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    2020
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Predictors for High-Risk Carotid Plaque in Asymptomatic Korean Population

Chae Won Jang,  Yong Kyun Kim,  Ki-Hong Kim,  Achangwa Chiara,  Moo-Sik Lee,  Jang-Ho Bae, 
  • First Published: 30 December 2020
Review Article
Open Access

Inherited Cardiac Arrhythmia Syndromes: Focus on Molecular Mechanisms Underlying TRPM4 Channelopathies

Mohamed-Yassine Amarouch,  Jaouad El Hilaly, 
  • First Published: 17 December 2020
Research Article
Open Access

Bazedoxifene Plays a Protective Role against Inflammatory Injury of Endothelial Cells by Targeting CD40

Wenmin Song,  Yu Lv,  Zizhao Tang,  Fangqin Nie,  Panhao Huang,  Qi Pei,  Ren Guo, 
  • First Published: 15 December 2020
Research Article
Open Access

Long Noncoding RNA HOTAIR Functions as a Competitive Endogenous RNA to Regulate Connexin43 Remodeling in Atrial Fibrillation by Sponging MicroRNA-613

Weiran Dai,  Xiaoying Chao,  Shanshan Li,  Shuang Zhou,  Guoqiang Zhong,  Zhiyuan Jiang, 
  • First Published: 18 November 2020
Research Article
Open Access

Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients

Yuanyuan Zhang,  Chunyang Tian,  Xuejian Liu,  He Zhang, 
  • First Published: 10 November 2020
Research Article
Open Access

Extended Renal Artery Denervation Is Associated with Artery Wall Lesions and Acute Systemic and Pulmonary Hemodynamic Changes: A Sham-Controlled Experimental Study

Aleksandr D. Vakhrushev,  Heber Ivan Condori Leandro,  Natalia S. Goncharova,  Lev E. Korobchenko,  Lubov B. Mitrofanova,  Dmitry S. Lebedev,  Evgeny N. Mikhaylov, 
  • First Published: 29 October 2020
Research Article
Open Access

Heart Rate Variability in Patients with Hypertension: the Effect of Metabolic Syndrome and Antihypertensive Treatment

Małgorzata Maciorowska,  Paweł Krzesiński,  Robert Wierzbowski,  Grzegorz Gielerak, 
  • First Published: 14 October 2020
Research Article
Open Access

The Effect of Early Treatment with Intravenous Magnesium Sulfate on the Incidence of Cardiac Comorbidities in Hospitalized Stroke Patients

Kameron Bechler,  Kristina Shkirkova,  Jeffrey L. Saver,  Sidney Starkman,  Scott Hamilton,  David S. Liebeskind,  Marc Eckstein,  Samuel Stratton,  Frank Pratt,  Robin Conwit,  Nerses Sanossian, 
  • First Published: 26 September 2020
Research Article
Open Access

Efficacy of Qishen Yiqi Drop Pill for Chronic Heart Failure: An Updated Meta-Analysis of 85 Studies

Hao Wang,  Lixia Li,  Xiaochun Qing,  Shouyan Zhang,  Shulong Li, 
  • First Published: 23 September 2020
Research Article
Open Access

Analysis of Clinical Efficacy of Traditional Chinese Medicine in Recovery Stage of Stroke: A Systematic Review and Meta-Analysis

Xue Zhang,  Xiao-Fei Zhang,  Lin Wang,  Dong-Yan Guo,  Jia-Min Zhang,  Yong-Gang Chen,  Zhi-Chao Wang,  Li-Shan Pei,  Jiang-Xue Chen,  Ya-Jun Shi,  Jun-Bo Zou, 
  • First Published: 22 September 2020
Research Article
Open Access

Low Ethanol Concentrations Promote Endothelial Progenitor Cell Capacity and Reparative Function

Lars Brodowski,  Bianca Schröder-Heurich,  Berina Kipke,  Cara Schmidt,  Constantin S. von Kaisenberg,  Frauke von Versen-Höynck, 
  • First Published: 22 September 2020
Review Article
Open Access

Patterns of Circadian Variation in 24-Hour Ambulatory Blood Pressure, Heart Rate, and Sympathetic Tone Correlate with Cardiovascular Disease Risk: A Cluster Analysis

Myung Han Hyun,  Jun Hyuk Kang,  Sunghwan Kim,  Jin Oh. Na,  Cheol Ung Choi,  Jin Won Kim,  Eung Ju Kim,  Seung-Woon Rha,  Chang Gyu Park,  Eunmi Lee,  Hong Seog Seo, 
  • First Published: 22 September 2020
Research Article
Open Access

