP catalyst achieved heterolytic dissociation of H₂ into highly active H^δ−, thus exhibiting excellent activity in acetylene hydrogenation.

Li-rich layer oxide (LRLO) cathodes with semi-metallic superionic layers are prepared via a simple one-step modification. The inner semi-metallic LiMn₂O₄-like structure (LMO), has spin-polarized conducting electrons that can bond with oxygen, preventing oxygen release. The outer fast-ion conductor Li_0.8Nb_0.96Ni_0.2O₃ (LNO) acts as a fast-ion conductor facilitating Li⁺ migration and alleviating metal dissolution.

Based on comprehensive comparison on mechanical properties between dually cross-linked network and individual covalent or supramolecular cross-linked network, we reveal that the dual cross-linking mode can combine the advantages of covalent cross-links and supramolecular cross-links, exhibiting not only quick deformation recovery, outstanding breaking stress and puncture resistance, but also excellent toughness and energy dissipation ability.

The balance between crystallinity and film-formation of metal–organic framework (MOF) membrane is demonstrated for the first time using a facile in situ modulation strategy. Through competitive complexation with a ligand, acetic acid systematically reduces the crystallinity and optimizes the film formation of the MOF membrane, influencing its gas separation properties.

To promote the spontaneous chemical reaction process of LaNiO_3−δ, the oxyanions were added into electrolytes to regulate the solid–liquid interface. The oxyanions adsorb onto the solid–liquid interface, disrupting the dynamic equilibrium between the adsorbed OH⁻ ions and the OH⁻ ions generated during surface reconstruction. It could be an effective way to accelerate surface reconstruction process.

A Pd-catalyzed divergent bissilylation of alkynoates using disilane reagent TMDQ (see TOC graphic) is presented. Reversed regio- and stereo-selectivity was obtained through addition of Lewis acids. MAD (methylaluminum bis(2,6-di-t-butyl-4-methylphenoxide) impacted electronically-favored migratory insertion through steric effect while the addition of BCF (tris(pentafluorophenyl)borane) allowed reductive elimination as the rate-determining step.

One/two-photon-excited long persistent luminescence (LPL) was obtained in an ESIPT-attributed Cd^II coordination polymer (LIFM-106) with wide temperature range (100–380 K) and color tunability. Comparative study manifests the rational ligand modification and J-aggregation in LIFM-106 enhances the competitiveness of monomer LPL to counter-balance the excimer emission.

Selective xylene synthesis from CO₂ hydrogenation was achieved by regulating the interaction between two active components of a composite catalyst through a toluene-containing coupling reaction. The relationship between ZnZrO and the zeolite involved in the promotion effect was explored with detailed characterization.

A novel bimetallic Ni−Cu electrode for the oxidation of 5-hydroxymethyl furfural (HMF) to 2,5-furandicarboxylic acid (FDCA) with an industrial-scale current density of up to 1000 mA cm⁻² has been successfully developed. Superior stability and activity of the prepared electrode enable the gram-scale production of FDCA with a very high overall yield, purity, and Faradaic efficiency.

A nuclearity-dependent enantiodivergent epoxide opening reaction has been developed based on a mononuclear (salen)Ti^III complex and its self-assembled oxygen-bridged dinuclear counterparts within the same stereogenic ligand scaffold. Mechanistic studies reveal that the nuclearity-distinct catalysts regulate the enthalpy and entropy controlling modes in the enantiodifferentiation process to achieve profound chirality inversion.

An unprecedented robust metal organic framework ZNU-9 with a new wly topology and featuring multiple anion functionalities and hierarchical porosity was reported for simultaneous efficient C₂H₂/CO₂ and C₂H₂/C₂H₄ separation with both high capacity and high selectivity.

Bimanes allow the synthesis of water-soluble single-chain nanoparticles (SCNPs) and enable the effective unfolding with mild visible light from a compact structure into a linear chain. The unfolding of the fluorescent nanoparticles is reversible and occurs in aqueous systems, making it promising for controlling and tracing the SCNPs in biological environments.

