• Issue
    2016
Previous Issue|Next Issue
Export Citation(s)
Research Article
Open Access

The Protective Roles of ROS-Mediated Mitophagy on 125I Seeds Radiation Induced Cell Death in HCT116 Cells

Lelin Hu,  Hao Wang,  Li Huang,  Yong Zhao,  Junjie Wang, 
  • First Published: 29 December 2016
Research Article
Open Access

Regular and Moderate Exercise Counteracts the Decline of Antioxidant Protection but Not Methylglyoxal-Dependent Glycative Burden in the Ovary of Reproductively Aging Mice

S. Falone,  S. Jr Santini,  V. Cordone,  M. Grannonico,  M. Cacchio,  G. Di Emidio,  C. Tatone,  F. Amicarelli, 
  • First Published: 28 December 2016
Review Article
Open Access

Alternative Interventions to Prevent Oxidative Damage following Ischemia/Reperfusion

Simón Quetzalcoatl Rodríguez-Lara,  Ernesto German Cardona-Muñoz,  Ernesto Javier Ramírez-Lizardo,  Sylvia Elena Totsuka-Sutto,  Araceli Castillo-Romero,  Teresa Arcelia García-Cobián,  Leonel García-Benavides, 
  • First Published: 28 December 2016
Review Article
Open Access

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

Shanmugam Manoharan,  Gilles J. Guillemin,  Rajagopal Selladurai Abiramasundari,  Musthafa Mohamed Essa,  Mohammed Akbar,  Mohammed D. Akbar, 
  • First Published: 27 December 2016
Research Article
Open Access

Proteomics-Based Identification of the Molecular Signatures of Liver Tissues from Aged Rats following Eight Weeks of Medium-Intensity Exercise

Fanghui Li,  Tao Li,  Yanying Liu, 
  • First Published: 27 December 2016
Research Article
Open Access

Conservation of the Nrf2-Mediated Gene Regulation of Proteasome Subunits and Glucose Metabolism in Zebrafish

Vu Thanh Nguyen,  Yuji Fuse,  Junya Tamaoki,  Shin-ichi Akiyama,  Masafumi Muratani,  Yutaka Tamaru,  Makoto Kobayashi, 
  • First Published: 27 December 2016
Review Article
Open Access

The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease

Adam Jerzy Białas,  Przemysław Sitarek,  Joanna Miłkowska-Dymanowska,  Wojciech Jerzy Piotrowski,  Paweł Górski, 
  • First Published: 26 December 2016
Research Article
Open Access

Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells

Yi Zou,  Jun Wang,  Jian Peng,  Hongkui Wei, 
  • First Published: 26 December 2016
Research Article
Open Access

Nephroprotective Effects of N-Acetylcysteine Amide against Contrast-Induced Nephropathy through Upregulating Thioredoxin-1, Inhibiting ASK1/p38MAPK Pathway, and Suppressing Oxidative Stress and Apoptosis in Rats

Xuezhong Gong,  Yiru Duan,  Junli Zheng,  Yiquan Wang,  Guohua Wang,  Svante Norgren,  Tom K. Hei, 
  • First Published: 26 December 2016
Research Article
Open Access

Reversal of Trimethyltin-Induced Learning and Memory Deficits by 3,5-Dicaffeoylquinic Acid

Jin Yong Kang,  Seon Kyeong Park,  Tian Jiao Guo,  Jeong Su Ha,  Du Sang Lee,  Jong Min Kim,  Uk Lee,  Dae Ok Kim,  Ho Jin Heo, 
  • First Published: 25 December 2016
Research Article
Open Access

Phenolic Composition and Antioxidant and Antiproliferative Activities of the Extracts of Twelve Common Bean (Phaseolus vulgaris L.) Endemic Ecotypes of Southern Italy before and after Cooking

Maria Neve Ombra,  Antonio d’Acierno,  Filomena Nazzaro,  Riccardo Riccardi,  Patrizia Spigno,  Massimo Zaccardelli,  Catello Pane,  Mena Maione,  Florinda Fratianni, 
  • First Published: 25 December 2016
Research Article
Open Access

Demethoxycurcumin Preserves Renovascular Function by Downregulating COX-2 Expression in Hypertension

Yingjuan Li,  Danyang Tian,  Chunhua Zhu,  Liqun Ren, 
  • First Published: 25 December 2016
Editorial
Open Access

Redox-Activated Signal Transduction Pathways Mediating Cellular Functions in Inflammation, Differentiation, Degeneration, Transformation, and Death

Tetsuro Kamiya,  Michael Courtney,  Mikko O. Laukkanen, 
  • First Published: 22 December 2016
Research Article
Open Access

CD36/Sirtuin 1 Axis Impairment Contributes to Hepatic Steatosis in ACE2-Deficient Mice

Valéria Nunes-Souza,  Natalia Alenina,  Fatimunnisa Qadri,  Josef M. Penninger,  Robson Augusto S. Santos,  Michael Bader,  Luiza A. Rabelo, 
  • First Published: 22 December 2016
Research Article
Open Access

Ginkgo Biloba Ameliorates Subfertility Induced by Testicular Ischemia/Reperfusion Injury in Adult Wistar Rats: A Possible New Mitochondrial Mechanism

Asmaa Ibrahim Ahmed,  Noha N. Lasheen,  Khaled Mohamed El-Zawahry, 
  • First Published: 22 December 2016
Review Article
Open Access

Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury

Ravirajsinh N. Jadeja,  Kapil K. Upadhyay,  Ranjitsinh V. Devkar,  Sandeep Khurana, 
  • First Published: 22 December 2016
Research Article
Open Access

The Peroxidation of Leukocytes Index Ratio Reveals the Prooxidant Effect of Green Tea Extract

Ilaria Peluso,  Husseen Manafikhi,  Anna Raguzzini,  Yaroslava Longhitano,  Raffaella Reggi,  Christian Zanza,  Maura Palmery, 
  • First Published: 22 December 2016
Research Article
Open Access

Change in Free Radical and Antioxidant Enzyme Levels in the Patients Undergoing Open Heart Surgery with Cardiopulmonary Bypass

Fevzi Sarper Türker,  Ayşe Doğan,  Gonca Ozan,  Kurtuluş Kıbar,  Mine Erışır, 
  • First Published: 22 December 2016
Review Article
Open Access

Nitric Oxide: Exploring the Contextual Link with Alzheimer’s Disease

Nicholas Asiimwe,  Seung Geun Yeo,  Min-Sik Kim,  Junyang Jung,  Na Young Jeong, 
  • First Published: 21 December 2016
Editorial
Open Access

Plant-Derived Antioxidants in Disease Prevention

Renata Szymanska,  Pavel Pospisil,  Jerzy Kruk, 
  • First Published: 21 December 2016

Review Article
Open Access

Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins

Jenny Schröter,  Jürgen Schiller, 
  • First Published: 20 December 2016
Review Article
Open Access

Overview of the Role of Vanillin on Redox Status and Cancer Development

Daniel Pereira Bezerra,  Anne Karine Nascimento Soares,  Damião Pergentino de Sousa, 
  • First Published: 19 December 2016
Retraction
Open Access

Retracted: Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties

Oxidative Medicine and Cellular Longevity, 
  • First Published: 19 December 2016

Research Article
Open Access

The Essential Oils of Rhaponticum carthamoides Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities

Ewa Skała,  Patrícia Rijo,  Catarina Garcia,  Przemysław Sitarek,  Danuta Kalemba,  Monika Toma,  Janusz Szemraj,  Dariusz Pytel,  Halina Wysokińska,  Tomasz Śliwiński, 
  • First Published: 18 December 2016
Research Article
Open Access

Low-ω3 Fatty Acid and Soy Protein Attenuate Alcohol-Induced Fatty Liver and Injury by Regulating the Opposing Lipid Oxidation and Lipogenic Signaling Pathways

Karina Reyes-Gordillo,  Ruchi Shah,  Ravi Varatharajalu,  Mamatha Garige,  Leslie C. Leckey,  M. Raj Lakshman, 
  • First Published: 18 December 2016
Research Article
Open Access

Behavior of Oxidative Stress Markers in Alcoholic Liver Cirrhosis Patients

Marina Galicia-Moreno,  Dorothy Rosique-Oramas,  Zaira Medina-Avila,  Tania Álvarez-Torres,  Dalia Falcón,  Fátima Higuera-de la tijera,  Yadira L. Béjar,  Paula Cordero-Pérez,  Linda Muñoz-Espinosa,  José Luis Pérez-Hernández,  David Kershenobich,  Gabriela Gutierrez-Reyes, 
  • First Published: 15 December 2016
Research Article
Open Access

Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondrial Dysfunction in Rat Liver Mitochondria and Hepatocytes

Vojtech Mezera,  Rene Endlicher,  Otto Kucera,  Ondrej Sobotka,  Zdenek Drahota,  Zuzana Cervinkova, 
  • First Published: 15 December 2016
Research Article
Open Access

Gamma-Glutamylcysteine Ethyl Ester Protects against Cyclophosphamide-Induced Liver Injury and Hematologic Alterations via Upregulation of PPARγ and Attenuation of Oxidative Stress, Inflammation, and Apoptosis

Sultan Alqahtani,  Ayman M. Mahmoud, 
  • First Published: 15 December 2016
Review Article
Open Access

Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases

Sha Li,  Ming Hong,  Hor-Yue Tan,  Ning Wang,  Yibin Feng, 
  • First Published: 14 December 2016
Research Article
Open Access

The Early Effect of Carotid Artery Stenting on Antioxidant Capacity and Oxidative Stress in Patients with Carotid Artery Stenosis

Slawomir Michalak,  Wojciech Ambrosius,  Ewa Wysocka,  Mieczyslaw Dziarmaga,  Robert Juszkat,  Andrzej Wykretowicz,  Wojciech Kozubski, 
  • First Published: 13 December 2016
Research Article
Open Access

CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species

Xiao Tang,  Changpo Lin,  Daqiao Guo,  Ruizhe Qian,  Xiaobo Li,  Zhenyu Shi,  Jianjun Liu,  Xu Li,  Longhua Fan, 
  • First Published: 12 December 2016
Research Article
Open Access

Long-Term Alteration of Reactive Oxygen Species Led to Multidrug Resistance in MCF-7 Cells

Juan Cen,  Li Zhang,  Fangfang Liu,  Feng Zhang,  Bian-Sheng Ji, 
  • First Published: 12 December 2016
Research Article
Open Access

Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways

Raffaella Mastrocola,  Claudia Penna,  Francesca Tullio,  Saveria Femminò,  Debora Nigro,  Fausto Chiazza,  Loredana Serpe,  Debora Collotta,  Giuseppe Alloatti,  Mattia Cocco,  Massimo Bertinaria,  Pasquale Pagliaro,  Manuela Aragno,  Massimo Collino, 
  • First Published: 08 December 2016
Research Article
Open Access

Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model

Jazmin M. Pérez-Rojas,  Raquel González-Macías,  Jaime González-Cortes,  Rafael Jurado,  José Pedraza-Chaverri,  Patricia García-López, 
  • First Published: 08 December 2016
Research Article
Open Access

Redox Control of Antioxidant and Antihepatotoxic Activities of Cassia surattensis Seed Extract against Paracetamol Intoxication in Mice: In Vitro and In Vivo Studies of Herbal Green Antioxidant

U. Seeta Uthaya Kumar,  Yeng Chen,  Jagat R. Kanwar,  Sreenivasan Sasidharan, 
  • First Published: 08 December 2016
Research Article
Open Access

Macroautophagy and Selective Mitophagy Ameliorate Chondrogenic Differentiation Potential in Adipose Stem Cells of Equine Metabolic Syndrome: New Findings in the Field of Progenitor Cells Differentiation

Krzysztof Marycz,  Katarzyna Kornicka,  Jakub Grzesiak,  Agnieszka Śmieszek,  Jolanta Szłapka, 
  • First Published: 08 December 2016

Review Article
Open Access

Potential Role of Protein Disulfide Isomerase in Metabolic Syndrome-Derived Platelet Hyperactivity

Renato Simões Gaspar,  Andrés Trostchansky,  Antonio Marcus de Andrade Paes, 
  • First Published: 07 December 2016
Review Article
Open Access

Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases

Yuhei Nishimura,  Hideaki Hara, 
  • First Published: 07 December 2016
Research Article
Open Access

Neurodegeneration and Glial Response after Acute Striatal Stroke: Histological Basis for Neuroprotective Studies

Rafael R. Lima,  Luana N. S. Santana,  Rafael M. Fernandes,  Elder M. Nascimento,  Ana Carolina A. Oliveira,  Luanna M. P. Fernandes,  Enio Mauricio N. dos Santos,  Patrycy Assis N. Tavares,  Ijair Rogério dos Santos,  Adriano Gimarães-Santos,  Walace Gomes-Leal, 
  • First Published: 05 December 2016
Research Article
Open Access

Lycopene Ameliorates Transplant Arteriosclerosis in Vascular Allograft Transplantation by Regulating the NO/cGMP Pathways and Rho-Associated Kinases Expression

Yunqiang He,  Peng Xia,  Hao Jin,  Yan Zhang,  Bicheng Chen,  Ziqiang Xu, 
  • First Published: 05 December 2016
Research Article
Open Access

The Nutraceutical Dehydrozingerone and Its Dimer Counteract Inflammation- and Oxidative Stress-Induced Dysfunction of In Vitro Cultured Human Endothelial Cells: A Novel Perspective for the Prevention and Therapy of Atherosclerosis

Elisabetta Profumo,  Brigitta Buttari,  Daniela D’Arcangelo,  Lavinia Tinaburri,  Maria Antonietta Dettori,  Davide Fabbri,  Giovanna Delogu,  Rachele Riganò, 
  • First Published: 05 December 2016
Research Article
Open Access

Comparing the Behavioural Effects of Exogenous Growth Hormone and Melatonin in Young and Old Wistar Rats

Pere Barceló,  Cristina Nicolau,  Antoni Gamundí,  Maria A. Fiol,  Jesús A. F. Tresguerres,  Mourad Akaârir,  Rubén V. Rial, 
  • First Published: 05 December 2016
Research Article
Open Access

Comparative Analysis of the Interaction between Different Flavonoids and PDIA3

Flavia Giamogante,  Ilaria Marrocco,  Donatella Romaniello,  Margherita Eufemi,  Silvia Chichiarelli,  Fabio Altieri, 
  • First Published: 04 December 2016
Review Article
Open Access

Antioxidant Capacity Determination in Plants and Plant-Derived Products: A Review

Aurelia Magdalena Pisoschi,  Aneta Pop,  Carmen Cimpeanu,  Gabriel Predoi, 
  • First Published: 04 December 2016
Clinical Study
Open Access

Unbalanced Oxidant-Antioxidant Status: A Potential Therapeutic Target for Coronary Chronic Total Occlusion in Very Old Patients

Xia Li,  Youdong Hu,  Fenglin Zhang,  Ying Chen,  Hualan Zhou,  Dianxuan Guo,  Qingna Zhao, 
  • First Published: 01 December 2016
Research Article
Open Access

Monoamine Oxidase Is Overactivated in Left and Right Ventricles from Ischemic Hearts: An Intriguing Therapeutic Target

Maria Elena Manni,  Stefania Rigacci,  Elisabetta Borchi,  Valentina Bargelli,  Caterina Miceli,  Carla Giordano,  Laura Raimondi,  Chiara Nediani, 
  • First Published: 01 December 2016
Research Article
Open Access

PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells

Yanan Niu,  Wen Sun,  Jin-Jian Lu,  Dik-Lung Ma,  Chung-Hang Leung,  Lixia Pei,  Xiuping Chen, 
  • First Published: 30 November 2016
Research Article
Open Access

Adiponectin Protects against Glutamate-Induced Excitotoxicity via Activating SIRT1-Dependent PGC-1α Expression in HT22 Hippocampal Neurons

Liang Yue,  Lei Zhao,  Haixiao Liu,  Xia Li,  Bodong Wang,  Hao Guo,  Li Gao,  Dayun Feng,  Yan Qu, 
  • First Published: 30 November 2016
Review Article
Open Access

Dysfunction of Autophagy: A Possible Mechanism Involved in the Pathogenesis of Vitiligo by Breaking the Redox Balance of Melanocytes

Zhuhui Qiao,  Xiuxiu Wang,  Leihong Xiang,  Chengfeng Zhang, 
  • First Published: 29 November 2016
Research Article
Open Access

The Effects of the Combination of a Refined Carbohydrate Diet and Exposure to Hyperoxia in Mice

Nicia Pedreira Soares,  Keila Karine Duarte Campos,  Karina Braga Pena,  Ana Carla Balthar Bandeira,  André Talvani,  Marcelo Eustáquio Silva,  Frank Silva Bezerra, 
  • First Published: 29 November 2016
Research Article
Open Access

SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model

Siqi Xu,  Youguang Gao,  Qin Zhang,  Siwei Wei,  Zhongqing Chen,  Xingui Dai,  Zhenhua Zeng,  Ke-seng Zhao, 
  • First Published: 28 November 2016
Research Article
Open Access

Dietary Supplementation of Phoenix dactylifera Seeds Enhances Performance, Immune Response, and Antioxidant Status in Broilers

Ali H. El-Far,  Hamada A. Ahmed,  Hazem M. Shaheen, 
  • First Published: 28 November 2016
Research Article
Open Access

Virus Infections on Prion Diseased Mice Exacerbate Inflammatory Microglial Response

Nara Lins,  Luiz Mourão,  Nonata Trévia,  Aline Passos,  José Augusto Farias,  Jarila Assunção,  Amanda Quintairos,  João Bento-Torres,  Marcia Consentino Kronka Sosthenes,  José Antonio Picanço Diniz,  Pedro Fernando da Costa Vasconcelos,  Cristovam Wanderley Picanço-Diniz, 
  • First Published: 27 November 2016
Research Article
Open Access

Skin Aging-Dependent Activation of the PI3K Signaling Pathway via Downregulation of PTEN Increases Intracellular ROS in Human Dermal Fibroblasts

Eun-Mi Noh,  Jinny Park,  Hwa-Ryung Song,  Jeong-Mi Kim,  Minok Lee,  Hyun-Kyung Song,  On-Yu Hong,  Pyoung H. Whang,  Myung-Kwan Han,  Kang-Beom Kwon,  Jong-Suk Kim,  Young-Rae Lee, 
  • First Published: 27 November 2016
Research Article
Open Access

Resolving Contributions of Oxygen-Consuming and ROS-Generating Enzymes at the Synapse

Engy A. Abdel-Rahman,  Ali M. Mahmoud,  Abdullah Aaliya,  Yasmine Radwan,  Basma Yasseen,  Abdelrahman Al-Okda,  Ahmed Atwa,  Eslam Elhanafy,  Moaaz Habashy,  Sameh S. Ali, 
  • First Published: 27 November 2016

Research Article
Open Access

Oxidant Status following Cardiac Surgery with Phosphorylcholine-Coated Extracorporeal Circulation Systems

Ali Can Hatemi,  Kadir Çeviker,  Aybala Tongut,  İlhan Özgöl,  Murat Mert,  Ayşem Kaya, 
  • First Published: 23 November 2016
Research Article
Open Access

Serum from Varicose Patients Induces Senescence-Related Dysfunction of Vascular Endothelium Generating Local and Systemic Proinflammatory Conditions

Justyna Mikuła-Pietrasik,  Paweł Uruski,  Krzysztof Aniukiewicz,  Patrycja Sosińska,  Zbigniew Krasiński,  Andrzej Tykarski,  Krzysztof Książek, 
  • First Published: 23 November 2016
Research Article
Open Access

Effects of Allicin on Hypertension and Cardiac Function in Chronic Kidney Disease

Ehécatl M. A. García-Trejo,  Abraham S. Arellano-Buendía,  Raúl Argüello-García,  María L. Loredo-Mendoza,  Fernando E. García-Arroyo,  Mónica G. Arellano-Mendoza,  María C. Castillo-Hernández,  Gustavo Guevara-Balcázar,  Edilia Tapia,  Laura G. Sánchez-Lozada,  Horacio Osorio-Alonso, 
  • First Published: 21 November 2016
Clinical Study
Open Access

Evidence of a Redox-Dependent Regulation of Immune Responses to Exercise-Induced Inflammation

Alexandra Sakelliou,  Ioannis G. Fatouros,  Ioannis Athanailidis,  Dimitrios Tsoukas,  Athanasios Chatzinikolaou,  Dimitris Draganidis,  Athanasios Z. Jamurtas,  Christina Liacos,  Ioannis Papassotiriou,  Dimitrios Mandalidis,  Kimon Stamatelopoulos,  Meletios A. Dimopoulos,  Asimina Mitrakou, 
  • First Published: 15 November 2016
Research Article
Open Access