Differential Effects of Combination of Renin-Angiotensin-Aldosterone System Inhibitors on Central Aortic Blood Pressure: A Cross-Sectional Observational Study in Hypertensive Outpatients

Akshyaya Pradhan,  Pravesh Vishwakarma,  Monika Bhandari,  Rishi Sethi,  Varun Shankar Narain, 
  • First Published: 08 September 2020
Research Article
Open Access

Drug-Coated Balloon for De Novo Coronary Artery Lesions: A Systematic Review and Trial Sequential Meta-analysis of Randomized Controlled Trials

Wei Liu,  Min Zhang,  Guangping Chen,  Zongzhuang Li,  Fang Wei, 
  • First Published: 01 September 2020
Research Article
Open Access

Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coronary Intervention

Altekin Refik Emre,  Kilinc Ali Yasar,  Yanikoglu Atakan,  Cicekcibasi Orhan,  Kucuk Murathan, 
  • First Published: 01 September 2020
Research Article
Open Access

Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19

Shi Tai,  Jianjun Tang,  Bilian Yu,  Liang Tang,  Yang Wang,  Huilin Zhang,  Weihong Zhu,  Kui Xiao,  Chuan Wen,  Chongqin Tan,  Zhongbiao Jiang,  Chuanhao Jiang,  Li Zhu,  Li Jiang,  Qiming Liu,  Xinqun Hu,  Zhenfei Fang,  Xuping Li,  Jiaxing Sun,  Zhaowei Zhu,  Hui Yang,  Tao Tu,  Yichao Xiao,  Mingxian Chen,  Yuhu He,  Xiangping Chai,  Junmei Xu,  Shenghua Zhou, 
  • First Published: 16 August 2020
Research Article
Open Access

Combined Aerobic and Resistance Exercises Evokes Longer Reductions on Ambulatory Blood Pressure in Resistant Hypertension: A Randomized Crossover Trial

Nayara Fraccari Pires,  Helio José Coelho-Júnior,  Bruno Bavaresco Gambassi,  Ana Paula Cabral de Faria,  Alessandra Mileni Versuti Ritter,  Catarina de Andrade Barboza,  Silvia Elaine Ferreira-Melo,  Bruno Rodrigues,  Heitor Moreno Júnior, 
  • First Published: 01 August 2020
Research Article
Open Access

Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses

Bin Zhao,  Dan Wang,  Yanling Liu,  Xiaohong Zhang,  Zheng Wan,  Jinling Wang,  Ting Su,  Linshan Duan,  Yan Wang,  Yuehua Zhang,  Yilin Zhao, 
  • First Published: 01 August 2020
Research Article
Open Access

Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease

Sylwia Wasiak,  Dean Gilham,  Emily Daze,  Laura M. Tsujikawa,  Christopher Halliday,  Stephanie C. Stotz,  Brooke D. Rakai,  Li Fu,  Ravi Jahagirdar,  Michael Sweeney,  Jan O. Johansson,  Norman C. W. Wong,  Ewelina Kulikowski, 
  • First Published: 01 August 2020
Research Article
Open Access

Characteristics of Hypoglycemic Diabetic Patients Visiting the Emergency Room

Tong Min Kim,  Hyunah Kim,  Seung-Hwan Lee,  Jae-Hyoung Cho,  Hyunyong Lee,  Hyeon Woo Yim,  Kun-Ho Yoon,  Hun-Sung Kim, 
  • First Published: 26 July 2020
Research Article
Open Access

Hemorheological Alterations in Patients with Heart Failure with Reduced Ejection Fraction Treated by Resveratrol

Roland Gal,  Dora Praksch,  Peter Kenyeres,  Miklos Rabai,  Kalman Toth,  Robert Halmosi,  Tamas Habon, 
  • First Published: 01 July 2020
Research Article
Open Access

MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy

Xiao-Yu Pan,  Zai-Wei Zhang, 
  • First Published: 01 July 2020
Research Article
Open Access

Evaluation of Cardiovascular Risk in Hidradenitis Suppurativa Patients Using Heart Rate Variability (HRV) Analysis

Nevena Skroza,  Alessandra Mambrin,  Ilaria Proietti,  Veronica Balduzzi,  Nicoletta Bernardini,  Anna Marchesiello,  Simone Michelini,  Ersilia Tolino,  Salvatore Volpe,  Patrizia Maddalena,  Antonella Ciaramella,  Gianfranco Raimondi,  Concetta Potenza, 
  • First Published: 01 July 2020
Review Article
Open Access

