• Issue
    2020
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Research Article
Open Access

Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway

Yujing Xia,  Jingjing Li,  Kan Chen,  Jiao Feng,  Chuanyong Guo, 
  • First Published: 31 December 2020
Research Article
Open Access

Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Facilitates Cell Proliferation in Human Cholesteatoma Keratinocytes

Chen Zhang,  Yang-Wenyi Liu,  Zhangcai Chi,  Bing Chen, 
  • First Published: 28 December 2020
Research Article
Open Access

MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression

Xianjin Du,  Miao Wu,  Dan Tian,  Jianlin Zhou,  Lu Wang,  Liying Zhan, 
  • First Published: 22 December 2020
Research Article
Open Access

PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB

Wanshun Wen,  Jinlin Wang,  Biyu Zhang,  Jun Wang, 
  • First Published: 14 December 2020
Review Article
Open Access

Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction

Olga I. Rudko,  Artemii V. Tretiakov,  Elena A. Naumova,  Eugene A. Klimov, 
  • First Published: 30 November 2020
Research Article
Open Access

Nonclassical Axis of the Renin-Angiotensin System and Neprilysin: Key Mediators That Underlie the Cardioprotective Effect of PPAR-Alpha Activation during Myocardial Ischemia in a Metabolic Syndrome Model

María Sánchez-Aguilar,  Luz Ibarra-Lara,  Leonardo del Valle-Mondragón,  Elizabeth Soria-Castro,  Juan Carlos Torres-Narváez,  Elizabeth Carreón-Torres,  Alicia Sánchez-Mendoza,  María Esther Rubio-Ruíz, 
  • First Published: 28 November 2020
Research Article
Open Access

Nitric Oxide Mediates Inflammation in Type II Diabetes Mellitus through the PPARγ/eNOS Signaling Pathway

Hua Guo,  Qinglan Zhang,  Haipo Yuan,  Lin Zhou,  Fang-fang Li,  Sheng-Ming Wang,  Gang Shi,  Maojuan Wang, 
  • First Published: 27 November 2020
Research Article
Open Access

The Model of PPARγ-Downregulated Signaling in Psoriasis

Vladimir Sobolev,  Anastasia Nesterova,  Anna Soboleva,  Evgenia Dvoriankova,  Anastas Piruzyan,  Dzerassa Mildzikhova,  Irina Korsunskaya,  Oxana Svitich, 
  • First Published: 09 October 2020
Research Article
Open Access

The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer

Runzhi Huang,  Jiaqi Zhang,  Mingxiao Li,  Penghui Yan,  Huabin Yin,  Suna Zhai,  Xiaolong Zhu,  Peng Hu,  Jiaxin Zhang,  Ling Huang,  Man Li,  Zehui Sun,  Tong Meng,  Daoke Yang,  Zongqiang Huang, 
  • First Published: 22 September 2020
Research Article
Open Access

A New Prognostic Risk Model Based on PPAR Pathway-Related Genes in Kidney Renal Clear Cell Carcinoma

Yingkun Xu,  Xiunan Li,  Yuqing Han,  Zilong Wang,  Chenglin Han,  Ningke Ruan,  Jianyi Li,  Xiao Yu,  Qinghua Xia,  Guangzhen Wu, 
  • First Published: 22 September 2020
Research Article
Open Access

Diet Modifies Pioglitazone’s Influence on Hepatic PPARγ-Regulated Mitochondrial Gene Expression

Sakil Kulkarni,  Jiansheng Huang,  Eric Tycksen,  Paul F. Cliften,  David A. Rudnick, 
  • First Published: 10 September 2020
Retraction
Open Access

Retracted: Rosiglitazone Suppresses the Growth and Invasiveness of SGC-7901 Gastric Cancer Cells and Angiogenesis In Vitro via PPARγ Dependent and Independent Mechanisms

PPAR Research , 
  • First Published: 01 September 2020

Review Article
Open Access

The Emerging Role of PPAR Beta/Delta in Tumor Angiogenesis

Siyue Du,  Nicole Wagner,  Kay-Dietrich Wagner, 
  • First Published: 13 August 2020
Research Article
Open Access

PPARD May Play a Protective Role against the Development of Schizophrenia

Xinrong Li,  Sha Liu,  Karan Kapoor,  Yong Xu, 
  • First Published: 07 August 2020
Review Article
Open Access

The PPAR Ω Pocket: Renewed Opportunities for Drug Development

Åsmund Kaupang,  Trond Vidar Hansen, 
  • First Published: 01 July 2020
Research Article
Open Access