Partial Oxygen Pressure Affects the Expression of Prognostic Biomarkers HIF-1 Alpha, Ki67, and CK20 in the Microenvironment of Colorectal Cancer Tissue

Lirong Zhang,  Yu Hu,  Ning Xi,  Jie Song,  Wenjing Huang,  Shanshan Song,  Yiting Liu,  Xianying Liu,  Yingjun Xie, 
  • First Published: 15 November 2016
Research Article
Open Access

Calcium Oxalate Induces Renal Injury through Calcium-Sensing Receptor

Xiaoran Li,  Junhai Ma,  Wei Shi,  Yu Su,  Xu Fu,  Yanlin Yang,  Jianzhong Lu,  Zhongjin Yue, 
  • First Published: 14 November 2016
Research Article
Open Access

Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee (Coffea arabica L.) Bean Residual Press Cake on the Skin Wound Healing

Regina Celis Lopes Affonso,  Ana Paula Lorenzen Voytena,  Simone Fanan,  Heloísa Pitz,  Daniela Sousa Coelho,  Ana Luiza Horstmann,  Aline Pereira,  Virgílio Gavicho Uarrota,  Maria Clara Hillmann,  Lucas Andre Calbusch Varela,  Rosa Maria Ribeiro-do-Valle,  Marcelo Maraschin, 
  • First Published: 14 November 2016
Research Article
Open Access

Colonic and Hepatic Modulation by Lipoic Acid and/or N-Acetylcysteine Supplementation in Mild Ulcerative Colitis Induced by Dextran Sodium Sulfate in Rats

Fabiana Andréa Moura,  Kívia Queiroz de Andrade,  Orlando Roberto Pimentel de Araújo,  Valéria Nunes-Souza,  Juliana Célia de Farias Santos,  Luiza Antas Rabelo,  Marília Oliveira Fonseca Goulart, 
  • First Published: 13 November 2016
Editorial
Open Access

Drug-Metabolizing Enzymes and Metabolic Diseases: Role of Antioxidants

Salah A. Sheweita,  Mahmoud Balbaa,  Samy L. Habib, 
  • First Published: 13 November 2016
Research Article
Open Access

Oral Exposure to Atrazine Induces Oxidative Stress and Calcium Homeostasis Disruption in Spleen of Mice

Shuying Gao,  Zhichun Wang,  Chonghua Zhang,  Liming Jia,  Yang Zhang, 
  • First Published: 10 November 2016
Review Article
Open Access

Oxidative Stress and Liver Cancer: Etiology and Therapeutic Targets

Zhanpeng Wang,  Zhuonan Li,  Yanshuo Ye,  Lijuan Xie,  Wei Li, 
  • First Published: 10 November 2016
Research Article
Open Access

Endogenous n-3 Fatty Acids Alleviate Carbon-Tetrachloride-Induced Acute Liver Injury in Fat-1 Transgenic Mice

Ruibing Feng,  Meng Wang,  Chunyan Yan,  Peng Li,  Meiwan Chen,  Chengwei He,  Jian-Bo Wan, 
  • First Published: 06 November 2016
Research Article
Open Access

The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide

Miao Su,  Tengfei Yu,  Hong Zhang,  Yan Wu,  Xiaoqin Wang,  Gang Li, 
  • First Published: 06 November 2016
Research Article
Open Access

Astragalus Polysaccharide Suppresses 6-Hydroxydopamine-Induced Neurotoxicity in Caenorhabditis elegans

Haifeng Li,  Ruona Shi,  Fei Ding,  Hongyu Wang,  Wenjing Han,  Fangli Ma,  Minghua Hu,  Chung Wah Ma,  Zebo Huang, 
  • First Published: 03 November 2016
Research Article
Open Access

2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside Promotes Expression of the Longevity Gene Klotho

Shuang Ling,  Ju Duan,  Rongzhen Ni,  Jin-Wen Xu, 
  • First Published: 03 November 2016
Research Article
Open Access

(−)-Epicatechin Prevents Blood Pressure Increase and Reduces Locomotor Hyperactivity in Young Spontaneously Hypertensive Rats

M. Kluknavsky,  P. Balis,  A. Puzserova,  J. Radosinska,  A. Berenyiova,  M. Drobna,  S. Lukac,  J. Muchova,  I. Bernatova, 
  • First Published: 03 November 2016

Research Article
Open Access

Protective Effects of Hydrogen Sulfide in the Ageing Kidney

Cui-Lan Hou,  Ming-Jie Wang,  Chen Sun,  Yong Huang,  Sheng Jin,  Xue-Pan Mu,  Ying Chen,  Yi-Chun Zhu, 
  • First Published: 01 November 2016
Research Article
Open Access

Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury

Yue Shang,  Yaw L. Siow,  Cara K. Isaak,  Karmin O, 
  • First Published: 30 October 2016
Research Article
Open Access

The Oxidative and Inflammatory State in Patients with Acute Renal Graft Dysfunction Treated with Tacrolimus

Sandra Carrillo-Ibarra,  José Ignacio Cerrillos-Gutiérrez,  Ariadna Escalante-Núñez,  Enrique Rojas-Campos,  Benjamín Gómez-Navarro,  Sonia Sifuentes-Franco,  Ernesto Germán Cardona-Muñoz,  Alejandra Guillermina Miranda-Díaz, 
  • First Published: 30 October 2016
Research Article
Open Access

Renalase as a Novel Biomarker for Evaluating the Severity of Hepatic Ischemia-Reperfusion Injury

Huili Li,  Jianrong Guo,  Hongli Liu,  Yanfeng Niu,  Lixia Wang,  Kun Huang,  Jiliang Wang, 
  • First Published: 27 October 2016
Research Article
Open Access

Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes

Ye Da Xiao,  Ya Yi Huang,  Hua Xin Wang,  Yang Wu,  Yan Leng,  Min Liu,  Qian Sun,  Zhong-Yuan Xia, 
  • First Published: 27 October 2016
Research Article
Open Access

Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway

Zhaojun Dong,  Haixiao Shang,  Yong Q. Chen,  Li-Long Pan,  Madhav Bhatia,  Jia Sun, 
  • First Published: 26 October 2016
Research Article
Open Access

Differential Expression of NADPH Oxidases Depends on Skeletal Muscle Fiber Type in Rats

Adriano César Carneiro Loureiro,  Igor Coutinho do Rêgo-Monteiro,  Ruy A. Louzada,  Victor Hugo Ortenzi,  Angélica Ponte de Aguiar,  Ewerton Sousa de Abreu,  João Paulo Albuquerque Cavalcanti-de-Albuquerque,  Fabio Hecht,  Ariclécio Cunha de Oliveira,  Vânia Marilande Ceccatto,  Rodrigo S. Fortunato,  Denise P. Carvalho, 
  • First Published: 26 October 2016
Research Article
Open Access

Caspase-3 Deletion Promotes Necrosis in Atherosclerotic Plaques of ApoE Knockout Mice

Mandy O. J. Grootaert,  Dorien M. Schrijvers,  Marthe Hermans,  Viviane O. Van Hoof,  Guido R. Y. De Meyer,  Wim Martinet, 
  • First Published: 26 October 2016
Review Article
Open Access

Schisandrin B: A Double-Edged Sword in Nonalcoholic Fatty Liver Disease

Pou Kuan Leong,  Kam Ming Ko, 
  • First Published: 26 October 2016
Review Article
Open Access

Nrf2 and Notch Signaling in Lung Cancer: Near the Crossroad

Angelo Sparaneo,  Federico Pio Fabrizio,  Lucia Anna Muscarella, 
  • First Published: 25 October 2016
Research Article
Open Access

Phytochemical Content and Pharma-Nutrition Study on Eleutherococcus senticosus Fruits Intractum

Daniel Załuski,  Marta Olech,  Agnieszka Galanty,  Robert Verpoorte,  Rafał Kuźniewski,  Renata Nowak,  Anna Bogucka-Kocka, 
  • First Published: 24 October 2016
Research Article
Open Access

An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation

Han-Lin Chou,  Yao Fong,  Hsin-Hsien Lin,  Eing Mei Tsai,  Jeff Yi-Fu Chen,  Wen-Tsan Chang,  Chang-Yi Wu,  Hui-Min David Wang,  Hurng-Wern Huang,  Chien-Chih Chiu, 
  • First Published: 24 October 2016
Research Article
Open Access

NLRP3 Inflammasome Activation in the Brain after Global Cerebral Ischemia and Regulation by 17β-Estradiol

Roshni Thakkar,  Ruimin Wang,  Gangadhara Sareddy,  Jing Wang,  Dharma Thiruvaiyaru,  Ratna Vadlamudi,  Quanguang Zhang,  Darrell Brann, 
  • First Published: 23 October 2016
Research Article
Open Access

An Explanation of the Underlying Mechanisms for the In Vitro and In Vivo Antiurolithic Activity of Glechoma longituba

Qiang Liang,  Xiaoran Li,  Wangning Zhou,  Yu Su,  Shenbao He,  Shuanglei Cheng,  Jianzhong Lu,  Wenjuan Cao,  Yuke Yan,  Xiaxia Pei,  Jin Qi,  Guangli Xu,  Zhongjin Yue, 
  • First Published: 20 October 2016
Research Article
Open Access

Pomegranate-Derived Polyphenols Reduce Reactive Oxygen Species Production via SIRT3-Mediated SOD2 Activation

Chong Zhao,  Takenori Sakaguchi,  Kosuke Fujita,  Hideyuki Ito,  Norihisa Nishida,  Akifumi Nagatomo,  Yukimasa Tanaka-Azuma,  Yoshinori Katakura, 
  • First Published: 20 October 2016
Research Article
Open Access

Hydrogen Sulfide Regulates the [Ca2+]i Level in the Primary Medullary Neurons

Xiaoni Liu,  Nana Zhang,  Yingjiong Ding,  Dongqing Cao,  Ying Huang,  Xiangjun Chen,  Rui Wang,  Ning Lu, 
  • First Published: 20 October 2016
Research Article
Open Access

Uncoupling of Vascular Nitric Oxide Synthase Caused by Intermittent Hypoxia

Mohammad Badran,  Bisher Abuyassin,  Saeid Golbidi,  Najib Ayas,  Ismail Laher, 
  • First Published: 20 October 2016
Research Article
Open Access

Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus

Han Wu,  Zhen-Qiang Sheng,  Jun Xie,  Ran Li,  Liang Chen,  Guan-Nan Li,  Lian Wang,  Biao Xu, 
  • First Published: 19 October 2016
Editorial
Open Access