Antithrombotic Treatments in Patients with Chronic Coronary Artery Disease or Peripheral Artery Disease: A Systematic Review of Randomised Controlled Trials

Rupert Bauersachs,  Olivia Wu,  Jean-Baptiste Briere,  Kevin Bowrin,  Katarzyna Borkowska,  Anna Jakubowska,  Vanessa Taieb,  Mondher Toumi,  Maria Huelsebeck, 
  • First Published: 30 June 2020
Review Article
Open Access

Female Sex as a Thromboembolic Risk Factor in the Era of Nonvitamin K Antagonist Oral Anticoagulants

Mariacarla Gallù,  Giulia Marrone,  Jacopo Maria Legramante,  Antonino De Lorenzo,  Nicola Di Daniele,  Annalisa Noce, 
  • First Published: 27 June 2020
Clinical Study
Open Access

Cardiovascular Protection of Nephropathic Male Patients by Oral Food Supplements

Annalisa Noce,  Giulia Marrone,  Manuela Di Lauro,  Silvia Urciuoli,  Anna Pietroboni Zaitseva,  Georgia Wilson Jones,  Nicola Di Daniele,  Annalisa Romani, 
  • First Published: 25 June 2020
Research Article
Open Access

Recombinant Human Brain Natriuretic Peptide Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting CD4+ T Cell Proliferation via PI3K/AKT/mTOR Pathway Activation

Kun-Peng Li,  Hai-Yan Zhang,  Xiao-Dong Xu,  Ming-Yang,  Tie-Jun Li,  Shu-Tian Song, 
  • First Published: 23 June 2020
Research Article
Open Access

The Prevalence and Diagnostic Ratio of Familial Hypercholesterolemia (FH) and Proportion of Acute Coronary Syndrome in Japanese FH Patients in a Healthcare Record Database Study

Tamio Teramoto,  Tomohiro Sawa,  Satoshi Iimuro,  Hyoe Inomata,  Takashi Koshimizu,  Iori Sakakibara,  Katsutoshi Hiramatsu, 
  • First Published: 19 June 2020
Research Article
Open Access

Long Noncoding RNA TUG1 Promotes the Function in ox-LDL-Treated HA-VSMCs via miR-141-3p/ROR2 Axis

Yu Tang,  Jing Hu,  Zhiying Zhong,  Yanfeng Liu,  Yunxia Wang, 
  • First Published: 01 June 2020
Research Article
Open Access

Identification of Target Genes of Antiarrhythmic Traditional Chinese Medicine Wenxin Keli

Yusi Yao,  Yuhong Liu,  Zhihuan Zeng,  Yanqun Zhao,  Tudi Li,  Rong Chen,  Rendan Zhang, 
  • First Published: 01 June 2020
Research Article
Open Access

Drug Use Evaluation of Beta-Blockers in Medical Wards of Nedjo General Hospital, Western Ethiopia

Ginenus Fekadu,  Firomsa Bekele,  Kumera Bekele,  Sagni Hanbisa,  Gemechis Belay,  Mudasir Maqbool, 
  • First Published: 01 June 2020
Research Article
Open Access

Determinants of Selected Cardiovascular Diseases among Adult Patients at Cardiac Clinic of Debre Berhan Referral Hospital, Ethiopia: Unmatched Case-Control Study

Shenkut Aragaw,  Esubalew Tesfahun,  Behailu Tariku Derseh,  Betegiorgis Mamo, 
  • First Published: 27 May 2020
Review Article
Open Access

Platelet Responses in Cardiovascular Disease: Sex-Related Differences in Nutritional and Pharmacological Interventions

Valeria Gasperi,  M. Valeria Catani,  Isabella Savini, 
  • First Published: 27 May 2020
Research Article
Open Access

Long Noncoding RNA SOX2-OT Exacerbates Hypoxia-Induced Cardiomyocytes Injury by Regulating miR-27a-3p/TGFβR1 Axis

Guang Yang,  Chunsheng Lin, 
  • First Published: 23 May 2020
Research Article
Open Access

Cardioprotective Effect of (Z)-2-Acetoxy-3-(3,4-Dihydroxyphenyl) Acrylic Acid: Inhibition of Apoptosis in Cardiomyocytes

Wei Guo,  Zhijun Wang,  Hao Jue,  Chunnan Dong,  Cheng Yang, 
  • First Published: 01 May 2020
Research Article
Open Access

Association between Serum Vitamin C and the Blood Pressure: A Systematic Review and Meta-Analysis of Observational Studies

Li Ran,  Wenli Zhao,  Xiaodong Tan,  Hongwu Wang,  Kaito Mizuno,  Ken Takagi,  Ye Zhao,  Huaien Bu, 
  • First Published: 01 May 2020
Review Article
Open Access

α 2-Adrenoceptors: Challenges and Opportunities—Enlightenment from the Kidney

William A. Pettinger,  Edwin K. Jackson, 
  • First Published: 01 May 2020
Review Article
Open Access

Is Extra Virgin Olive Oil an Ally for Women’s and Men’s Cardiovascular Health?

