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    2018
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Research Article
Open Access

Homocysteine and Digestive Tract Cancer Risk: A Dose-Response Meta-Analysis

Jun Xu,  Xin Zhao,  Shanwen Sun,  Peng Ni,  Chujun Li,  Anjing Ren,  Wei Wang,  Lingjun Zhu, 
  • First Published: 18 December 2018
Research Article
Open Access

The De Ritis and Neutrophil-to-Lymphocyte Ratios May Aid in the Risk Assessment of Patients with Metastatic Renal Cell Carcinoma

Sung Han Kim,  Eun Young Park,  Jungnam Joo,  Jinsoo Chung, 
  • First Published: 18 December 2018
Research Article
Open Access

Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome–Wide Association Study

Chengkun Yang,  Chuangye Han,  Xiangkun Wang,  Xiwen Liao,  Xiaoguang Liu,  Wei Qin,  Long Yu,  Guangzhi Zhu,  Hao Su,  Sicong Lu,  Zhiwei Chen,  Tingdong Yu,  Zhen Liu,  Ketuan Huang,  Zhengtao Liu,  Yu Liang,  Jianlu Huang,  Tao Peng, 
  • First Published: 18 December 2018
Research Article
Open Access

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer

Matthew P. Humphries,  Sean Hynes,  Victoria Bingham,  Delphine Cougot,  Jacqueline James,  Farah Patel-Socha,  Eileen E. Parkes,  Jaine K. Blayney,  Michael A. O’Rorke,  Gareth W. Irwin,  Darragh G. McArt,  Richard D. Kennedy,  Paul B. Mullan,  Stephen McQuaid,  Manuel Salto-Tellez,  Niamh E. Buckley, 
  • First Published: 17 December 2018
Research Article
Open Access

Secretory High-Mobility Group Box 1 Protein Affects Regulatory T Cell Differentiation in Neuroblastoma Microenvironment In Vitro

Thitinee Vanichapol,  Wararat Chiangjong,  Jirawan Panachan,  Usanarat Anurathapan,  Somchai Chutipongtanate,  Suradej Hongeng, 
  • First Published: 16 December 2018
Review Article
Open Access

Glucose and Lactate Transport in Pancreatic Cancer: Glycolytic Metabolism Revisited

Miles E. Cameron,  Anastasiya Yakovenko,  Jose G. Trevino, 
  • First Published: 04 December 2018
Research Article
Open Access

Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment

Mengyuan Li,  Zhixian Liu,  Xiaosheng Wang, 
  • First Published: 02 December 2018
Research Article
Open Access

Efficacy of Immunotherapy in Patients with Metastatic Mucosal or Uveal Melanoma

Claire Mignard,  Aurélie Deschamps Huvier,  André Gillibert,  Anne Bénédicte Duval Modeste,  Caroline Dutriaux,  Amir Khammari,  Marie-Françoise Avril,  Nora Kramkimel,  Laurent Mortier,  Pierre Marcant,  Thierry Lesimple,  Caroline Gaudy-Marqueste,  Candice Lesage,  Laurent Machet,  François Aubin,  Nicolas Meyer,  Nathalie Beneton,  Géraldine Jeudy,  Henri Montaudié,  Jean-Philippe Arnault,  Laetitia Visseaux,  Sabiha Trabelsi,  Mona Amini-Adle,  Eve Maubec,  Yannick Le Corre,  Dan Lipsker,  Ewa Wierzbicka-Hainaut,  Noémie Litrowski,  Andreea Stefan,  Florence Brunet-Possenti,  Marie-Thérèse Leccia,  Pascal Joly, 
  • First Published: 02 December 2018
Research Article
Open Access

Quantitative Metastatic Lymph Node Regions on Magnetic Resonance Imaging Are Superior to AJCC N Classification for the Prognosis of Nasopharyngeal Carcinoma

Xin Zhou,  Xiaomin Ou,  Youqi Yang,  Tingting Xu,  Chunying Shen,  Jianhui Ding,  Chaosu Hu, 
  • First Published: 02 December 2018
Review Article
Open Access

Transforming of the Tumor Microenvironment: Implications for TGF-β Inhibition in the Context of Immune-Checkpoint Therapy

Stefanie Löffek, 
  • First Published: 02 December 2018
Review Article
Open Access

Resection of Liver Metastases: A Treatment Provides a Long-Term Survival Benefit for Patients with Advanced Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis

Xinzhe Yu,  Jichun Gu,  Haoxuan Wu,  Deliang Fu,  Ji Li,  Chen Jin, 
  • First Published: 14 November 2018
Research Article
Open Access