Oxidative Stress and Diseases: Clinical Trials and Approaches

Eiichiro Ichiishi,  Xiao-Kang Li,  Eugenio L. Iorio, 
  • First Published: 19 October 2016
Research Article
Open Access

Serum Lipoprotein (a) Levels in Black South African Type 2 Diabetes Mellitus Patients

Jim Joseph,  Farzana Ganjifrockwala,  Grace George, 
  • First Published: 19 October 2016
Review Article
Open Access

Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

Josiel Mileno Mack,  Marissa Giovanna Schamne,  Tuane Bazanella Sampaio,  Renata Aparecida Nedel Pértile,  Pedro Augusto Carlos Magno Fernandes,  Regina P. Markus,  Rui Daniel Prediger, 
  • First Published: 18 October 2016
Research Article
Open Access

Activation of ALDH2 with Low Concentration of Ethanol Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetes Rat Model

Pin-Fang Kang,  Wen-Juan Wu,  Yang Tang,  Ling Xuan,  Su-Dong Guan,  Bi Tang,  Heng Zhang,  Qin Gao,  Hong-Ju Wang, 
  • First Published: 18 October 2016
Review Article
Open Access

New Insights into the Role of Oxidative Stress Mechanisms in the Pathophysiology and Treatment of Multiple Sclerosis

Bożena Adamczyk,  Monika Adamczyk-Sowa, 
  • First Published: 18 October 2016
Review Article
Open Access

Potential Therapeutic Strategies for Hypertension-Exacerbated Cardiotoxicity of Anticancer Drugs

Robin K. Kuriakose,  Rakesh C. Kukreja,  Lei Xi, 
  • First Published: 17 October 2016
Research Article
Open Access

Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis

Cinthia Cristina Sousa de Menezes da Silveira,  Luanna Melo Pereira Fernandes,  Mallone Lopes Silva,  Diandra Araújo Luz,  Antônio Rafael Quadros Gomes,  Marta Chagas Monteiro,  Christiane Schineider Machado,  Yohandra Reyes Torres,  Tatiana Onofre de Lira,  Antonio Gilberto Ferreira,  Enéas Andrade Fontes-Júnior,  Cristiane Socorro Ferraz Maia, 
  • First Published: 16 October 2016
Research Article
Open Access

On the Anticataractogenic Effects of L-Carnosine: Is It Best Described as an Antioxidant, Metal-Chelating Agent or Glycation Inhibitor?

Hamdy Abdelkader,  Michael Longman,  Raid G. Alany,  Barbara Pierscionek, 
  • First Published: 16 October 2016
Review Article
Open Access

Oxidative Stress during HIV Infection: Mechanisms and Consequences

Alexander V. Ivanov,  Vladimir T. Valuev-Elliston,  Olga N. Ivanova,  Sergey N. Kochetkov,  Elizaveta S. Starodubova,  Birke Bartosch,  Maria G. Isaguliants, 
  • First Published: 13 October 2016
Editorial
Open Access

Harmful and Beneficial Role of ROS

Sergio Di Meo,  Tanea T. Reed,  Paola Venditti,  Victor M. Victor, 
  • First Published: 12 October 2016
Review Article
Open Access

Nrf2 Is an Attractive Therapeutic Target for Retinal Diseases

Yasuhiro Nakagami, 
  • First Published: 12 October 2016
Research Article
Open Access

Inhibition of HSP90 Promotes Neural Stem Cell Survival from Oxidative Stress through Attenuating NF-κB/p65 Activation

Qian Liu,  Yun Li,  Wenkai Jiang,  Yunzi Li,  Lin Zhou,  Bing Song,  Xinfeng Liu, 
  • First Published: 12 October 2016
Review Article
Open Access

Oxidative Stress and Salvia miltiorrhiza in Aging-Associated Cardiovascular Diseases

Cheng-Chieh Chang,  Yu-Chun Chang,  Wen-Long Hu,  Yu-Chiang Hung, 
  • First Published: 11 October 2016
Research Article
Open Access

Weaning Induced Hepatic Oxidative Stress, Apoptosis, and Aminotransferases through MAPK Signaling Pathways in Piglets

Zhen Luo,  Wei Zhu,  Qi Guo,  Wenli Luo,  Jing Zhang,  Weina Xu,  Jianxiong Xu, 
  • First Published: 11 October 2016
Review Article
Open Access

Therapeutic Potential of Curcumin for the Treatment of Brain Tumors

Neil V. Klinger,  Sandeep Mittal, 
  • First Published: 11 October 2016
Review Article
Open Access

Role of Antioxidants and Natural Products in Inflammation

Palanisamy Arulselvan,  Masoumeh Tangestani Fard,  Woan Sean Tan,  Sivapragasam Gothai,  Sharida Fakurazi,  Mohd Esa Norhaizan,  S. Suresh Kumar, 
  • First Published: 10 October 2016
Research Article
Open Access

The Chemical Profile of Senna velutina Leaves and Their Antioxidant and Cytotoxic Effects

Jaqueline Ferreira Campos,  David Tsuyoshi Hiramatsu de Castro,  Marcio José Damião,  Heron F. Vieira Torquato,  Edgar J. Paredes-Gamero,  Carlos Alexandre Carollo,  Leticia M. Estevinho,  Kely de Picoli Souza,  Edson Lucas dos Santos, 
  • First Published: 10 October 2016
Research Article
Open Access

In Vitro Anti-AChE, Anti-BuChE, and Antioxidant Activity of 12 Extracts of Eleutherococcus Species

Daniel Załuski,  Rafał Kuźniewski, 
  • First Published: 10 October 2016
Research Article
Open Access

Carvacrol Alleviates Prostate Cancer Cell Proliferation, Migration, and Invasion through Regulation of PI3K/Akt and MAPK Signaling Pathways

Yun Luo,  Jie-Ying Wu,  Min-Hua Lu,  Zhi Shi,  Ning Na,  Jin-Ming Di, 
  • First Published: 10 October 2016
Research Article
Open Access

miR-21 Reduces Hydrogen Peroxide-Induced Apoptosis in c-kit+ Cardiac Stem Cells In Vitro through PTEN/PI3K/Akt Signaling

Wenwen Deng,  Yan Wang,  Xianping Long,  Ranzun Zhao,  Zhenglong Wang,  Zhijiang Liu,  Song Cao,  Bei Shi, 
  • First Published: 10 October 2016
Research Article
Open Access

Erectile Dysfunction Drugs Changed the Protein Expressions and Activities of Drug-Metabolising Enzymes in the Liver of Male Rats

Salah A. Sheweita,  Mona Wally,  Mostafa Hassan, 
  • First Published: 09 October 2016
Research Article
Open Access

Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System

Teresa Carbonell,  Norma Alva,  Sergio Sanchez-Nuño,  Shannamar Dewey,  Aldrin V. Gomes, 
  • First Published: 09 October 2016
Research Article
Open Access

Impact of Oxidative Stress in Premature Aging and Iron Overload in Hemodialysis Patients

Blanca Murillo-Ortiz,  Joel Ramírez Emiliano,  Wendy Ivett Hernández Vázquez,  Sandra Martínez-Garza,  Sergio Solorio-Meza,  Froylán Albarrán-Tamayo,  Edna Ramos-Rodríguez,  Luis Benítez- Bribiesca, 
  • First Published: 05 October 2016
Research Article
Open Access

Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression

Lei Pang,  Yin Cai,  Eva Hoi Ching Tang,  Dan Yan,  Ramoji Kosuru,  Haobo Li,  Michael G. Irwin,  Haichun Ma,  Zhengyuan Xia, 
  • First Published: 04 October 2016
Research Article
Open Access

C1q/TNF-Related Protein 9 Protects Diabetic Rat Heart against Ischemia Reperfusion Injury: Role of Endoplasmic Reticulum Stress

Sanxing Bai,  Liang Cheng,  Yang Yang,  Chongxi Fan,  Dajun Zhao,  Zhigang Qin,  Xiao Feng,  Lin Zhao,  Jipeng Ma,  Xiaowu Wang,  Jian Yang,  Xuezeng Xu,  Dinghua Yi,  Wei Yi, 
  • First Published: 04 October 2016
Editorial
Open Access

Reactive Oxygen Species in Cancer Biology and Anticancer Therapy

Alexandr V. Bazhin,  Pavel P. Philippov,  Svetlana Karakhanova, 
  • First Published: 03 October 2016
Research Article
Open Access

Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo

Xiong Yang,  Hao Ding,  Zhenbang Qin,  Changwen Zhang,  Shiyong Qi,  Hongtuan Zhang,  Tong Yang,  Zhen He,  Kuo Yang,  E Du,  Chunyu Liu,  Yong Xu,  Zhihong Zhang, 
  • First Published: 03 October 2016
Research Article
Open Access

Neuroprotective Effects of Açaí (Euterpe oleracea Mart.) against Rotenone In Vitro Exposure

Alencar Kolinski Machado,  Ana Cristina Andreazza,  Tatiane Morgana da Silva,  Aline Augusti Boligon,  Vanusa do Nascimento,  Gustavo Scola,  Angela Duong,  Francine Carla Cadoná,  Euler Esteves Ribeiro,  Ivana Beatrice Mânica da Cruz, 
  • First Published: 03 October 2016
Editorial
Open Access

Gasotransmitters in Biology and Medicine: Molecular Mechanisms and Drug Targets

Guangdong Yang,  Alp Sener,  Yong Ji,  Yanxi Pei,  Michael D. Pluth, 
  • First Published: 29 September 2016
Research Article
Open Access

The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2

Denise Clavijo-Cornejo,  Karina Martínez-Flores,  Karina Silva-Luna,  Gabriela Angélica Martínez-Nava,  Javier Fernández-Torres,  Yessica Zamudio-Cuevas,  Mónica Guadalupe Santamaría-Olmedo,  Julio Granados-Montiel,  Carlos Pineda,  Alberto López-Reyes, 
  • First Published: 29 September 2016

Review Article
Open Access

Targeting Glial Mitochondrial Function for Protection from Cerebral Ischemia: Relevance, Mechanisms, and the Role of MicroRNAs

Le Li,  Creed M. Stary, 
  • First Published: 29 September 2016
Review Article
Open Access

Role of Oxidative Stress in the Neurocognitive Dysfunction of Obstructive Sleep Apnea Syndrome

Li Zhou,  Ping Chen,  Yating Peng,  Ruoyun Ouyang, 
  • First Published: 28 September 2016
Research Article
Open Access