Flavia Franconi,  Ilaria Campesi,  Annalisa Romani, 
  • First Published: 27 April 2020
Review Article
Open Access

Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyses of 50 Randomized Controlled Trials

Xiaodan Zhang,  Lu Xing,  Xiaona Jia,  Xiaocong Pang,  Qian Xiang,  Xia Zhao,  Lingyue Ma,  Zhiyan Liu,  Kun Hu,  Zhe Wang,  Yimin Cui, 
  • First Published: 27 April 2020
Research Article
Open Access

Left Ventricular Ejection Fraction Is Associated with the Risk of Thrombus in the Left Atrial Appendage in Patients with Atrial Fibrillation

Beata Uziębło-Życzkowska,  Paweł Krzesiński,  Agnieszka Jurek,  Agnieszka Kapłon-Cieślicka,  Iwona Gorczyca,  Monika Budnik,  Grzegorz Gielerak,  Marek Kiliszek,  Monika Gawałko,  Piotr Scisło,  Janusz Kochanowski,  Olga Jelonek,  Anna Michalska,  Katarzyna Starzyk,  Krzysztof J. Filipiak,  Beata Wożakowska-Kapłon,  Grzegorz Opolski, 
  • First Published: 27 April 2020
Research Article
Open Access

Association of β-Blocker Therapy at Discharge with Clinical Outcomes after Acute Coronary Syndrome in Patients without Heart Failure

Yan Chen,  Xiao-fang Tang,  Run-lin Gao,  Yue-jin Yang,  Bo Xu,  Jin-qing Yuan, 
  • First Published: 25 April 2020
Review Article
Open Access

Efficacy and Safety of Non-Vitamin K Anticoagulants for Atrial Fibrillation in Relation to Different Renal Function Levels: A Network Meta-Analysis

Hao Jin,  Kongbo Zhu,  Lina Wang,  Yifan Li,  Jingjun Meng,  Hong Zhi, 
  • First Published: 25 April 2020
Research Article
Open Access

Therapeutic Anticoagulation with Argatroban and Heparins Reduces Granulocyte Migration: Possible Impact on ECLS-Therapy?

Andre Bredthauer,  Manuel Kopfmueller,  Michael Gruber,  Sophie-Marie Pfaehler,  Karla Lehle,  Walter Petermichl,  Timo Seyfried,  Diane Bitzinger,  Andreas Redel, 
  • First Published: 25 April 2020
Review Article
Open Access

The Relation between Volume and Outcome of Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Jialing He,  Zhen Zhang,  Han Wang,  Lin Cai, 
  • First Published: 20 April 2020
Review Article
Open Access

Dual Antiplatelet Therapy Duration in Acute Coronary Syndrome Patients: The State of the Art and Open Issues

Monica Verdoia,  Cyril Camaro,  Elvin Kedhi,  Marco Marcolongo,  Harry Suryapranata,  Giuseppe De Luca, 
  • First Published: 07 April 2020
Research Article
Open Access

Isoliquiritigenin Inhibits Atherosclerosis by Blocking TRPC5 Channel Expression

Jie Qi,  Jianguo Cui,  Baobin Mi,  Xiaohong Yan,  Wenwen Xu,  Hui Ma,  Qingtan Zhang,  Fang Xu, 
  • First Published: 07 April 2020
Clinical Study
Open Access

Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial

Gordana Taleska Stupica,  Maja Sostaric,  Marija Bozhinovska,  Lea Rupert,  Zoran Bosnic,  Ales Jerin,  Alojz Ihan,  Tomislav Klokocovnik,  Matej Podbregar, 
  • First Published: 30 March 2020
Review Article
Open Access

The Role of Clopidogrel in 2020: A Reappraisal

Giuseppe Patti,  Giuseppe Micieli,  Claudio Cimminiello,  Leonardo Bolognese, 
  • First Published: 27 March 2020
Research Article
Open Access

Association between P2RY12 Gene Polymorphisms and IVIG Resistance in Kawasaki Patients

Zhouping Wang,  Yufen Xu,  Huazhong Zhou,  Yanfei Wang,  Wei Li,  Zhaoliang Lu,  Zhiyong Jiang,  Xueping Gu,  Hao Zheng,  Lanlan Zeng,  Ping Huang,  Li Zhang,  Xiaoqiong Gu, 
  • First Published: 10 March 2020
Review Article
Open Access