Redox Regulation of PPARγ in Polarized Macrophages

Verena Trümper,  Ilka Wittig,  Juliana Heidler,  Florian Richter,  Bernhard Brüne,  Andreas von Knethen, 
  • First Published: 01 July 2020
Research Article
Open Access

Integrating Literature-Based Knowledge Database and Expression Data to Explore Molecular Pathways Connecting PPARG and Myocardial Infarction

Rongyuan Cao,  Yan Dong,  Kamil Can Kural, 
  • First Published: 01 June 2020
Research Article
Open Access

PPARG Could Work as a Valid Therapeutic Strategy for the Treatment of Lung Squamous Cell Carcinoma

Shunbin Shi,  Guiping Yu,  Bin Huang,  Yedong Mi,  Yan Kang,  Julia Pia Simon, 
  • First Published: 01 June 2020
Research Article
Open Access

Loss of Hepatocyte-Specific PPARγ Expression Ameliorates Early Events of Steatohepatitis in Mice Fed the Methionine and Choline-Deficient Diet

Jose Cordoba-Chacon, 
  • First Published: 01 May 2020
Research Article
Open Access

PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients

Ya. O. Yemchenko,  V. I. Shynkevych,  K. Ye Ishcheikin,  I. P. Kaidashev, 
  • First Published: 01 May 2020
Research Article
Open Access

PPARG Drives Molecular Networks as an Inhibitor for the Pathologic Development and Progression of Lung Adenocarcinoma

Min Zhao,  Xiaoyang Li,  Yunxiang Zhang,  Hongming Zhu,  Zhaoqing Han,  Yan Kang, 
  • First Published: 26 April 2020
Clinical Study
Open Access

Assessment of Changes in Concentration of Total Antioxidant Status, Acute-Phase Protein, and Prolactin in Patients with Osteoarthritis Subjected to a Complex Spa Treatment with Radon Water: Preliminary Results

Jadwiga Kuciel-Lewandowska,  Michał Kasperczak,  Lilla Pawlik-Sobecka,  Małgorzata Paprocka-Borowicz,  Jan Gnus, 
  • First Published: 23 April 2020
Research Article
Open Access

Pparg may Promote Chemosensitivity of Hypopharyngeal Squamous Cell Carcinoma

Meng Lian,  Jiaming Chen,  Xixi Shen,  Lizhen Hou,  Jugao Fang, 
  • First Published: 22 April 2020
Research Article
Open Access

Comparative Study of PPARγ Targets in Human Extravillous and Villous Cytotrophoblasts

Fulin Liu,  Christine Rouault,  Mickael Guesnon,  Wencan Zhu,  Karine Clément,  Séverine A. Degrelle,  Thierry Fournier, 
  • First Published: 01 April 2020
Research Article
Open Access

To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations

Holli-Joi Sullivan,  Xiaoyan Wang,  Shaina Nogle,  Siyan Liao,  Chun Wu, 
  • First Published: 01 April 2020
Research Article
Open Access

Adenosine Receptor A1-A2a Heteromers Regulate EAAT2 Expression and Glutamate Uptake via YY1-Induced Repression of PPARγ Transcription

Xianhua Hou,  Yuan Li,  Yuanyuan Huang,  Huan Zhao,  Li Gui, 
  • First Published: 06 March 2020
Review Article
Open Access

Association of Peroxisome Proliferator-Activated Receptors (PPARs) with Diabetic Retinopathy in Human and Animal Models: Analysis of the Literature and Genome Browsers

Špela Tajnšek,  Danijel Petrovič,  Mojca Globočnik Petrovič,  Tanja Kunej, 
  • First Published: 03 March 2020
Research Article
Open Access

Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ

Yong-Jik Lee,  Hyun Soo Kim,  Hong Seog Seo,  Jin Oh Na,  You-Na Jang,  Yoon-Mi Han,  Hyun-Min Kim, 
  • First Published: 01 February 2020
Review Article
Open Access

Peroxisome Proliferator-Activated Receptors as a Therapeutic Target in Asthma

Oxana Yu. Kytikova,  Juliy M. Perelman,  Tatyana P. Novgorodtseva,  Yulia K. Denisenko,  Viktor P. Kolosov,  Marina V. Antonyuk,  Tatyana A. Gvozdenko, 
  • First Published: 14 January 2020
Review Article
Open Access

PPARs and the Development of Type 1 Diabetes

Laurits J. Holm,  Mia Øgaard Mønsted,  Martin Haupt-Jorgensen,  Karsten Buschard, 
  • First Published: 09 January 2020