Oxidative Stress Markers and Their Dynamic Changes in Patients after Acute Ischemic Stroke

Ingrid Žitňanová,  Pavol Šiarnik,  Branislav Kollár,  Mária Chomová,  Petra Pazderová,  Lucia Andrezálová,  Miriam Ježovičová,  Katarína Koňariková,  Lucia Laubertová,  Zuzana Krivošíková,  Laura Slezáková,  Peter Turčáni, 
  • First Published: 28 September 2016
Research Article
Open Access

Upregulation of Heme Oxygenase-1 in Response to Wild Thyme Treatment Protects against Hypertension and Oxidative Stress

Nevena Mihailovic-Stanojevic,  Zoran Miloradović,  Milan Ivanov,  Branko Bugarski,  Đurđica Jovović,  Danijela Karanović,  Una-Jovana Vajić,  Draženka Komes,  Jelica Grujić-Milanović, 
  • First Published: 28 September 2016
Review Article
Open Access

Plant-Derived Agents for Counteracting Cisplatin-Induced Nephrotoxicity

Shreesh Ojha,  Balaji Venkataraman,  Amani Kurdi,  Eglal Mahgoub,  Bassem Sadek,  Mohanraj Rajesh, 
  • First Published: 27 September 2016
Research Article
Open Access

Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice

Jiaming Guo,  Deyun Zhao,  Xiao Lei,  Hainan Zhao,  Yanyong Yang,  Pei Zhang,  Pengfei Liu,  Yang Xu,  Meizhou Zhu,  Hu Liu,  Yuanyuan Chen,  Yunhai Chuai,  Bailong Li,  Fu Gao,  Jianming Cai, 
  • First Published: 27 September 2016
Research Article
Open Access

Nuclear Factor (Erythroid-Derived)-Related Factor 2-Associated Retinal Pigment Epithelial Cell Protection under Blue Light-Induced Oxidative Stress

Kei Takayama,  Hiroki Kaneko,  Keiko Kataoka,  Reona Kimoto,  Shiang-Jyi Hwang,  Fuxiang Ye,  Yosuke Nagasaka,  Taichi Tsunekawa,  Toshiyuki Matsuura,  Norie Nonobe,  Yasuki Ito,  Hiroko Terasaki, 
  • First Published: 27 September 2016
Research Article
Open Access

Blood Levels of Oxidant/Antioxidant Parameters in Rats Infected with Toxoplasma gondii

Somayeh Bahrami,  Ali Shahriari,  Mehdi Tavalla,  Somayeh Azadmanesh,  Hossein Hamidinejat, 
  • First Published: 26 September 2016
Research Article
Open Access

Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment

Peng Zou,  Longhua Liu,  Louise D. Zheng,  Kyle K. Payne,  Masoud H. Manjili,  Michael O. Idowu,  Jinfeng Zhang,  Eva M. Schmelz,  Zhiyong Cheng, 
  • First Published: 26 September 2016
Research Article
Open Access

Bilateral Renal Denervation Ameliorates Isoproterenol-Induced Heart Failure through Downregulation of the Brain Renin-Angiotensin System and Inflammation in Rat

Jian-Dong Li,  Ai-Yuan Cheng,  Yan-Li Huo,  Jie Fan,  Yu-Ping Zhang,  Zhi-Qin Fang,  Hong-Sheng Sun,  Wei Peng,  Jin-Shun Zhang,  Hai-Ping Wang,  Bao-Jian Xue, 
  • First Published: 26 September 2016
Research Article
Open Access

Functional Interactions between BKCaα-Subunit and Annexin A5: Implications in Apoptosis

Stephen P. Brazier,  Vsevolod Telezhkin,  Paul J. Kemp, 
  • First Published: 25 September 2016
Review Article
Open Access

Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?

Tarique Hussain,  Bie Tan,  Yulong Yin,  Francois Blachier,  Myrlene C. B. Tossou,  Najma Rahu, 
  • First Published: 22 September 2016
Research Article
Open Access

Response of Mouse Zygotes Treated with Mild Hydrogen Peroxide as a Model to Reveal Novel Mechanisms of Oxidative Stress-Induced Injury in Early Embryos

Diting Qian,  Zhiling Li,  Yuting Zhang,  Yue Huang,  Que Wu,  Gaizhen Ru,  Man Chen,  Bin Wang, 
  • First Published: 22 September 2016
Review Article
Open Access

Dietary Phytochemicals: Natural Swords Combating Inflammation and Oxidation-Mediated Degenerative Diseases

Md. Asiful Islam,  Fahmida Alam,  Md. Solayman,  Md. Ibrahim Khalil,  Mohammad Amjad Kamal,  Siew Hua Gan, 
  • First Published: 19 September 2016
Research Article
Open Access

Effect of High-Intensity Training in Normobaric Hypoxia on Thoroughbred Skeletal Muscle

Hiroshi Nagahisa,  Kazutaka Mukai,  Hajime Ohmura,  Toshiyuki Takahashi,  Hirofumi Miyata, 
  • First Published: 19 September 2016
Review Article
Open Access

Role of Endogenous Sulfur Dioxide in Regulating Vascular Structural Remodeling in Hypertension

Jia Liu,  Yaqian Huang,  Selena Chen,  Chaoshu Tang,  Hongfang Jin,  Junbao Du, 
  • First Published: 18 September 2016
Research Article
Open Access

Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21Cip1/Waf1 Pathway

Mingyu Zhang,  Yue Du,  Renzhong Lu,  You Shu,  Wei Zhao,  Zhuoyun Li,  Yu Zhang,  Ruixue Liu,  Ti Yang,  Shenjian Luo,  Ming Gao,  Yue Zhang,  Guiye Zhang,  Jiaqi Liu,  Yanjie Lu, 
  • First Published: 15 September 2016
Research Article
Open Access

Antioxidant-Enhancing Property of the Polar Fraction of Mangosteen Pericarp Extract and Evaluation of Its Safety in Humans

Wichit Suthammarak,  Pornpayom Numpraphrut,  Ratiya Charoensakdi,  Neelobol Neungton,  Vachara Tunrungruangtavee,  Nattapon Jaisupa,  Suwit Charoensak,  Primchanien Moongkarndi,  Weerasak Muangpaisan, 
  • First Published: 15 September 2016
Review Article
Open Access

Targeting Antitumor Immune Response for Enhancing the Efficacy of Photodynamic Therapy of Cancer: Recent Advances and Future Perspectives

Yamin Yang,  Yue Hu,  Hongjun Wang, 
  • First Published: 08 September 2016
Research Article
Open Access

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta

Javier Palacios,  Fredi Cifuentes,  Jaime A. Valderrama,  Julio Benites,  David Ríos,  Constanza González,  Mario Chiong,  Benjamín Cartes-Saavedra,  Carlos Lafourcade,  Ursula Wyneken,  Pamela González,  Gareth I. Owen,  Fabián Pardo,  Luis Sobrevia,  Pedro Buc Calderon, 
  • First Published: 08 September 2016
Research Article
Open Access

Properties of Flavonoids Isolated from the Bark of Eysenhardtia polystachya and Their Effect on Oxidative Stress in Streptozotocin-Induced Diabetes Mellitus in Mice

Rosa Martha Perez-Gutierrez,  Abraham Heriberto Garcia-Campoy,  Alethia Muñiz-Ramirez, 
  • First Published: 07 September 2016
Review Article
Open Access

The Multiple Facets of Lutein: A Call for Further Investigation in the Perinatal Period

Serafina Perrone,  Monica Tei,  Mariangela Longini,  Giuseppe Buonocore, 
  • First Published: 07 September 2016
Review Article
Open Access

Therapeutic Strategies for Oxidative Stress-Related Cardiovascular Diseases: Removal of Excess Reactive Oxygen Species in Adult Stem Cells

Hyunyun Kim,  Jisoo Yun,  Sang-Mo Kwon, 
  • First Published: 07 September 2016
Research Article
Open Access

Allium cepa Extract and Quercetin Protect Neuronal Cells from Oxidative Stress via PKC-ε Inactivation/ERK1/2 Activation

Bo Kyung Lee,  Yi-Sook Jung, 
  • First Published: 07 September 2016
Review Article
Open Access

Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective

Yingke Zhao,  Yue Liu,  Keji Chen, 
  • First Published: 07 September 2016
Research Article
Open Access

Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice

Xiu Hong Yang,  Yu Pan,  Xiao Li Zhan,  Bao Long Zhang,  Li Li Guo,  Hui Min Jin, 
  • First Published: 06 September 2016
Clinical Study
Open Access

Training Enhances Immune Cells Mitochondrial Biosynthesis, Fission, Fusion, and Their Antioxidant Capabilities Synergistically with Dietary Docosahexaenoic Supplementation

Carla Busquets-Cortés,  Xavier Capó,  Miquel Martorell,  Josep A. Tur,  Antoni Sureda,  Antoni Pons, 
  • First Published: 06 September 2016
Review Article
Open Access

Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration

Janusz Blasiak,  Russel J. Reiter,  Kai Kaarniranta, 
  • First Published: 05 September 2016
Research Article
Open Access

Rosmarinic Acid and Melissa officinalis Extracts Differently Affect Glioblastoma Cells

Kristina Ramanauskiene,  Raimondas Raudonis,  Daiva Majiene, 
  • First Published: 05 September 2016
Research Article
Open Access

Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways

Xu Wu,  Wenyu Gu,  Huan Lu,  Chengying Liu,  Biyun Yu,  Hui Xu,  Yaodong Tang,  Shanqun Li,  Jian Zhou,  Chuan Shao, 
  • First Published: 05 September 2016
Research Article
Open Access

Antioxidant and Vasodilator Activity of Ugni molinae Turcz. (Murtilla) and Its Modulatory Mechanism in Hypotensive Response

Ignacio Jofré,  Cesar Pezoa,  Magdalena Cuevas,  Erick Scheuermann,  Irlan Almeida Freires,  Pedro Luiz Rosalen,  Severino Matias de Alencar,  Fernando Romero, 
  • First Published: 04 September 2016
Letter to the Editor
Open Access

Response to: Comment on “The Impact of Chronic Tobacco Smoking on Retinal and Choroidal Thickness in Greek Population”

Marilita M. Moschos,  Eirini Nitoda,  Konstantinos Laios,  Dimitrios S. Ladas,  Irini P. Chatziralli, 
  • First Published: 01 September 2016

Research Article
Open Access

Altered Striatocerebellar Metabolism and Systemic Inflammation in Parkinson’s Disease

