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PPARs: A Double-Edged Sword in Cancer Therapy?
- First Published: 29 June 2009
Editorial
Open Access
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Peroxisome Proliferator-Activated Receptor δ: A Target with a Broad Therapeutic Potential for Drug Discovery
- First Published: 07 April 2009
Editorial
Open Access
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Development of Synthetic Modulators of PPARs: Current Challenges and Future Opportunities
- First Published: 23 March 2009
Review Article
Open Access
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PPARγ in Kidney Physiology and Pathophysiology
- First Published: 10 March 2009
Review Article
Open Access
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Combination Therapy of PPARγ Ligands and Inhibitors of Arachidonic Acid in Lung Cancer
- First Published: 04 March 2009
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors in Diabetic Nephropathy
- First Published: 04 March 2009
Review Article
Open Access
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Protective Actions of PPAR-γ Activation in Renal Endothelium
- First Published: 26 February 2009
Review Article
Open Access
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The Role of NF-κB in PPARα-Mediated Hepatocarcinogenesis
- First Published: 29 January 2009
Review Article
Open Access
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Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARα + γ Agonists
- First Published: 28 January 2009
Review Article
Open Access
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The Role of PPARγ Receptors and Leukotriene B4 Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer
- First Published: 27 January 2009
Research Article
Open Access
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Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells
- First Published: 24 December 2008
Review Article
Open Access
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PPARs Mediate Lipid Signaling in Inflammation and Cancer
- First Published: 21 December 2008
Review Article
Open Access
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Clinical Use of PPARγ Ligands in Cancer
- First Published: 18 December 2008
Research Article
Open Access
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Regulation of Peroxisome Proliferator-Activated Receptors by E6-Associated Protein
- First Published: 18 December 2008
Clinical Study
Open Access
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Antidiabetic Rosiglitazone Reduces Soluble Intercellular Adhesion Molecule-1 Level in Type 2 Diabetic Patients with Coronary Artery Disease
- First Published: 18 December 2008
Review Article
Open Access
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The Potential Applications of Peroxisome Proliferator-Activated Receptor δ Ligands in Assisted Reproductive Technology
- First Published: 16 December 2008
Review Article
Open Access
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PPARγ, PTEN, and the Fight against Cancer
- First Published: 14 December 2008
Research Article
Open Access
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Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors
- First Published: 11 December 2008
Review Article
Open Access
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The Role of PPARs in the Endothelium: Implications for Cancer Therapy
- First Published: 24 November 2008
Review Article
Open Access
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PPARγ and Agonists against Cancer: Rational Design of Complementation Treatments
- First Published: 18 November 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptor β/δ in the Brain: Facts and Hypothesis
- First Published: 09 November 2008
Review Article
Open Access
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PPARα/γ-Independent Effects of PPARα/γ Ligands on Cysteinyl Leukotriene Production in Mast Cells
- First Published: 09 November 2008
Review Article
Open Access
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Potential Therapeutic Use of PPARγ-Programed Human Monocyte-Derived Dendritic Cells in Cancer Vaccination Therapy
- First Published: 05 November 2008
Review Article
Open Access
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PPARδ Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities
- First Published: 29 October 2008
Review Article
Open Access
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The Role of the PAX8/PPARγ Fusion Oncogene in Thyroid Cancer
- First Published: 29 October 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle
- First Published: 22 September 2008
Review Article
Open Access
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Regulation of Cell Proliferation and Differentiation by PPARβ/δ
- First Published: 16 September 2008
Research Article
Open Access
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[Retracted] Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARγ Dependent and Independent Mechanisms
- First Published: 15 September 2008
Review Article
Open Access
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PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion
- First Published: 14 September 2008
Research Article
Open Access
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Cross-Species Differential Plasma Protein Binding of MBX-102/JNJ39659100: A Novel PPAR-γ Agonist
- First Published: 14 September 2008
Review Article
Open Access
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To Live or to Die: Prosurvival Activity of PPARγ in Cancers
- First Published: 08 September 2008
Review Article
Open Access
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TZDs and Bone: A Review of the Recent Clinical Evidence
- First Published: 08 September 2008
Review Article
Open Access
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Renal and Vascular Mechanisms of Thiazolidinedione-Induced Fluid Retention
- First Published: 07 September 2008
Review Article
Open Access
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PPARγ: The Portrait of a Target Ally to Cancer Chemopreventive Agents
- First Published: 03 September 2008
Review Article
Open Access
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CXCR4 in Cancer and Its Regulation by PPARγ
- First Published: 02 September 2008
Review Article
Open Access
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Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types
- First Published: 02 September 2008
Review Article
Open Access
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The Role of PPARγ in the Cyclooxygenase Pathway in Lung Cancer
- First Published: 27 August 2008
Review Article
Open Access
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Omega-3 Fatty Acids and PPARγ in Cancer
- First Published: 27 August 2008
Review Article
Open Access
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The Development of INT131 as a Selective PPARγ Modulator: Approach to a Safer Insulin Sensitizer
- First Published: 26 August 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors in the Modulation of the Immune/Inflammatory Response in Atherosclerosis
- First Published: 21 August 2008
Review Article
Open Access
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Pioglitazone versus Rosiglitazone: Effects on Lipids, Lipoproteins, and Apolipoproteins in Head-to-Head Randomized Clinical Studies
- First Published: 21 August 2008
Research Article
Open Access
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Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor γ with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development
- First Published: 21 August 2008
Review Article
Open Access
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Chondrosarcoma and Peroxisome Proliferator-Activated Receptor
- First Published: 17 August 2008
Review Article
Open Access
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PPARα Ligands as Antitumorigenic and Antiangiogenic Agents
- First Published: 14 August 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors (PPARs) as Potential Inducers of Antineoplastic Effects in CNS Tumors
- First Published: 14 August 2008
Review Article
Open Access
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Activated PPARγ Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells
- First Published: 13 August 2008
Research Article
Open Access
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Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling
- First Published: 28 July 2008
Review Article
Open Access
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Role of Peroxisome Proliferator-Activated Receptor Alpha in the Control of Cyclooxygenase 2 and Vascular Endothelial Growth Factor: Involvement in Tumor Growth
- First Published: 28 July 2008
Review Article
Open Access
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PPAR Regulation of Inflammatory Signaling in CNS Diseases
- First Published: 28 July 2008
Review Article
Open Access
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PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes
- First Published: 15 July 2008
Review Article
Open Access
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Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?