Effects of Angiotensin-Converting Enzyme Inhibitors on Arterial Stiffness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Xiuli Li,  Peng Chang,  Qiongying Wang,  Hao Hu,  Feng Bai,  Ningyin Li,  Jing Yu, 
  • First Published: 01 March 2020
Research Article
Open Access

Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention

Ming Gao,  Xinying Zhang,  Ling Qin,  Yang Zheng,  Zhiguo Zhang,  Qian Tong,  Hang Li, 
  • First Published: 01 March 2020
Research Article
Open Access

Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome

Shi Tai,  Xuping Li,  Zhaowei Zhu,  Liang Tang,  Hui Yang,  Liyao Fu,  Xinqun Hu,  Zhenfei Fang,  Shenghua Zhou, 
  • First Published: 22 February 2020
Research Article
Open Access

Bredemolic Acid Improves Cardiovascular Function and Attenuates Endothelial Dysfunction in Diet-Induced Prediabetes: Effects on Selected Markers

Akinjide Moses Akinnuga,  Angezwa Siboto,  Bongiwe Khumalo,  Ntethelelo Hopewell Sibiya,  Phikelelani Ngubane,  Andile Khathi, 
  • First Published: 11 February 2020
Research Article
Open Access

A Nomogram Based on Apelin-12 for the Prediction of Major Adverse Cardiovascular Events after Percutaneous Coronary Intervention among Patients with ST-Segment Elevation Myocardial Infarction

Enfa Zhao,  Hang Xie,  Yushun Zhang, 
  • First Published: 06 February 2020
Research Article
Open Access

The Functional Severity Assessment of Coronary Stenosis Using Coronary Computed Tomography Angiography-Based Myocardial Mass at Risk and Minimal Lumen Diameter

Kenji Sadamatsu,  Kazuhiro Nagaoka,  Yasuaki Koga,  Kotaro Kagiyama,  Kohei Muramatsu,  Kiyoshi Hironaga,  Hideki Tashiro,  Takafumi Ueno,  Yoshihiro Fukumoto, 
  • First Published: 31 January 2020
Research Article
Open Access

Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway

Hong-Bing Wu,  Zhi-Wei Wang,  Feng Shi,  Zong-Li Ren,  Luo-Cheng Li,  Xiao-Ping Hu,  Rui Hu,  Bo-Wen Li, 
  • First Published: 21 January 2020
Research Article
Open Access

Angiographic Restenosis in Coronary Bifurcations Treatment with Regular Drug Eluting Stents and Dedicated Bifurcation Drug-Eluting BiOSS Stents: Analysis Based on Randomized POLBOS I and POLBOS II Studies

Robert J. Gil,  Jacek Bil,  Adam Kern,  Luis A. Iñigo-Garcia,  Radoslaw Formuszewicz,  Slawomir Dobrzycki,  Dobrin Vassilev,  Roxana Mehran, 
  • First Published: 21 January 2020
Review Article
Open Access

Drug-Coated Balloons versus Everolimus-Eluting Stents in Patients with In-Stent Restenosis: A Pair-Wise Meta-Analysis of Randomized Trials

Nina Peng,  Wei Liu,  Zongzhuang Li,  Jun Wei,  Xuejun Chen,  Wei Wang,  Hao Lin, 
  • First Published: 21 January 2020
Review Article
Open Access

Exploring Current Evidence on the Past, the Present, and the Future of the Heart Team: A Narrative Review

Alexandru Burlacu,  Adrian Covic,  Mircea Cinteza,  Paula Madalina Lupu,  Radu Deac,  Grigore Tinica, 
  • First Published: 04 January 2020
Research Article
Open Access

Lipid Lowering Treatment and Eligibility for PCSK9 Inhibition in Post-Myocardial Infarction Patients in Italy: Insights from Two Contemporary Nationwide Registries

Furio Colivicchi,  Michele Massimo Gulizia,  Marcello Arca,  Pier Luigi Temporelli,  Lucio Gonzini,  Vanessa Venturelli,  Nuccia Morici,  Ciro Indolfi,  Domenico Gabrielli,  Leonardo De Luca, 
  • First Published: 03 January 2020
Clinical Study
Open Access

Predictive Value of Electromechanical Activation Time for In-Hospital Major Cardiac Adverse Events in Heart Failure Patients

Jing Zhang,  Wen-Xian Liu,  Shu-Zheng Lyu, 
  • First Published: 03 January 2020