Several ATP-binding cassette (ABC) transporters possess asymmetric nucleotide-binding sites (NBSs). Here, we elucidated its functional relevance using concomitant NO−NO, Mn²⁺−NO, and Mn²⁺−Mn²⁺ distance measurements for the ABC exporter TmrAB in a time-resolved manner. Our results shows that ATP hydrolysis at the active consensus NBS accelerates the reverse transition, and the impaired degenerate NBS might regulate the overall kinetics of this process.

We developed a new strategy to enable light-driven nitrogen fixation in non-photosynthetic bacteria by integrating the novel conjugated oligoelectrolyte COE-IC into A. vinelandii. Upon excitation of light, COE-IC generates electron equivalents at the abiotic-biotic interface. These photoelectrons are then transferred to nitrogenase, which drives the reduction of dinitrogen to ammonia.

A regioselective formal Tsuji–Trost β-allylation of various carbonyl compounds with different allylic electrophiles is reported. Reactions proceed through initial silyl enol ether formation and subsequent cooperative photoredox/nickel catalysis.

An ionic gel interfacial layer is applied to improve the ionic transport of the hydrophobic conjugated polymers in organic electrochemical transistors (OECTs). With this approach, hydrophobic conjugated polymers could be used directly, while the types and ratios of gel matrix and ionic liquids in the ionic gels could be tuned to achieve optimal OECT properties for improved performance.

Poly (triazine imide) modified with Rh/Cr₂O₃ and CoO_x as H₂ and O₂ evolution cocatalysts, respectively, largely improves the charge separation efficiency and restrains the undesired backward reaction, achieving an apparent quantum efficiency of 20.2 % for photocatalytic overall water splitting.

A highly efficient iridium-catalyzed asymmetric C−H alkylation reaction is described. A series of structurally diverse indole-pyrrole and pyrrole-pyrrole N−N atropisomers were obtained in good yields (up to 98 %) with excellent enantioselectivity (up to 99 % ee). This reaction features perfect atom economy, wide substrate scope, and multifunctionalized products allowing diverse transformations.

Introduction of aryl rings in the backbone of polymer chains is one of the key strategies to improve the chain rigidity and hence the properties. In peptide chemistry the technique gave birth to a new class of molecular systems called arylopeptides. Here we discuss the synthesis of polyarylopeptides, peptide polymers with periodic aryl units, from amino acid-based monomers via topochemical azide-alkyne cycloaddition polymerization.

Peptide-tethered diacetylene monomers exhibit efficient topochemical photopolymerization and allow control over the chiroptical properties of the resulting chiral polydiacetylenes. Achiral and chiral gold nanoparticles were incorporated in the chiral polymers and the stereoselective plasmonic interactions investigated, with the ultimate goal of designing next-generation organic–inorganic hybrid materials with large chiroptic effects.

A bifunctional catalyst composed of hydrophobic FeNa@Si-c and HZSM-5 zeolite converts syngas to gasoline with high selectivity. The diffusion of water molecules through a hydrophilic catalyst is bidirectional, while the diffusion through a hydrophobic catalyst is unidirectional, thereby allowing control of syngas-to-gasoline side reactions related to water.

Single-atom modifications are typically accompanied by appreciable changes to the overall particle's structure. Herein, we demonstrate surface single-atom manipulation based on [Cu₅₈H₂₀PET₃₆(PPh₃)₄]²⁺ (Cu₅₈; PET: phenylethanethiolate; PPh₃: triphenylphosphine), leading to the isostructural analogue [Cu₅₇H₂₀PET₃₆(PPh₃)₄]⁺ (Cu₅₇). Remarkably, this single surface atom drastically alters the catalytic reactivity of the nanoclusters.