- First Published: 14 July 2008
Review Article
Open Access
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PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis
- First Published: 14 July 2008
Review Article
Open Access
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Pathophysiological Roles of PPARγ in Gastrointestinal Epithelial Cells
- First Published: 06 July 2008
Review Article
Open Access
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The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products
- First Published: 06 July 2008
Review Article
Open Access
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Do PPARγ Ligands Suppress the Growth of Cholangiocarcinoma or the Cholangiohepatitis Induced by the Tumor?
- First Published: 06 July 2008
Review Article
Open Access
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A Novel Mechanism of PPARγ Regulation of TGFβ1: Implication in Cancer Biology
- First Published: 03 July 2008
Review Article
Open Access
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The Role of PPAR-γ and Its Interaction with COX-2 in Pancreatic Cancer
- First Published: 02 July 2008
Research Article
Open Access
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The PPAR-γ Agonist 15-Deoxy-Δ12,14-Prostaglandin J2 Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer′s Disease
- First Published: 02 July 2008
Review Article
Open Access
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PPAR-γ: Therapeutic Potential for Multiple Sclerosis
- First Published: 29 June 2008
Research Article
Open Access
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Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
- First Published: 19 June 2008
Review Article
Open Access
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Peroxisome Proliferators-Activated Receptor (PPAR) Modulators and Metabolic Disorders
- First Published: 15 June 2008
Review Article
Open Access
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Structural Development Studies of Subtype-Selective Ligands for Peroxisome Proliferator-Activated Receptors (PPARs) Based on the 3,4-Disubstituted Phenylpropanoic Acid Scaffold as a Versatile Template
- First Published: 15 June 2008
Review Article
Open Access
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[Retracted] A Role for PPAR γ in the Regulation of Cytokines in Immune Cells and Cancer
- First Published: 12 June 2008
Review Article
Open Access
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PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
- First Published: 12 June 2008
Review Article
Open Access
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Multiple Interactions between Peroxisome Proliferators-Activated Receptors and the Ubiquitin-Proteasome System and Implications for Cancer Pathogenesis
- First Published: 08 June 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors and Progression of Colorectal Cancer
- First Published: 05 June 2008
Review Article
Open Access
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Screening for PPAR Responsive Regulatory Modules in Cancer
- First Published: 05 June 2008
Review Article
Open Access
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The Roles of Dietary PPARγ Ligands for Metastasis in Colorectal Cancer
- First Published: 05 June 2008
Review Article
Open Access
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NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
- First Published: 29 May 2008
Review Article
Open Access
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Synergistic Effects of PPARγ Ligands and Retinoids in Cancer Treatment
- First Published: 28 May 2008
Review Article
Open Access
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PPARγ Inhibitors as Novel Tubulin-Targeting Agents
- First Published: 26 May 2008
Review Article
Open Access
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Role of Peroxisome Proliferator-Activated Receptor Gamma and Its Ligands in the Treatment of Hematological Malignancies
- First Published: 26 May 2008
Review Article
Open Access
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Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-γ Ligands in Lung Cancer
- First Published: 26 May 2008
Review Article
Open Access
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PPARγ Agonists: Potential as Therapeutics for Neovascular Retinopathies
- First Published: 26 May 2008
Review Article
Open Access
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The Role of PPARγ in Hepatocellular Carcinoma
- First Published: 26 May 2008
Review Article
Open Access
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PPAR-γ Thiazolidinedione Agonists and Immunotherapy in the Treatment of Brain Tumors
- First Published: 22 May 2008
Review Article
Open Access
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Anticancer Properties of PPARα-Effects on Cellular Metabolism and Inflammation
- First Published: 20 May 2008
Review Article
Open Access
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A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
- First Published: 15 May 2008
Review Article
Open Access
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The Critical Role of PPARγ in Human Malignant Melanoma
- First Published: 11 May 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptor-γ in Amyotrophic Lateral Sclerosis and Huntington′s Disease
- First Published: 24 April 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptor- γ Ligands: Potential Pharmacological Agents for Targeting the Angiogenesis Signaling Cascade in Cancer
- First Published: 23 April 2008
Review Article
Open Access
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Regulation of Glial Cell Functions by PPAR-γ Natural and Synthetic Agonists
- First Published: 22 April 2008
Review Article
Open Access
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Therapeutic Potential of PPARγ Activation in Stroke
- First Published: 13 April 2008
Review Article
Open Access
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PPAR-α Ligands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration
- First Published: 06 April 2008
Review Article