Chiun-Chieh Yu,  Meng-Hsiang Chen,  Cheng-Hsien Lu,  Yung-Cheng Huang,  Hsiu-Ling Chen,  Nai-Wen Tsai,  Hung-Chen Wang,  I-Hsiao Yang,  Shau-Hsuan Li,  Wei-Che Lin, 
  • First Published: 01 September 2016
Research Article
Open Access

Thioredoxin Binding Protein-2 Regulates Autophagy of Human Lens Epithelial Cells under Oxidative Stress via Inhibition of Akt Phosphorylation

Jiaojie Zhou,  Ke Yao,  Yidong Zhang,  Guangdi Chen,  Kairan Lai,  Houfa Yin,  Yibo Yu, 
  • First Published: 31 August 2016
Research Article
Open Access

Apigenin Attenuates Oxidative Injury in ARPE-19 Cells thorough Activation of Nrf2 Pathway

Xinrong Xu,  Min Li,  Weiwei Chen,  Haitao Yu,  Yan Yang,  Li Hang, 
  • First Published: 31 August 2016
Research Article
Open Access

Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation

Yihan Zhang,  Dongdong Yuan,  Weifeng Yao,  Qianqian Zhu,  Yue Liu,  Fei Huang,  Jiayu Feng,  Xi Chen,  Yong Huang,  Xinjin Chi,  Ziqing Hei, 
  • First Published: 31 August 2016
Research Article
Open Access

Inhibition of Glucose-6-Phosphate Dehydrogenase Could Enhance 1,4-Benzoquinone-Induced Oxidative Damage in K562 Cells

Juan Zhang,  Meng Cao,  Wenwen Yang,  Fengmei Sun,  Cheng Xu,  Lihong Yin,  Yuepu Pu, 
  • First Published: 31 August 2016
Editorial
Open Access

Vanadium Toxicological Potential versus Its Pharmacological Activity: New Developments and Research

Agnieszka Ścibior,  Juan Llopis,  Alvin A. Holder,  Mario Altamirano-Lozano, 
  • First Published: 29 August 2016
Review Article
Open Access

Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases

Maurizio Forte,  Valeria Conti,  Antonio Damato,  Mariateresa Ambrosio,  Annibale A. Puca,  Sebastiano Sciarretta,  Giacomo Frati,  Carmine Vecchione,  Albino Carrizzo, 
  • First Published: 29 August 2016
Research Article
Open Access

Alterations in Red Blood Cell Functionality Induced by an Indole Scaffold Containing a Y-Iminodiketo Moiety: Potential Antiproliferative Conditions

Angela Scala,  Silvana Ficarra,  Annamaria Russo,  Davide Barreca,  Elena Giunta,  Antonio Galtieri,  Giovanni Grassi,  Ester Tellone, 
  • First Published: 29 August 2016
Research Article
Open Access

Cathepsin B Regulates Collagen Expression by Fibroblasts via Prolonging TLR2/NF-κB Activation

Xue Li,  Zhou Wu,  Junjun Ni,  Yicong Liu,  Jie Meng,  Weixian Yu,  Hiroshi Nakanishi,  Yanmin Zhou, 
  • First Published: 28 August 2016
Research Article
Open Access

Açai (Euterpe oleracea Mart.) Upregulates Paraoxonase 1 Gene Expression and Activity with Concomitant Reduction of Hepatic Steatosis in High-Fat Diet-Fed Rats

Renata Rebeca Pereira,  Isabel Cristina Mallosto Emerich de Abreu,  Joyce Ferreira da Costa Guerra,  Nara Nunes Lage,  Juliana Márcia Macedo Lopes,  Maísa Silva,  Wanderson Geraldo de Lima,  Marcelo Eustáquio Silva,  Maria Lucia Pedrosa, 
  • First Published: 25 August 2016
Research Article
Open Access

Oxidation-Reduction Potential as a Biomarker for Severity and Acute Outcome in Traumatic Brain Injury

Kimberly B. Bjugstad,  Leonard T. Rael,  Stewart Levy,  Matthew Carrick,  Charles W. Mains,  Denetta S. Slone,  David Bar-Or, 
  • First Published: 25 August 2016
Research Article
Open Access

Protection of Pentoxifylline against Testis Injury Induced by Intermittent Hypobaric Hypoxia

Chen Yao,  Gang Li,  Yeyong Qian,  Ming Cai,  Hong Yin,  Li Xiao,  Wei Tang,  Fengjie Guo,  Bingyi Shi, 
  • First Published: 25 August 2016
Research Article
Open Access

Differential Regulation of the Extracellular Cysteine/Cystine Redox State (EhCySS) by Lung Fibroblasts from Young and Old Mice

Walter H. Watson,  Tom J. Burke,  Igor N. Zelko,  Edilson Torres-González,  Jeffrey D. Ritzenthaler,  Jesse Roman, 
  • First Published: 25 August 2016
Review Article
Open Access

The Janus-Faced Role of Antioxidants in Cancer Cachexia: New Insights on the Established Concepts

Mohamad Assi,  Amélie Rébillard, 
  • First Published: 24 August 2016
Research Article
Open Access

Hydrogen Sulfide Improves Endothelial Dysfunction via Downregulating BMP4/COX-2 Pathway in Rats with Hypertension

Lin Xiao,  Jing-Hui Dong,  Sheng Jin,  Hong-Mei Xue,  Qi Guo,  Xu Teng,  Yu-Ming Wu, 
  • First Published: 23 August 2016
Review Article
Open Access

Cell Death and Heart Failure in Obesity: Role of Uncoupling Proteins

Angélica Ruiz-Ramírez,  Ocarol López-Acosta,  Miguel Angel Barrios-Maya,  Mohammed El-Hafidi, 
  • First Published: 23 August 2016
Research Article
Open Access

AMP-Activated Protein Kinase Attenuates High Salt-Induced Activation of Epithelial Sodium Channels (ENaC) in Human Umbilical Vein Endothelial Cells

Wei-Wan Zheng,  Xin-Yuan Li,  Hui-Bin Liu,  Zi-Rui Wang,  Qing-Qing Hu,  Yu-Xia Li,  Bin-Lin Song,  Jie Lou,  Qiu-Shi Wang,  He-Ping Ma,  Zhi-Ren Zhang, 
  • First Published: 22 August 2016
Research Article
Open Access

Functionalized Fullerene Increases NF-κB Activity and Blocks Genotoxic Effect of Oxidative Stress in Serum-Starving Human Embryo Lung Diploid Fibroblasts

E. S. Ershova,  V. A. Sergeeva,  V. J. Tabakov,  L. A. Kameneva,  L. N. Porokhovnik,  I. I. Voronov,  E. A. Khakina,  P. A. Troshin,  S. I. Kutsev,  N. N. Veiko,  S. V. Kostyuk, 
  • First Published: 21 August 2016
Research Article
Open Access

Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice

Natalia Nuño-Lámbarri,  Mayra Domínguez-Pérez,  Anna Baulies-Domenech,  Maria J. Monte,  Jose J. G. Marin,  Patricia Rosales-Cruz,  Verónica Souza,  Roxana U. Miranda,  Leticia Bucio,  Eduardo E. Montalvo-Jave,  María Concepción Gutiérrez-Ruiz,  Carmen García-Ruiz,  José C. Fernández-Checa,  Luis Enrique Gomez-Quiroz, 
  • First Published: 21 August 2016
Research Article
Open Access

A Case-Control Study on the Oxidative Balance of 50% Autologous Serum Eye Drops

Patrícia Ioschpe Gus,  Diane Marinho,  Samira Zelanis,  Adriane Belló-Klein,  Claudete Locatelli,  Felipe Nicola,  Ana Laura Kunzler,  Tania Regina Gatelli Fernandes,  Cristina Campos Carraro,  Luciene Barbosa, 
  • First Published: 21 August 2016
Review Article
Open Access

Gsk3 Signalling and Redox Status in Bipolar Disorder: Evidence from Lithium Efficacy

Antonina Luca,  Carmela Calandra,  Maria Luca, 
  • First Published: 18 August 2016
Research Article
Open Access

Lower Superoxide Dismutase 2 (SOD2) Protein Content in Mononuclear Cells Is Associated with Better Survival in Patients with Hemodialysis Therapy

Katharina Krueger,  Jianlin Shen,  Alexandra Maier,  Martin Tepel,  Alexandra Scholze, 
  • First Published: 18 August 2016
Research Article
Open Access

In Vitro Evaluation of the Antioxidant Activity and Wound Healing Properties of Jaboticaba (Plinia peruviana) Fruit Peel Hydroalcoholic Extract

Heloisa da S. Pitz,  Aline Pereira,  Mayara B. Blasius,  Ana Paula L. Voytena,  Regina C. L. Affonso,  Simone Fanan,  Adriana C. D. Trevisan,  Rosa M. Ribeiro-do-Valle,  Marcelo Maraschin, 
  • First Published: 18 August 2016
Research Article
Open Access

Effect of Cross-Sex Hormonal Replacement on Antioxidant Enzymes in Rat Retroperitoneal Fat Adipocytes

Israel Pérez-Torres,  Verónica Guarner-Lans,  Alejandra Zúñiga-Muñoz,  Rodrigo Velázquez Espejel,  Alfredo Cabrera-Orefice,  Salvador Uribe-Carvajal,  Natalia Pavón, 
  • First Published: 18 August 2016
Review Article
Open Access

Mitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old Characters

Andrea del Campo,  Enrique Jaimovich,  Maria Florencia Tevy, 
  • First Published: 18 August 2016
Research Article
Open Access

Creatine Prevents the Structural and Functional Damage to Mitochondria in Myogenic, Oxidatively Stressed C2C12 Cells and Restores Their Differentiation Capacity

Elena Barbieri,  Michele Guescini,  Cinzia Calcabrini,  Luciana Vallorani,  Anna Rita Diaz,  Carmela Fimognari,  Barbara Canonico,  Francesca Luchetti,  Stefano Papa,  Michela Battistelli,  Elisabetta Falcieri,  Vanina Romanello,  Marco Sandri,  Vilberto Stocchi,  Caterina Ciacci,  Piero Sestili, 
  • First Published: 17 August 2016
Review Article
Open Access

Role of NADPH Oxidase in Metabolic Disease-Related Renal Injury: An Update

Cheng Wan,  Hua Su,  Chun Zhang, 
  • First Published: 15 August 2016
Research Article
Open Access