A homo-Mannich reaction of cyclopropanol with an iminium ion, generated by an asymmetric allylic dearomatization of indole, has been developed to construct a tricyclic hydrocarbazole core. This approach enables a collective asymmetric synthesis of ibophyllidine, Aspidosperma, Kopsia, and Melodinus alkaloids having either a five-, six-, or seven-membered E ring.

An unexpected chiral adaptive induction of an achiral CB[8]-based supramolecular organic framework (SOF) was explored, exhibiting the opposite CD and CPL spectra in the presence of L-TrpTrp and L-PhePhe, respectively. Furthermore, this SOF demonstrates the sequence-selective chiral induction for sequences-opposite Trp-/Phe-containing dipeptides, allowing for the discrimination and differentiation of these dipeptide sequences.

How would a chiral environment impact the dynamics of hydrogen atoms? Using rotational spectroscopy in combination with the solutions of a simple one-dimensional Schrödinger equation approach, we revealed the intriguing distinctions of hydrogen atom dynamics between homochiral and heterochiral dimers of trans-1,2-cyclohexanediol.

Quantitative assembly of bent amphiphiles with two ferrocene units leads to a ferrocene-based capsule in water. Besides redox-responsive disassembly/assembly properties, the new capsule displays unusual host-guest charge-transfer (CT) interactions upon encapsulation of electron-accepting molecules in the multi-ferrocene cavity. The CT interactions are facilely dissociated by a redox-triggered stimulus.

The long persistent luminescence (LPL) of 2D Cs₂CdCl₄ Ruddlesden-Popper phase perovskites based on the self-assembled 2D interlayer galleries structure is investigated. Through doping engineering, the LPL decay time is increased, the emission color is adjustable, and the thermal stability of PL is enhanced dramatically. Furthermore, we highlight the promising applications of Cs₂CdCl₄ perovskite systems in advanced anti-counterfeiting.

Bis(2-pyrimidyl) disulfide (Pym₂S₂) has proven to be a high rate cathode material for rechargeable lithium batteries. The superdelocalization of pyrimidyl groups is reducing the S−S bond dissociation energy, which depletes the intrinsic energy barrier of dissociated electron transfer. The lithium half cell achieves 2000 cycles at 5 C. In addition, the cell shows a capacity retention of 78.0 % after 500 cycles at 30 C.

The first report on electrochemical Au^I/Au^III catalysis for 1,2-difunctionalization of C−C multiple bonds has been presented. This external-oxidant-free approach utilizes the anodic oxidation of vinyl-Au^I to vinyl-Au^III complexes to achieve oxy-alkynylation of allenoates to access alkyne-substituted butenolides in an undivided cell.

The linear relationship between reduction potential differences (ΔE) and substituent constants (σ) of aryl difluoromethyl sulfones provides a powerful strategy to solve the dilemma of acidities and reduction potentials of difluoromethylating agents. The strategy enabled achieving enantioselective difluoromethylation-alkynylation reactions of olefins with difluoromethyl 4-chlorophenyl sulfone.

We reported dual-emissive iridium(III) complexes bearing a di(2-picolyl)-amine (DPA) unit, which exhibited green and red dual phosphorescence in aqueous solutions. The complexes exhibited static and dynamic phosphorescence quenching in response to copper(II) ions and oxygen, respectively, at different wavelengths, achieving colorimetric emission response in solutions and multichannel response in live cell imaging.

Ultrasound or ball milling of piezoelectric particles to control atom transfer radical polymerization (ATRP) requires high-energy and high-frequency mechanical stimuli. Tribochemically controlled ATRP (tribo-ATRP) using titanium oxide particles and CuBr₂/tris(2-pyridylmethyl)amine enables a contact-electrification catalysis (ca. 10 Hz) and gives access to a variety of polymers with predetermined molecular weights, low dispersity, and high chain-end fidelity.

Amide carbonyl group usually serves as the electrophile, which can react with various nucleophiles. The current work shows a process to achieve the umpolung reactivity of tertiary amide carbonyl group. By leveraging this strategy, tertiary amide can react with a wide range of electrophiles to produce complex amines.