Open Access
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PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice
- First Published: 06 April 2008
Editorial
Open Access
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PPARs and RXRs in Male and Female Fertility and Reproduction
- First Published: 06 April 2008
Editorial
Open Access
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PPARs/RXRs in Cardiovascular Physiology and Disease
- First Published: 31 March 2008
Review Article
Open Access
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Potential Therapeutic Targets for PPARγ after Spinal Cord Injury
- First Published: 27 March 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors: “Key” Regulators of Neuroinflammation after Traumatic Brain Injury
- First Published: 27 March 2008
Review Article
Open Access
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PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease
- First Published: 24 March 2008
Review Article
Open Access
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Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARγ Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J2
- First Published: 16 March 2008
Review Article
Open Access
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A Role for PPARβ/δ in Ocular Angiogenesis
- First Published: 11 March 2008
Review Article
Open Access
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PPAR-γ, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
- First Published: 11 March 2008
Review Article
Open Access
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Regulation of Lymphocyte Function by PPARγ: Relevance to Thyroid Eye Disease-Related Inflammation
- First Published: 02 March 2008
Review Article
Open Access
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The Role of Peroxisome Proliferator-Activated Receptors in the Development and Physiology of Gametes and Preimplantation Embryos
- First Published: 28 February 2008
Clinical study
Open Access
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Peroxisome Proliferator-Activated Receptor-γ Is a Potent Target for Prevention and Treatment in Human Prostate and Testicular Cancer
- First Published: 19 February 2008
Research Article
Open Access
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Cryptochrome and Period Proteins Are Regulated by the CLOCK/BMAL1 Gene: Crosstalk between the PPARs/RXRα-Regulated and CLOCK/BMAL1-Regulated Systems
- First Published: 19 February 2008
Review Article
Open Access
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Should We Use PPAR Agonists to Reduce Cardiovascular Risk?
- First Published: 28 January 2008
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptor and Age-Related Macular Degeneration
- First Published: 27 January 2008
Review Article
Open Access
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Role of Peoxisome Proliferator Activator Receptor γ on Blood Retinal Barrier Breakdown
- First Published: 27 January 2008
Review Article
Open Access
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Placental Implications of Peroxisome Proliferator-Activated Receptors in Gestation and Parturition
- First Published: 20 January 2008
Research Article
Open Access
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Cardiac PPARα Protein Expression is Constant as Alternate Nuclear Receptors and PGC-1 Coordinately Increase During the Postnatal Metabolic Transition
- First Published: 17 January 2008
Review Article
Open Access
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The Roles of PPARs in the Fetal Origins of Metabolic Health and Disease
- First Published: 15 January 2008
Review Article
Open Access
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PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility
- First Published: 03 January 2008
Review Article
Open Access
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PPAR Agonists and Cardiovascular Disease in Diabetes
- First Published: 02 January 2008
Review Article
Open Access
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Hexarelin Signaling to PPARγ in Metabolic Diseases
- First Published: 02 January 2008
Review Article
Open Access
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PPAR Action in Human Placental Development and Pregnancy and Its Complications
- First Published: 30 December 2007
Review Article
Open Access
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The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects
- First Published: 24 December 2007
Review Article
Open Access
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Transcriptional Control of Vascular Smooth Muscle Cell Proliferation by Peroxisome Proliferator-Activated Receptor-γ: Therapeutic Implications for Cardiovascular Diseases
- First Published: 06 December 2007
Review Article
Open Access
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Peroxisome Proliferator-Activated Receptors as Mediators of Phthalate-Induced Effects in the Male and Female Reproductive Tract: Epidemiological and Experimental Evidence
- First Published: 06 December 2007
Research Article
Open Access
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Genetic Polymorphisms of Peroxisome Proliferator-Activated Receptors and the Risk of Cardiovascular Morbidity and Mortality in a Community-Based Cohort in Washington County, Maryland
- First Published: 04 December 2007
Review Article
Open Access
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The PPARα-PGC-1α Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium
- First Published: 22 November 2007
Review Article
Open Access
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PPAR Signaling in Placental Development and Function
- First Published: 21 November 2007
Review Article
Open Access
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Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism
- First Published: 20 November 2007
Review Article
Open Access
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Role of the Peroxisome Proliferator-Activated Receptors, Adenosine Monophosphate-Activated Kinase, and Adiponectin in the Ovary
- First Published: 23 August 2007