Differential Expression of Prostaglandin I2 Synthase Associated with Arachidonic Acid Pathway in the Oral Squamous Cell Carcinoma

Anelise Russo,  Patrícia M. Biselli-Chicote,  Rosa S. Kawasaki-Oyama,  Márcia M. U. Castanhole-Nunes,  José V. Maniglia,  Dalísio de Santi Neto,  Érika C. Pavarino,  Eny M. Goloni-Bertollo, 
  • First Published: 08 November 2018
Research Article
Open Access

PPARα Enhances Cancer Cell Chemotherapy Sensitivity by Autophagy Induction

Mengli You,  Jiaming Gao,  Jianhua Jin,  Yongzhong Hou, 
  • First Published: 04 November 2018
Research Article
Open Access

Risk Factors for Fatal Pulmonary Hemorrhage following Concurrent Chemoradiotherapy in Stage 3B/C Squamous-Cell Lung Carcinoma Patients

Erkan Topkan,  Ugur Selek,  Yurday Ozdemir,  Ali A. Besen,  Ozan C. Guler,  Berna A. Yildirim,  Huseyin Mertsoylu,  Alper Findikcioglu,  Ozgur Ozyilkan,  Berrin Pehlivan, 
  • First Published: 01 November 2018
Research Article
Open Access

Small or Non-Small Cell Lung Cancer Based Therapy for Treatment of Large Cell Neuroendocrine Cancer of The Lung? University of Cincinnati Experience

Ihab Eldessouki,  Ola Gaber,  Tariq Namad,  Jiang Wang,  John C. Morris,  Nagla Abdel Karim, 
  • First Published: 01 November 2018
Review Article
Open Access

Immunomodulatory Effects of Drugs for Effective Cancer Immunotherapy

Maiko Matsushita,  Mai Kawaguchi, 
  • First Published: 25 October 2018
Research Article
Open Access

Overexpression of IRS-4 Correlates with Procaspase 3 Levels in Tumoural Tissue of Patients with Colorectal Cancer

Patricia Sanmartín-Salinas,  Luis G. Guijarro, 
  • First Published: 16 October 2018
Research Article
Open Access

Prognostic Factors Predicting Poor Outcome in Cancer Patients with Febrile Neutropenia in the Emergency Department: Usefulness of qSOFA

Seung Jae Lee,  Ji Hye Kim,  Seung Baik Han,  Jin Hui Paik,  Areum Durey, 
  • First Published: 11 October 2018
Review Article
Open Access

Treatment-Related Adverse Effects in Lung Cancer Patients after Stereotactic Ablative Radiation Therapy

Stamati Morias,  Loredana G. Marcu,  Michala Short,  Eileen Giles,  Andrew Potter,  Justin Shepherd,  Thanh Gierlach,  Eva Bezak, 
  • First Published: 04 October 2018
Review Article
Open Access

Current Role of Chemotherapy in Nonmetastatic Nasopharyngeal Cancer

Tapesh Bhattacharyya,  Geethu Babu,  Cessal Thommachan Kainickal, 
  • First Published: 01 October 2018
Research Article
Open Access

Basal Cell Carcinoma Arises from Interfollicular Layer of Epidermis

Sukmawati Tansil Tan,  Mahmud Ghaznawie,  Peter J. Heenan,  Ricky Dosan, 
  • First Published: 26 September 2018
Research Article
Open Access

HBV-DNA Load-Related Peritumoral Inflammation and ALBI Scores Predict HBV Associated Hepatocellular Carcinoma Prognosis after Curative Resection

Rui Liao,  Cheng-You Du,  Jian-Ping Gong,  Fang Luo, 
  • First Published: 20 September 2018
Research Article
Open Access

Additional Biomarkers beyond RAS That Impact the Efficacy of Cetuximab plus Chemotherapy in mCRC: A Retrospective Biomarker Analysis

Peng Zheng,  Chunmin Liang,  Li Ren,  Dexiang Zhu,  Qingyang Feng,  Wenju Chang,  Guodong He,  Lechi Ye,  Jingwen Chen,  Qi Lin,  Tuo Yi,  Meiling Ji,  Zhengchuan Niu,  Mi Jian,  Ye Wei,  Jianmin Xu, 
  • First Published: 16 September 2018
Clinical Study
Open Access

Outcomes Following Salvage Radiation and Systemic Therapy for Isolated Locoregional Recurrence of Breast Cancer after Mastectomy: Impact of Constructed Biologic Subtype

Xiaofang Wang,  Jinli Ma,  Xin Mei,  Zhaozhi Yang,  Xiaoli Yu,  Xiaomao Guo,  Zhen Zhang,  Zhimin Shao, 
  • First Published: 12 September 2018
Research Article
Open Access

The Utility of Preoperative Vascular Grading in Patients Undergoing Surgery First for Pancreatic Cancer: Does Radiologic Arterial or Venous Involvement Predict Pathologic Margin Status?