Identification of MicroRNAs Involved in Growth Arrest and Apoptosis in Hydrogen Peroxide-Treated Human Hepatocellular Carcinoma Cell Line HepG2

Yuan Luo,  Xinyu Wen,  Ling Wang,  Jing Gao,  Zi Wang,  Chunyan Zhang,  Pengjun Zhang,  Chengrong Lu,  Lianning Duan,  Yaping Tian, 
  • First Published: 15 August 2016
Research Article
Open Access

Parkin Protects against Oxygen-Glucose Deprivation/Reperfusion Insult by Promoting Drp1 Degradation

Jiayu Tang,  Zhiping Hu,  Jieqiong Tan,  Sonlin Yang,  Liuwang Zeng, 
  • First Published: 14 August 2016
Review Article
Open Access

Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus

Ji Yang,  Xue Yang,  Hejian Zou,  Ming Li, 
  • First Published: 11 August 2016
Research Article
Open Access

Hydrogen Sulfide Alleviates Postharvest Senescence of Grape by Modulating the Antioxidant Defenses

Zhi-Jing Ni,  Kang-Di Hu,  Chang-Bing Song,  Run-Hui Ma,  Zhi-Rong Li,  Ji-Lian Zheng,  Liu-Hui Fu,  Zhao-Jun Wei,  Hua Zhang, 
  • First Published: 10 August 2016
Review Article
Open Access

An Update of Microsomal Prostaglandin E Synthase-1 and PGE2 Receptors in Cardiovascular Health and Diseases

Guangrui Yang,  Lihong Chen, 
  • First Published: 09 August 2016
Research Article
Open Access

Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways

Kang Li,  Luobu Gesang,  Zeng Dan,  Lamu Gusang, 
  • First Published: 09 August 2016
Review Article
Open Access

Mitochondrial Dysfunction Contributes to Hypertensive Target Organ Damage: Lessons from an Animal Model of Human Disease

Speranza Rubattu,  Rosita Stanzione,  Massimo Volpe, 
  • First Published: 09 August 2016
Editorial
Open Access

Oxidative Stress in Chronic Kidney Disease

Alexandra Scholze,  Joachim Jankowski,  José Pedraza-Chaverri,  Pieter Evenepoel, 
  • First Published: 08 August 2016
Research Article
Open Access

Short-Term Effects of Chlorpromazine on Oxidative Stress in Erythrocyte Functionality: Activation of Metabolism and Membrane Perturbation

Silvana Ficarra,  Annamaria Russo,  Davide Barreca,  Elena Giunta,  Antonio Galtieri,  Ester Tellone, 
  • First Published: 08 August 2016
Research Article
Open Access

High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis

Johanna Abrigo,  Juan Carlos Rivera,  Javier Aravena,  Daniel Cabrera,  Felipe Simon,  Fernando Ezquer,  Marcelo Ezquer,  Claudio Cabello-Verrugio, 
  • First Published: 08 August 2016
Review Article
Open Access

Gasotransmitters in Gametogenesis and Early Development: Holy Trinity for Assisted Reproductive Technology—A Review

Jan Nevoral,  Jean-Francois Bodart,  Jaroslav Petr, 
  • First Published: 08 August 2016
Research Article
Open Access

High-Fat Diet Induces Oxidative Stress and MPK2 and HSP83 Gene Expression in Drosophila melanogaster

Mariane Trindade de Paula,  Márcia Rósula Poetini Silva,  Stífani Machado Araujo,  Vandreza Cardoso Bortolotto,  Luana Barreto Meichtry,  Ana Paula Pegoraro Zemolin,  Gabriel L. Wallau,  Cristiano Ricardo Jesse,  Jeferson Luís Franco,  Thaís Posser,  Marina Prigol, 
  • First Published: 07 August 2016
Research Article
Open Access

Binge Drinking of Ethanol during Adolescence Induces Oxidative Damage and Morphological Changes in Salivary Glands of Female Rats

Nathalia Carolina Fernandes Fagundes,  Luanna Melo Pereira Fernandes,  Ricardo Sousa de Oliveira Paraense,  Paulo Mecenas Alves de Farias-Junior,  Francisco Bruno Teixeira,  Sergio Melo Alves-Junior,  João de Jesus Viana Pinheiro,  Maria Elena Crespo-López,  Cristiane Socorro Ferraz Maia,  Rafael Rodrigues Lima, 
  • First Published: 07 August 2016
Research Article
Open Access

Prophylactic Role of Oral Melatonin Administration on Neurogenesis in Adult Balb/C Mice during REM Sleep Deprivation

Gabriela López-Armas,  Mario Eduardo Flores-Soto,  Verónica Chaparro-Huerta,  Luis Felipe Jave-Suarez,  Sofía Soto-Rodríguez,  Iryna Rusanova,  Dario Acuña-Castroviejo,  Oscar González-Perez,  Rocío Elizabeth González-Castañeda, 
  • First Published: 07 August 2016
Research Article
Open Access

The Role of Metformin in Controlling Oxidative Stress in Muscle of Diabetic Rats

Danielle Diniz Vilela,  Leonardo Gomes Peixoto,  Renata Roland Teixeira,  Nathalia Belele Baptista,  Douglas Carvalho Caixeta,  Adriele Vieira de Souza,  Hélen Lara Machado,  Mariana Nunes Pereira,  Robinson Sabino-Silva,  Foued Salmen Espindola, 
  • First Published: 04 August 2016
Review Article
Open Access

Roles of Reactive Oxygen Species in Anticancer Therapy with Salvia miltiorrhiza Bunge

Yu-Chiang Hung,  Tai-Long Pan,  Wen-Long Hu, 
  • First Published: 04 August 2016
Research Article
Open Access

Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet

Mahmoud Balbaa,  Marwa El-Zeftawy,  Doaa Ghareeb,  Nabil Taha,  Abdel Wahab Mandour, 
  • First Published: 04 August 2016
Review Article
Open Access

Systemic Redox Imbalance in Chronic Kidney Disease: A Systematic Review

Konstantina P. Poulianiti,  Antonia Kaltsatou,  Georgia I. Mitrou,  Athanasios Z. Jamurtas,  Yiannis Koutedakis,  Maria Maridaki,  Ioannis Stefanidis,  Giorgos K. Sakkas,  Christina Karatzaferi, 
  • First Published: 03 August 2016
Research Article
Open Access

HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway

Yanlan Chen,  Wen Huang,  Wenlin Jiang,  Xianghong Wu,  Biao Ye,  Xiaoting Zhou, 
  • First Published: 02 August 2016
Review Article
Open Access

Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches

Ioana Miruna Balmus,  Alin Ciobica,  Iulia Antioch,  Romeo Dobrin,  Daniel Timofte, 
  • First Published: 01 August 2016
Research Article
Open Access

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

Xiao-Hui Guan,  Xiao-Hong Liu,  Xuan Hong,  Ning Zhao,  Yun-Fei Xiao,  Ling-Fang Wang,  Ling Tang,  Kai Jiang,  Yi-Song Qian,  Ke-Yu Deng,  Guangju Ji,  Mingui Fu,  Hong-Bo Xin, 
  • First Published: 31 July 2016
Research Article
Open Access

Hyperbilirubinemia Protects against Aging-Associated Inflammation and Metabolic Deterioration

Jaroslav Zelenka,  Aleš Dvořák,  Lukáš Alán,  Marie Zadinová,  Martin Haluzík,  Libor Vítek, 
  • First Published: 31 July 2016
Review Article
Open Access

Reactive Oxygen Species Regulate T Cell Immune Response in the Tumor Microenvironment

Xinfeng Chen,  Mengjia Song,  Bin Zhang,  Yi Zhang, 
  • First Published: 28 July 2016
Research Article
Open Access

The Beneficial Effects of Renal Transplantation on Altered Oxidative Status of ESRD Patients

José Ignacio Cerrillos-Gutiérrez,  Alejandra Guillermina Miranda-Díaz,  Priscila Preciado-Rojas,  Benjamín Gómez-Navarro,  Sonia Sifuentes-Franco,  Sandra Carrillo-Ibarra,  Jorge Andrade-Sierra,  Enrique Rojas-Campos,  Alfonso Martín Cueto-Manzano, 
  • First Published: 28 July 2016
Research Article
Open Access

Antipsychotic Treatment Reduces Indices of Oxidative Stress in First-Episode Psychosis Patients

Kärt Kriisa,  Liina Haring,  Eero Vasar,  Kati Koido,  Sven Janno,  Veiko Vasar,  Kersti Zilmer,  Mihkel Zilmer, 
  • First Published: 27 July 2016
Research Article
Open Access

Xanthine Oxidase-Derived ROS Display a Biphasic Effect on Endothelial Cells Adhesion and FAK Phosphorylation

Meriem H. Ben-Mahdi,  Pham My-Chan Dang,  Marie-Anne Gougerot-Pocidalo,  Yvonne O’Dowd,  Jamel El-Benna,  Catherine Pasquier, 
  • First Published: 27 July 2016
Research Article
Open Access

Grape Powder Improves Age-Related Decline in Mitochondrial and Kidney Functions in Fischer 344 Rats

Indira Pokkunuri,  Quaisar Ali,  Mohammad Asghar, 
  • First Published: 27 July 2016
Research Article
Open Access

Oxidative Stress as Estimated by Gamma-Glutamyl Transferase Levels Amplifies the Alkaline Phosphatase-Dependent Risk for Mortality in ESKD Patients on Dialysis

Claudia Torino,  Francesco Mattace-Raso,  Jan L. C. M. van Saase,  Maurizio Postorino,  Giovanni Luigi Tripepi,  Francesca Mallamaci,  Carmine Zoccali,  PROGREDIRE Study Group, 
  • First Published: 25 July 2016
Research Article
Open Access

Hydrogen Sulfide Protects against Chronic Unpredictable Mild Stress-Induced Oxidative Stress in Hippocampus by Upregulation of BDNF-TrkB Pathway

Min Hu,  Wei Zou,  Chun-Yan Wang,  Xi Chen,  Hui-Ying Tan,  Hai-Ying Zeng,  Ping Zhang,  Hong-Feng Gu,  Xiao-Qing Tang, 
  • First Published: 25 July 2016
Research Article
Open Access

Low-Dose Methylmercury-Induced Apoptosis and Mitochondrial DNA Mutation in Human Embryonic Neural Progenitor Cells

Xinjin Wang,  Mengling Yan,  Lina Zhao,  Qing Wu,  Chunhua Wu,  Xiuli Chang,  Zhijun Zhou, 
  • First Published: 21 July 2016
Research Article
Open Access

Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and Nonexposed In Utero to Tobacco Smoke

Magdalena Chełchowska,  Jadwiga Ambroszkiewicz,  Joanna Gajewska,  Grażyna Rowicka,  Tomasz M. Maciejewski,  Joanna Mazur, 
  • First Published: 20 July 2016
Editorial
Open Access

Redox Imbalance and Stroke

Ruidong Ye,  Ming Shi,  Qian Liu,  Jieli Chen, 
  • First Published: 19 July 2016
Research Article
Open Access

Punicalagin Induces Serum Low-Density Lipoprotein Influx to Macrophages

Dana Atrahimovich,  Soliman Khatib,  Shifra Sela,  Jacob Vaya,  Abraham O. Samson, 
  • First Published: 19 July 2016
Research Article
Open Access

Oxidative Stress Assessment in Response to Ultraendurance Exercise: Thiols Redox Status and ROS Production according to Duration of a Competitive Race

Alessandra Vezzoli,  Cinzia Dellanoce,  Simona Mrakic-Sposta,  Michela Montorsi,  Sarah Moretti,  Annamaria Tonini,  Lorenza Pratali,  Roberto Accinni, 
  • First Published: 18 July 2016
Review Article
Open Access

“Cumulative Stress”: The Effects of Maternal and Neonatal Oxidative Stress and Oxidative Stress-Inducible Genes on Programming of Atopy

Sara Manti,  Lucia Marseglia,  Gabriella D’Angelo,  Caterina Cuppari,  Erika Cusumano,  Teresa Arrigo,  Eloisa Gitto,  Carmelo Salpietro, 
  • First Published: 18 July 2016
Research Article
Open Access

Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress and Inflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinase and Nuclear Factor-Kappa B

Yuhan Tang,  Juan Li,  Chao Gao,  Yanyan Xu,  Yanyan Li,  Xiao Yu,  Jing Wang,  Liegang Liu,  Ping Yao, 
  • First Published: 18 July 2016
Letter to the Editor
Open Access

Comment on “Use of Carnosine for Oxidative Stress Reduction in Different Pathologies”

S. V. Jargin, 
  • First Published: 17 July 2016

Research Article
Open Access

Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells

Han Sung Kim,  Tae-Young Han,  Yeong-Min Yoo, 
  • First Published: 17 July 2016
Research Article
Open Access

Antioxidant and Antihyperlipidemic Effects of Campomanesia adamantium O. Berg Root

Priscilla Pereira de Toledo Espindola,  Paola dos Santos da Rocha,  Carlos Alexandre Carollo,  Wanderlei Onofre Schmitz,  Zefa Valdivina Pereira,  Maria do Carmo Vieira,  Edson Lucas dos Santos,  Kely de Picoli Souza, 
  • First Published: 14 July 2016
Research Article
Open Access

Erythropoietin Restores Long-Term Neurocognitive Function Involving Mechanisms of Neuronal Plasticity in a Model of Hyperoxia-Induced Preterm Brain Injury

Daniela Hoeber,  Marco Sifringer,  Yohan van de Looij,  Josephine Herz,  Stéphane V. Sizonenko,  Karina Kempe,  Meray Serdar,  Joanna Palasz,  Martin Hadamitzky,  Stefanie Endesfelder,  Joachim Fandrey,  Ursula Felderhoff-Müser,  Ivo Bendix, 
  • First Published: 14 July 2016
Editorial
Open Access

Mitochondrial Health in Aging and Age-Related Metabolic Disease

David Sebastián,  Rebeca Acín-Pérez,  Katsutaro Morino, 
  • First Published: 13 July 2016
Review Article
Open Access

Role of ROS and RNS Sources in Physiological and Pathological Conditions

Sergio Di Meo,  Tanea T. Reed,  Paola Venditti,  Victor Manuel Victor, 
  • First Published: 12 July 2016
Research Article
Open Access

[Retracted] Protective Effects of Soy Oligopeptides in Ultraviolet B-Induced Acute Photodamage of Human Skin

Bing-rong Zhou,  Li-wen Ma,  Juan Liu,  Jia-an Zhang,  Yang Xu,  Di Wu,  Felicia Permatasari,  Dan Luo, 
  • First Published: 12 July 2016

Review Article
Open Access

Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones

Jennifer Pichette,  Jeffrey Gagnon, 
  • First Published: 11 July 2016
Review Article
Open Access

Bioactivity of Polyphenols: Preventive and Adjuvant Strategies toward Reducing Inflammatory Bowel Diseases—Promises, Perspectives, and Pitfalls

Anouk Kaulmann,  Torsten Bohn, 
  • First Published: 10 July 2016
Editorial
Open Access

Redox Signaling and Myocardial Cell Death: Molecular Mechanisms and Drug Targets

Mohanraj Rajesh,  Lu Cai,  Partha Mukhopadhyay,  Srinivasan Vedantham, 
  • First Published: 03 July 2016
Research Article
Open Access

Glutathione as a Biomarker in Parkinson’s Disease: Associations with Aging and Disease Severity

Laurie K. Mischley,  Leanna J. Standish,  Noel S. Weiss,  Jeannie M. Padowski,  Terrance J. Kavanagh,  Collin C. White,  Michael E. Rosenfeld, 
  • First Published: 30 June 2016
Review Article
Open Access

Neoatherosclerosis after Drug-Eluting Stent Implantation: Roles and Mechanisms

Yuanyuan Cui,  Yue Liu,  Fuhai Zhao,  Dazhuo Shi,  Keji Chen, 
  • First Published: 30 June 2016
Research Article
Open Access

Tissue Kallikrein Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the B2R-ERK1/2-CREB-Bcl-2 Signaling Pathway in Diabetic Rats

Ruifeng Shi,  Kunxiong Yuan,  Bin Hu,  Hongfei Sang,  Lizhi Zhou,  Yi Xie,  Lili Xu,  Qinqin Cao,  Xin Chen,  Lingling Zhao,  Yunyun Xiong,  Gelin Xu,  Xinfeng Liu,  Ling Liu,  Renliang Zhang, 
  • First Published: 30 June 2016
Research Article
Open Access

Antioxidant, Cytotoxic, and Antiproliferative Activities and Total Polyphenol Contents of the Extracts of Geissospermum reticulatum Bark

Joanna J. Sajkowska-Kozielewicz,  Paweł Kozielewicz,  Nicholas M. Barnes,  Iwona Wawer,  Katarzyna Paradowska, 
  • First Published: 29 June 2016
Research Article
Open Access

Identification of Redox and Glucose-Dependent Txnip Protein Interactions

Benjamin J. Forred,  Skyla Neuharth,  Dae In Kim,  Michael W. Amolins,  Khatereh Motamedchaboki,  Kyle J. Roux,  Peter F. Vitiello, 
  • First Published: 29 June 2016
Research Article
Open Access

Hyperglycemia Promotes the Epithelial-Mesenchymal Transition of Pancreatic Cancer via Hydrogen Peroxide

Wei Li,  Lun Zhang,  Xin Chen,  Zhengdong Jiang,  Liang Zong,  Qingyong Ma, 
  • First Published: 28 June 2016
Research Article
Open Access

Sulforaphane Ameliorates Bladder Dysfunction through Activation of the Nrf2-ARE Pathway in a Rat Model of Partial Bladder Outlet Obstruction

Chong Liu,  Huan Xu,  Shi Fu,  Yanbo Chen,  Qi Chen,  Zhikang Cai,  Juan Zhou,  Zhong Wang, 
  • First Published: 28 June 2016
Research Article
Open Access

Constituents of French Marigold (Tagetes patula L.) Flowers Protect Jurkat T-Cells against Oxidative Stress

Irakli Chkhikvishvili,  Tamar Sanikidze,  Nunu Gogia,  Maia Enukidze,  Marine Machavariani,  Nana Kipiani,  Yakov Vinokur,  Victor Rodov, 
  • First Published: 28 June 2016
Review Article
Open Access

The Role of Omega-3 Polyunsaturated Fatty Acids in Stroke

Jiyuan Bu,  Yang Dou,  Xiaodi Tian,  Zhong Wang,  Gang Chen, 
  • First Published: 28 June 2016
Research Article
Open Access

Resveratrol Reduces the Incidence of Portal Vein System Thrombosis after Splenectomy in a Rat Fibrosis Model

Meng Xu,  Wanli Xue,  Zhenhua Ma,  Jigang Bai,  Shengli Wu, 
  • First Published: 28 June 2016
Research Article
Open Access

Serum Oxidized LDL Levels in Type 2 Diabetic Patients with Retinopathy in Mthatha Region of the Eastern Cape Province of South Africa

Farzana Ganjifrockwala,  Jim Joseph,  Grace George, 
  • First Published: 28 June 2016
Research Article
Open Access

The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBPβ rather than Enterotoxigenic Bacteroides fragilis Infection

Anastasiya V. Snezhkina,  George S. Krasnov,  Anastasiya V. Lipatova,  Asiya F. Sadritdinova,  Olga L. Kardymon,  Maria S. Fedorova,  Nataliya V. Melnikova,  Oleg A. Stepanov,  Andrew R. Zaretsky,  Andrey D. Kaprin,  Boris Y. Alekseev,  Alexey A. Dmitriev,  Anna V. Kudryavtseva, 
  • First Published: 28 June 2016
Letter to the Editor
Open Access

Comment on “The Impact of Chronic Tobacco Smoking on Retinal and Choroidal Thickness in Greek Population”

Salih Uzun, 
  • First Published: 28 June 2016

Research Article
Open Access

Parishin from Gastrodia elata Extends the Lifespan of Yeast via Regulation of Sir2/Uth1/TOR Signaling Pathway

Yanfei Lin,  Yujuan Sun,  Yufang Weng,  Akira Matsuura,  Lan Xiang,  Jianhua Qi, 
  • First Published: 27 June 2016
Research Article
Open Access

Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil’s Claw (Harpagophytum)

Mbaki Muzila,  Kimmo Rumpunen,  Helen Wright,  Helen Roberts,  Melissa Grant,  Hilde Nybom,  Jasna Sehic,  Anders Ekholm,  Cecilia Widén, 
  • First Published: 27 June 2016
Review Article
Open Access

New Pathogenic Concepts and Therapeutic Approaches to Oxidative Stress in Chronic Kidney Disease

José Pedraza-Chaverri,  Laura G. Sánchez-Lozada,  Horacio Osorio-Alonso,  Edilia Tapia,  Alexandra Scholze, 
  • First Published: 27 June 2016