Neha Goel,  Jimson W. D’Souza,  Karen J. Ruth,  Barton Milestone,  Andreas Karachristos,  Rajeswari Nagarathinam,  Harry Cooper,  John Hoffman,  Sanjay Reddy, 
  • First Published: 13 August 2018
Research Article
Open Access

A Machine Learning Approach for the Association of ki-67 Scoring with Prognostic Factors

E. Dirican,  E. Kiliç, 
  • First Published: 07 August 2018
Research Article
Open Access

Correlation between Psychosocial Distress and Quality of Life in Patients with Nasopharyngeal Carcinoma following Radiotherapy

Xiaolan Wang,  Yue Lv,  Wen Li,  Chen Gan,  Haijun Chen,  Yingying Liu,  Herta H. Chao,  Chiang-Shan R. Li,  Huaidong Cheng, 
  • First Published: 06 August 2018
Review Article
Open Access

MiR-30a: A Novel Biomarker and Potential Therapeutic Target for Cancer

Lin-hong Jiang,  He-da Zhang,  Jin-hai Tang, 
  • First Published: 06 August 2018
Research Article
Open Access

The Association of Simultaneous Increase in Interleukin-6, C Reactive Protein, and Matrix Metalloproteinase-9 Serum Levels with Increasing Stages of Colorectal Cancer

Ismar Rasic,  Velma Rebic,  Azra Rasic,  Goran Aksamija,  Svjetlana Radovic, 
  • First Published: 30 July 2018
Research Article
Open Access

Inhibition of MDM2 via Nutlin-3A: A Potential Therapeutic Approach for Pleural Mesotheliomas with MDM2-Induced Inactivation of Wild-Type P53

Robert F. H. Walter,  Robert Werner,  Michael Wessolly,  Elena Mairinger,  Sabrina Borchert,  Jan Schmeller,  Jens Kollmeier,  Thomas Mairinger,  Thomas Hager,  Agnes Bankfalvi,  Daniel C. Christoph,  Wilfried E. E. Eberhardt,  Till Plönes,  Clemens Aigner,  Kurt W. Schmid,  Jeremias Wohlschlaeger,  Fabian D. Mairinger, 
  • First Published: 17 July 2018
Review Article
Open Access

Clinical and Molecular Characteristics Associated with Survival in Advanced Melanoma Treated with Checkpoint Inhibitors

Sunil Badami,  Sunil Upadhaya,  Ravi Kanth Velagapudi,  Pushyami Mikkilineni,  Ranju Kunwor,  Samer Al Hadidi,  Ghassan Bachuwa, 
  • First Published: 17 July 2018
Research Article
Open Access

S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer

Sabahattin Destek,  Vahit Onur Gul, 
  • First Published: 09 July 2018
Review Article
Open Access

The Role of the Vagus Nerve in Cancer Prognosis: A Systematic and a Comprehensive Review

Marijke De Couck,  Ralf Caers,  David Spiegel,  Yori Gidron, 
  • First Published: 02 July 2018
Review Article
Open Access

Research Priorities and Resource Allocation in the Investigation of New Drugs for Cancer in Least Developed Countries

Ricardo Eccard da Silva,  Angélica Amorim Amato,  Débora Dornelas Belchior Costa Andrade,  Alessandra Vanessa Leite e Silva,  Marta Rodrigues de Carvalho,  Maria Rita Carvalho Garbi Novaes, 
  • First Published: 02 July 2018
Research Article
Open Access

Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine

Vignesh K. Alamanda,  Myra M. Robinson,  Jeffrey S. Kneisl,  Leo R. Spector,  Joshua C. Patt, 
  • First Published: 25 June 2018
Research Article
Open Access

Advancing Parental Age and Risk of Solid Tumors in Children: A Case-Control Study in Peru

Ligia Rios,  Liliana Vásquez,  Mónica Oscanoa,  Iván Maza,  Jenny Gerónimo, 
  • First Published: 19 June 2018
Research Article
Open Access

TFF1 and TFF3 mRNAs Are Higher in Blood from Breast Cancer Patients with Metastatic Disease than Those without

Marwa H. Elnagdy,  Omar Farouk,  Amal K. Seleem,  Hoda A. Nada, 
  • First Published: 07 June 2018
Review Article
Open Access

Epimutation and Cancer: Carcinogenesis Viewed as Error-Prone Inheritance of Epigenetic Information

Patrick A. Riley, 
  • First Published: 03 June 2018
Research Article
Open Access

Complex Karyotype in Hematological Diseases: A 6-Year Single Centre Study from Pakistan

Samra Waheed,  Jawad Hassan,  Maliha Naz,  Sidra Maqsood,  Madiha Abid,  Saira Shan,  Muhammad Nadeem,  Tahir S. Shamsi, 
  • First Published: 03 June 2018
Research Article
Open Access

Multifactorial Analysis of Mortality in Screening Detected Lung Cancer

Subba R. Digumarthy,  Ruben De Man,  Rodrigo Canellas,  Alexi Otrakji,  Ge Wang,  Mannudeep K. Kalra, 
  • First Published: 16 May 2018
Research Article
Open Access

Capecitabine and Temozolomide in Neuroendocrine Tumor of Unknown Primary

Aman Chauhan,  Zainab Farooqui,  Le Aundra Murray,  Heidi L. Weiss,  Zin War Myint,  Arun Kumar A. Raajasekar,  B. Mark Evers,  Susanne Arnold,  Lowell Anthony, 
  • First Published: 07 May 2018
Research Article
Open Access

The Plasticity of CD4+CD25+FOXP3+CD127low T Cells in Patients with Metastatic Renal Cell Carcinoma in the Course of Interferon-Alpha Immunotherapy

Maria S. Sayapina,  Svetlana N. Bykovskaia, 
  • First Published: 02 May 2018
Review Article
Open Access

Multiple Myeloma of the Central Nervous System: 13 Cases and Review of the Literature

Gergely Varga,  Gábor Mikala,  László Gopcsa,  Zoltán Csukly,  Sarolta Kollai,  György Balázs,  Tímár Botond,  Nikolett Wohner,  Laura Horváth,  Gergely Szombath,  Péter Farkas,  Tamás Masszi, 
  • First Published: 23 April 2018
Review Article
Open Access

Hereditary Nonpolyposis Colorectal Cancer and Cancer Syndromes: Recent Basic and Clinical Discoveries

Erbao Chen,  Xiaojing Xu,  Tianshu Liu, 
  • First Published: 23 April 2018
Research Article
Open Access

Health Related Quality of Life of Cancer Patients in Ethiopia

Tadesse Melaku Abegaz,  Asnakew Achaw Ayele,  Begashaw Melaku Gebresillassie, 
  • First Published: 15 April 2018
Research Article
Open Access

The Caribbean Community Clinical Oncology Workforce: Analyzing Where We Are Today and Projecting for Tomorrow

Kellie Alleyne-Mike, 
  • First Published: 15 April 2018
Clinical Study
Open Access

Evaluation of Reirradiation in Locally Advanced Head and Neck Cancers: Toxicity and Early Clinical Outcomes

Amit Bahl,  Arun Singh Oinam,  Arun Elangovan,  Satinder Kaur,  Gaurav Trivedi,  Roshan Verma,  Sudhir Bhandari,  Sushmita Ghoshal,  Naresh Kumar Panda, 
  • First Published: 26 March 2018
Review Article
Open Access

Quality of Life, Depression, and Anxiety in Patients with Uveal Melanoma: A Review

Mario Miniati,  Maria Grazia Fabrini,  Federica Genovesi Ebert,  Maricia Mancino,  Alessandra Maglio,  Gabriele Massimetti,  Enrico Massimetti,  Donatella Marazziti, 
  • First Published: 20 March 2018
Research Article
Open Access

Experience and Expectations of Ovarian Cancer Patients in Australia

Catherine M. Holliday,  Maria Morte,  Josephine M. Byrne,  Anne T. Holliday, 
  • First Published: 07 March 2018
Research Article
Open Access

Intraoral Potentially Malignant Disorders in a Brazilian Oral Pathology Service: Epidemiological, Clinical, and Histopathological Findings

Fernanda Weber Mello,  Gilberto Melo,  Maria Inês Meurer,  Elena Riet Correa Rivero, 
  • First Published: 01 March 2018
Research Article
Open Access

RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer

Zonggao Shi,  Chunyan Li,  Laura Tarwater,  Jun Li,  Yang Li,  William Kaliney,  Darshan S. Chandrashekar,  M. Sharon Stack, 
  • First Published: 14 February 2018
Research Article
Open Access

The Efficacy of Conventionally Fractionated Radiation in the Management of Osseous Metastases from Metastatic Renal Cell Carcinoma

Rohit Gunan Ganju,  Mindi TenNapel,  Nicholas Mahan,  Amir Zahra,  Xinglei Shen, 
  • First Published: 09 January 2018